Cellular uptake, cytotoxicity, apoptosis and DNA-binding investigations of Ru(II) complexes

European Journal of Medicinal Chemistry

Volumn 72, Issue , 2014, Pages 160-169

  Shobha Devi, C ^a   Nagababu, Penumaka ^a   Natarajan, Sumathi ^a   Deepika, N ^a   Venkat Reddy, P ^a   Veerababu, N ^a   Singh, Surya S ^a   Satyanarayana, S ^a  

^a OSMANIA UNIVERSITY   (India)

Author keywords

Apoptosis; Cellular uptake; Cytotoxicity; DNA binding; Fluorescence

Indexed keywords

CISPLATIN; PLASMID DNA; RUTHENIUM COMPLEX; ANTINEOPLASTIC AGENT; DNA; ORGANOMETALLIC COMPOUND; RUBIDIUM;

ABSORPTION SPECTROSCOPY; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BASE PAIRING; CARBON NUCLEAR MAGNETIC RESONANCE; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; COMET ASSAY; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; COVALENT BOND; DNA BINDING; DNA CLEAVAGE; DRUG BINDING; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; FEMALE; FLAME PHOTOMETRY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDROGEN BOND; IN VITRO STUDY; INFRARED SPECTROSCOPY; LIPOPHILICITY; LYMPHOCYTE; MOLECULAR DOCKING; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; ULTRAVIOLET SPECTROPHOTOMETRY; VISCOMETRY; VISCOSITY; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; HELA CELL LINE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BINDING SITES; CELL LINE, TUMOR; CELL SURVIVAL; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; ORGANOMETALLIC COMPOUNDS; RUBIDIUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84892737106     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.11.005     Document Type: Article

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