Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor α-positive breast cancer

Oncogene

Volumn 34, Issue 29, 2015, Pages 3760-3769

  Andruska, N ^a,b   Zheng, X ^a   Yang, X ^c   Helferich, W G ^b,c,d   Shapiro, D J ^a,b,d  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ACTIVATING TRANSCRIPTION FACTOR 6ALPHA; CALCIUM; CALCIUM CHANNEL; CHAPERONE; CHOLESTEROL; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; INOSITOL 1,4,5 TRISPHOSPHATE; MITOGENIC AGENT; PHOSPHOLIPASE C GAMMA; SMALL INTERFERING RNA; TAMOXIFEN; UNCLASSIFIED DRUG; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; ESTROGEN; ESTROGEN RECEPTOR ALPHA, HUMAN; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST CANCER; CALCIUM TRANSPORT; CANCER CELL; CANCER RESISTANCE; CANCER SURVIVAL; CANCER THERAPY; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL ASSESSMENT; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME INHIBITION; GENE ACTIVATION; GENE EXPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SYNTHESIS; TUMOR RECURRENCE; TUMOR XENOGRAFT; UNFOLDED PROTEIN RESPONSE; ANIMAL; BREAST NEOPLASMS; CONFOCAL MICROSCOPY; DNA MICROARRAY; DRUG EFFECTS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; KAPLAN MEIER METHOD; MCF-7 CELL LINE; METABOLISM; NUDE MOUSE; OVARIECTOMY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE; WESTERN BLOTTING; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAT-SHOCK PROTEINS; HUMANS; KAPLAN-MEIER ESTIMATE; MCF-7 CELLS; MICE, NUDE; MICROSCOPY, CONFOCAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OVARIECTOMY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TAMOXIFEN; TRANSPLANTATION, HETEROLOGOUS; UNFOLDED PROTEIN RESPONSE;

EID: 84937510292     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.292     Document Type: Article

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