메뉴 건너뛰기




Volumn 9, Issue , 2015, Pages 3653-3663

Bacteriophage-based therapy in cystic fibrosis-associated Pseudomonas aeruginosa infections: Rationale and current status

Author keywords

Bacterial infection; Multidrug resistance; Pneumonia; Pulmonary infection

Indexed keywords

ANTIBIOTIC AGENT; LIPOSOME; STREPTOMYCIN; SULFADIAZINE SILVER; TOBRAMYCIN;

EID: 84937469033     PISSN: None     EISSN: 11778881     Source Type: Journal    
DOI: 10.2147/DDDT.S53123     Document Type: Review
Times cited : (65)

References (68)
  • 1
    • 84930897566 scopus 로고    scopus 로고
    • Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients
    • Epub December 2
    • Ciofu O, Tolker-Nielsen T, Jensen PO, Wang H, Høiby N. Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients. Adv Drug Deliv Rev. 2014. Epub December 2.
    • (2014) Adv Drug Deliv Rev
    • Ciofu, O.1    Tolker-Nielsen, T.2    Jensen, P.O.3    Wang, H.4    Høiby, N.5
  • 2
    • 0036320272 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa and other predictors of mortality and morbidity in young children with cystic fibrosis
    • Emerson J, Rosenfeld M, McNamara S, Ramsey B, Gibson RL. Pseudomonas aeruginosa and other predictors of mortality and morbidity in young children with cystic fibrosis. Pediatr Pulmonol. 2002; 34(2):91–100.
    • (2002) Pediatr Pulmonol , vol.34 , Issue.2 , pp. 91-100
    • Emerson, J.1    Rosenfeld, M.2    McNamara, S.3    Ramsey, B.4    Gibson, R.L.5
  • 3
    • 12844270608 scopus 로고    scopus 로고
    • Longitudinal development of mucoid Pseudomonas aeruginosa infection and lung disease progression in children with cystic fibrosis
    • Li Z, Kosorok MR, Farrell PM, et al. Longitudinal development of mucoid Pseudomonas aeruginosa infection and lung disease progression in children with cystic fibrosis. JAMA. 2005;293(5):581–588.
    • (2005) JAMA , vol.293 , Issue.5 , pp. 581-588
    • Li, Z.1    Kosorok, M.R.2    Farrell, P.M.3
  • 4
    • 33645504787 scopus 로고    scopus 로고
    • Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis
    • Langton Hewer SC, Smyth AR. Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis. Cochrane Database Syst Rev. 2009;(4)CD004197.
    • (2009) Cochrane Database Syst Rev , Issue.4
    • Langton Hewer, S.C.1    Smyth, A.R.2
  • 5
    • 55549102981 scopus 로고    scopus 로고
    • Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience
    • Hansen CR, Pressler T, Høiby N. Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience. J Cyst Fibros. 2008;7(6): 523–530.
    • (2008) J Cyst Fibros , vol.7 , Issue.6 , pp. 523-530
    • Hansen, C.R.1    Pressler, T.2    Høiby, N.3
  • 6
    • 84907292321 scopus 로고    scopus 로고
    • An outbreak of extremely drug-resistant Pseudomonas aeruginosa in a tertiary care pediatric hospital in Italy
    • Ciofi Degli AM, Bernaschi P, Carletti M, et al. An outbreak of extremely drug-resistant Pseudomonas aeruginosa in a tertiary care pediatric hospital in Italy. BMC Infect Dis. 2014;14:494.
    • (2014) BMC Infect Dis , vol.14 , pp. 494
    • Ciofi Degli, A.M.1    Bernaschi, P.2    Carletti, M.3
  • 7
    • 79952999910 scopus 로고    scopus 로고
    • New treatment options against gram-negative organisms
    • Bassetti M, Ginocchio F, Mikulska M. New treatment options against gram-negative organisms. Crit Care. 2011;15(2):215.
    • (2011) Crit Care , vol.15 , Issue.2 , pp. 215
    • Bassetti, M.1    Ginocchio, F.2    Mikulska, M.3
  • 8
    • 84866602844 scopus 로고    scopus 로고
    • Antibacterial efficacy of inhaled squalamine in a rat model of chronic Pseudomonas aeruginosa pneumonia
    • Hraiech S, Brégeon F, Brunel JM, et al. Antibacterial efficacy of inhaled squalamine in a rat model of chronic Pseudomonas aeruginosa pneumonia. J Antimicrob Chemother. 2012;67(10):2452–2458.
    • (2012) J Antimicrob Chemother , vol.67 , Issue.10 , pp. 2452-2458
