An RNA-binding protein, Lin28, recognizes and remodels G-quartets in the MicroRNAs (miRNAs) and mRNAs it regulates

Journal of Biological Chemistry

Volumn 290, Issue 29, 2015, Pages 17909-17922

  O'Day, Elizabeth ^a,b   Le, Minh T N ^b   Imai, Shunsuke ^a   Tan, Shen Mynn ^b   Kirchner, Rory ^c   Arthanari, Haribabu ^a   Hofmann, Oliver ^c   Wagner, Gerhard ^a   Lieberman, Judy ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; HYDROGEN BONDS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS; STEM CELLS;

COLONY FORMATION; FLUORESCENT DYES; HUMAN EMBRYONAL CARCINOMA CELLS; PLANAR STRUCTURE; RNA SEQUENCES; RNA-BINDING PROTEIN; STRUCTURAL FEATURE; TERMINAL LOOPS;

RNA;

BINDING PROTEIN; CYCLIN B1; CYCLIN DEPENDENT KINASE 4; LIN28 PROTEIN; MESSENGER RNA; MICRORNA; MICRORNA 21; MICRORNA 34A; MICRORNA LET 7; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN HMGA1; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; GUANINE QUADRUPLEX; LIN-28 PROTEIN, HUMAN; LIN-28 PROTEIN, MOUSE; MESOPORPHYRIN; N-METHYLMESOPORPHYRIN IX; PROTEIN BINDING;

ARTICLE; COLONY FORMATION; CONTROLLED STUDY; EMBRYO; GEL MOBILITY SHIFT ASSAY; GENE SEQUENCE; HUMAN; HUMAN CELL; HYDROGEN BOND; LIN28 GENE; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN TARGETING; REGULATOR GENE; REGULATORY MECHANISM; RNA SEQUENCE; ANIMAL; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTATION; NUCLEOTIDE SEQUENCE;

ANIMALS; BASE SEQUENCE; CELL LINE; G-QUADRUPLEXES; HUMANS; MESOPORPHYRINS; MICE; MICRORNAS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; RNA, MESSENGER; RNA-BINDING PROTEINS;

EID: 84937509617     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.665521     Document Type: Article

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