Antiangiogenic Activity of Mononuclear Copper(II) Polypyridyl Complexes for the Treatment of Cancers

Journal of Medicinal Chemistry

Volumn 58, Issue 13, 2015, Pages 5226-5241

  Nagababu, Penumaka ^a   Barui, Ayan Kumar ^a,d   Thulasiram, Bathini ^a   Devi, C Shobha ^b   Satyanarayana, S ^c   Patra, Chitta Ranjan ^a,d   Sreedhar, Bojja ^a,d  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b NATIONAL DONG HWA UNIVERSITY   (Taiwan)

^c OSMANIA UNIVERSITY   (India)

^d ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC METAL COMPLEX; CN PIP; COPPER COMPLEX; COPPER(II) POLYPYRIDYL COMPLEX; CYTOTOXIC AGENT; DOXORUBICIN; IMIDAZOLE DERIVATIVE; PHENANTHROLINE DERIVATIVE; PIP; PROTEIN BAX; PYIP; PYRIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; TF PIP; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CALF THYMUS DNA; COORDINATION COMPOUND; COPPER; DNA; PROTEIN BINDING; PYRIDINE;

ABSORPTION SPECTROSCOPY; ANGIOGENESIS ASSAY; ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL LINE; CHICK EMBRYO; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SYNTHESIS; DRUG UPTAKE; EMBRYO; FEMALE; FLAME PHOTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PROTEIN DNA BINDING; STRUCTURE ACTIVITY RELATION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; VISCOMETRY; ANGIOGENESIS; ANIMAL; APOPTOSIS; CELL CULTURE; CELL CYCLE; CELL MOTION; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DNA CLEAVAGE; DRUG EFFECTS; FLOW CYTOMETRY; METABOLISM; NEOPLASMS; PATHOLOGY; SYNTHESIS; WESTERN BLOTTING;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHICK EMBRYO; COORDINATION COMPLEXES; COPPER; DNA; DNA CLEAVAGE; FLOW CYTOMETRY; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NEOPLASMS; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN BINDING; PYRIDINES; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84937501242     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.5b00651     Document Type: Article

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