    • Hraiech, S.1    Brégeon, F.2    Brunel, J.M.3
  • 9
    • 84908583990 scopus 로고    scopus 로고
    • Inhaled lactonase reduces Pseudomonas aeruginosa quorum sensing and mortality in rat pneumonia
    • Hraiech S, Hiblot J, Lafleur J, et al. Inhaled lactonase reduces Pseudomonas aeruginosa quorum sensing and mortality in rat pneumonia. PLoS One. 2014;9(10):e107125.
    • (2014) Plos One , vol.9 , Issue.10
    • Hraiech, S.1    Hiblot, J.2    Lafleur, J.3
  • 10
    • 84867115760 scopus 로고    scopus 로고
    • Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis
    • Hurley MN, Cámara M, Smyth AR. Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. Eur Respir J. 2012;40(4):1014–1023.
    • (2012) Eur Respir J , vol.40 , Issue.4 , pp. 1014-1023
    • Hurley, M.N.1    Cámara, M.2    Smyth, A.R.3
  • 11
    • 79958774887 scopus 로고    scopus 로고
    • Bacteriophages for the treatment of Pseudomonas aeruginosa infections
    • Harper DR, Enright MC. Bacteriophages for the treatment of Pseudomonas aeruginosa infections. J Appl Microbiol. 2011;111(1):1–7.
    • (2011) J Appl Microbiol , vol.111 , Issue.1 , pp. 1-7
    • Harper, D.R.1    Enright, M.C.2
  • 12
    • 84920496550 scopus 로고    scopus 로고
    • Effectiveness of bacteriophages in the sputum of cystic fibrosis patients
    • Saussereau E, Vachier I, Chiron R, et al. Effectiveness of bacteriophages in the sputum of cystic fibrosis patients. Clin Microbiol Infect. 2014;20(12):O983–O990.
    • (2014) Clin Microbiol Infect , vol.20 , Issue.12 , pp. O983-O990
    • Saussereau, E.1    Vachier, I.2    Chiron, R.3
  • 13
    • 84862860490 scopus 로고    scopus 로고
    • Phage therapy – history from Twort and d’Herelle through Soviet experience to current approaches
    • Chanishvili N. Phage therapy – history from Twort and d’Herelle through Soviet experience to current approaches. Adv Virus Res. 2012;83:3–40.
    • (2012) Adv Virus Res , vol.83 , pp. 3-40
    • Chanishvili, N.1
  • 14
    • 85047104395 scopus 로고    scopus 로고
    • Experimental phage therapy of burn wound infection: Difficult first steps
    • Rose T, Verbeken G, Vos DD, et al. Experimental phage therapy of burn wound infection: difficult first steps. Int J Burns Trauma. 2014;4(2): 66–73.
    • (2014) Int J Burns Trauma , vol.4 , Issue.2 , pp. 66-73
    • Rose, T.1    Verbeken, G.2    Vos, D.D.3
  • 16
    • 68349154135 scopus 로고    scopus 로고
    • A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistant Pseudomonas aeruginosa; a preliminary report of efficacy
    • Wright A, Hawkins CH, Anggård EE, Harper DR. A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistant Pseudomonas aeruginosa; a preliminary report of efficacy. Clin Otolaryngol. 2009;34(4):349–357.
    • (2009) Clin Otolaryngol , vol.34 , Issue.4 , pp. 349-357
    • Wright, A.1    Hawkins, C.H.2    Anggård, E.E.3    Harper, D.R.4
  • 17
    • 84901948706 scopus 로고    scopus 로고
    • Phage therapy gets revitalized
    • Reardon S. Phage therapy gets revitalized. Nature. 2014;510(7503): 15–16.
    • (2014) Nature , vol.510 , Issue.7503 , pp. 15-16
    • Reardon, S.1
  • 18
    • 21744449475 scopus 로고    scopus 로고
    • [Epidemiology of nosocomial infections due to Pseudomonas aeruginosa, Burkholderia cepacia and Stenotrophomonas maltophilia.]
    • French
    • Berthelot P, Grattard F, Mallaval FO, Ros A, Lucht F, Pozzetto B. [Epidemiology of nosocomial infections due to Pseudomonas aeruginosa, Burkholderia cepacia and Stenotrophomonas maltophilia.] Pathol Biol (Paris). 2005;53(6):341–348. French.
    • (2005) Pathol Biol (Paris). , vol.53 , Issue.6 , pp. 341-348
    • Berthelot, P.1    Grattard, F.2    Mallaval, F.O.3    Ros, A.4    Lucht, F.5    Pozzetto, B.6
  • 19
    • 0037129218 scopus 로고    scopus 로고
    • Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation
    • Drenkard E, Ausubel FM. Pseudomonas biofilm formation and antibiotic resistance are linked to phenotypic variation. Nature. 2002;416(6882):740–743.
