Intestinal CD169 + macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

Nature Communications

Volumn 6, Issue , 2015, Pages

  Asano, Kenichi ^a,b   Takahashi, Naomichi ^a   Ushiki, Mikiko ^a   Monya, Misa ^a   Aihara, Fumiaki ^a   Kuboki, Erika ^a   Moriyama, Shigetaka ^a   Iida, Mayumi ^a   Kitamura, Hiroshi ^c   Qiu, Chun Hong ^d   Watanabe, Takashi ^e   Tanaka, Masato ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c RAKUNO GAKUEN UNIVERSITY   (Japan)

^d SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^e Institute of Physical and Chemical Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD64 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; COLONY STIMULATING FACTOR 1; CXCL2 CHEMOKINE; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 2; SIALOADHESIN; TUMOR NECROSIS FACTOR ALPHA; CCL8 PROTEIN, MOUSE; DEXTRAN SULFATE; SIGLEC1 PROTEIN, MOUSE;

ANTIGEN; BLOOD; CELLS AND CELL COMPONENTS; DISEASE CONTROL; DISEASE INCIDENCE; INJURY; MICROBIOLOGY; RODENT; SECRETION; SYMPTOM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE RELEASE; EOSINOPHIL; EXPERIMENTAL COLITIS; FEMALE; GENE EXPRESSION; GENETIC RECOMBINATION; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; INTESTINAL MACROPHAGE; LAMINA PROPRIA; LYMPHOID CELL; MACROPHAGE; MICROENVIRONMENT; MONOCYTE; MOUSE; MUCOSA INFLAMMATION; MUCOSAL IMMUNITY; NONHUMAN; PHENOTYPE; PROTEIN DEPLETION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; UPREGULATION; ANIMAL; CHEMICALLY INDUCED; COLITIS; COLON; IMMUNOLOGY; METABOLISM; MUCOSA; PHYSIOLOGY; SECRETION (PROCESS);

MUS;

ANIMALS; CHEMOKINE CCL8; COLITIS; COLON; DEXTRAN SULFATE; FEMALE; IMMUNITY, MUCOSAL; MACROPHAGES; MICE; MONOCYTES; MUCOUS MEMBRANE; SIALIC ACID BINDING IG-LIKE LECTIN 1;

EID: 84937484873     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8802     Document Type: Article

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