    • (2002) Nature , vol.416 , Issue.6882 , pp. 740-743
    • Drenkard, E.1    Ausubel, F.M.2
  • 20
    • 0033591467 scopus 로고    scopus 로고
    • Bacterial biofilms: A common cause of persistent infections
    • Costerton JW, Stewart PS, Greenberg EP. Bacterial biofilms: a common cause of persistent infections. Science. 1999;284(5418):1318–1322.
    • (1999) Science , vol.284 , Issue.5418 , pp. 1318-1322
    • Costerton, J.W.1    Stewart, P.S.2    Greenberg, E.P.3
  • 21
    • 0026649046 scopus 로고
    • Pseudomonas aeruginosa biofilm as a diffusion barrier to piperacillin
    • Hoyle BD, Alcantara J, Costerton JW. Pseudomonas aeruginosa biofilm as a diffusion barrier to piperacillin. Antimicrob Agents Chemother. 1992;36(9):2054–2056.
    • (1992) Antimicrob Agents Chemother , vol.36 , Issue.9 , pp. 2054-2056
    • Hoyle, B.D.1    Alcantara, J.2    Costerton, J.W.3
  • 22
    • 33845607284 scopus 로고    scopus 로고
    • Persister cells, dormancy and infectious disease
    • Lewis K. Persister cells, dormancy and infectious disease. Nat Rev Microbiol. 2007;5(1):48–56.
    • (2007) Nat Rev Microbiol , vol.5 , Issue.1 , pp. 48-56
    • Lewis, K.1
  • 23
    • 84886045100 scopus 로고    scopus 로고
    • Antimicrobial tolerance of Pseudomonas aeruginosa biofilms is activated during an early developmental stage and requires the two-component hybrid SagS
    • Gupta K, Marques CN, Petrova OE, Sauer K. Antimicrobial tolerance of Pseudomonas aeruginosa biofilms is activated during an early developmental stage and requires the two-component hybrid SagS. J Bacteriol. 2013;195(21):4975–4987.
    • (2013) J Bacteriol , vol.195 , Issue.21 , pp. 4975-4987
    • Gupta, K.1    Marques, C.N.2    Petrova, O.E.3    Sauer, K.4
  • 24
    • 84882642002 scopus 로고    scopus 로고
    • Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia
    • Doehn JM, Fischer K, Reppe K, et al. Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia. J Antimicrob Chemother. 2013;68(9):2111–2117.
    • (2013) J Antimicrob Chemother , vol.68 , Issue.9 , pp. 2111-2117
    • Doehn, J.M.1    Fischer, K.2    Reppe, K.3
  • 25
    • 34250892577 scopus 로고    scopus 로고
    • Bacteriophages: An appraisal of their role in the treatment of bacterial infections
    • Hanlon GW. Bacteriophages: an appraisal of their role in the treatment of bacterial infections. Int J Antimicrob Agents. 2007;30(2):118–128.
    • (2007) Int J Antimicrob Agents , vol.30 , Issue.2 , pp. 118-128
    • Hanlon, G.W.1
  • 26
    • 77950166515 scopus 로고    scopus 로고
    • Phage therapy in clinical practice: Treatment of human infections
    • Kutter E, De Vos D, Gvasalia G, et al. Phage therapy in clinical practice: treatment of human infections. Curr Pharm Biotechnol. 2010;11(1): 69–86.
    • (2010) Curr Pharm Biotechnol , vol.11 , Issue.1 , pp. 69-86
    • Kutter, E.1    De Vos, D.2    Gvasalia, G.3
  • 27
    • 0026056218 scopus 로고
    • Morphology of Pseudomonas aeruginosa phages from the sputum of cystic fibrosis patients and from the phage typing set. An electron microscopy study
    • Ojeniyi B, Birch-Andersen A, Mansa B, Rosdahl VT, Høiby N. Morphology of Pseudomonas aeruginosa phages from the sputum of cystic fibrosis patients and from the phage typing set. An electron microscopy study. APMIS. 1991;99(10):925–930.
    • (1991) APMIS. , vol.99 , Issue.10 , pp. 925-930
    • Ojeniyi, B.1    Birch-Andersen, A.2    Mansa, B.3    Rosdahl, V.T.4    Høiby, N.5
  • 28
    • 84876548481 scopus 로고    scopus 로고
    • The susceptibility of Pseudomonas aeruginosa strains from cystic fibrosis patients to bacteriophages
    • Essoh C, Blouin Y, Loukou G, et al. The susceptibility of Pseudomonas aeruginosa strains from cystic fibrosis patients to bacteriophages. PLoS One. 2013;8(4):e60575.
    • (2013) Plos One , vol.8 , Issue.4 , pp. e60575
    • Essoh, C.1    Blouin, Y.2    Loukou, G.3
  • 29
    • 77954706988 scopus 로고    scopus 로고
    • Bacteriophages of Pseudomonas
    • Ceyssens PJ, Lavigne R. Bacteriophages of Pseudomonas. Future Microbiol. 2010;5(7):1041–1055.
    • (2010) Future Microbiol , vol.5 , Issue.7 , pp. 1041-1055
    • Ceyssens, P.J.1    Lavigne, R.2
  • 30
    • 84864387005 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa population structure revisited under environmental focus: Impact of water quality and phage pressure
    • Selezska K, Kazmierczak M, Müsken M, et al. Pseudomonas aeruginosa population structure revisited under environmental focus: impact of water quality and phage pressure. Environ Microbiol. 2012;14(8): 1952–1967.
    • (2012) Environ Microbiol , vol.14 , Issue.8 , pp. 1952-1967
    • Selezska, K.1    Kazmierczak, M.2    Müsken, M.3
  • 31
    • 84884373003 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa adaptation to lungs of cystic fibrosis patients leads to lowered resistance to phage and protist enemies
    • Friman VP, Ghoul M, Molin S, Johansen HK, Buckling A. Pseudomonas aeruginosa adaptation to lungs of cystic fibrosis patients leads to lowered resistance to phage and protist enemies. PLoS One. 2013;8(9): e75380.
    • (2013) Plos One , vol.8 , Issue.9 , pp. e75380
    • Friman, V.P.1    Ghoul, M.2    Molin, S.3    Johansen, H.K.4    Buckling, A.5
  • 32
    • 84884228187 scopus 로고    scopus 로고
    • Impaired virulence and fitness of a colistin-resistant clinical isolate of Acinetobacter baumannii in a rat model of pneumonia
    • Hraiech S, Roch A, Lepidi H, et al. Impaired virulence and fitness of a colistin-resistant clinical isolate of Acinetobacter baumannii in a rat model of pneumonia. Antimicrob Agents Chemother. 2013;57(10):5120–5121.
    • (2013) Antimicrob Agents Chemother , vol.57 , Issue.10 , pp. 5120-5121
    • Hraiech, S.1    Roch, A.2    Lepidi, H.3
  • 33
    • 84859375251 scopus 로고    scopus 로고
    • The costs of evolving resistance in heterogeneous parasite environments
    • Koskella B, Lin DM, Buckling A, Thompson JN. The costs of evolving resistance in heterogeneous parasite environments. Proc Biol Sci. 2012; 279(1735):1896–1903.
    • (2012) Proc Biol Sci , vol.279 , Issue.1735 , pp. 1896-1903
    • Koskella, B.1    Lin, D.M.2    Buckling, A.3    Thompson, J.N.4
  • 34
    • 84866504626 scopus 로고    scopus 로고
    • Differential infection properties of three inducible prophages from an epidemic strain of Pseudomonas aeruginosa
    • James CE, Fothergill JL, Kalwij H, et al. Differential infection properties of three inducible prophages from an epidemic strain of Pseudomonas aeruginosa. BMC Microbiol. 2012;12:216.
    • (2012) BMC Microbiol , vol.12 , pp. 216
    • James, C.E.1    Fothergill, J.L.2    Kalwij, H.3
  • 35
    • 0025114008 scopus 로고
    • Phage-conversion of cytotoxin production in Pseudomonas aeruginosa
    • Hayashi T, Baba T, Matsumoto H, Terawaki Y. Phage-conversion of cytotoxin production in Pseudomonas aeruginosa. Mol Microbiol. 1990; 4(10):1703–1709.
    • (1990) Mol Microbiol , vol.4 , Issue.10 , pp. 1703-1709
    • Hayashi, T.1    Baba, T.2    Matsumoto, H.3    Terawaki, Y.4
  • 36
    • 61449134105 scopus 로고    scopus 로고
    • Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa
    • Winstanley C, Langille MG, Fothergill JL, et al. Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa. Genome Res. 2009;19(1):12–23.
    • (2009) Genome Res , vol.19 , Issue.1 , pp. 12-23
    • Winstanley, C.1    Langille, M.G.2    Fothergill, J.L.3
  • 37
    • 73849146761 scopus 로고    scopus 로고
    • Bacteriophage cocktail for the prevention of biofilm formation by Pseudomonas aeruginosa on catheters in an in vitro model system
    • Fu W, Forster T, Mayer O, Curtin JJ, Lehman SM, Donlan RM. Bacteriophage cocktail for the prevention of biofilm formation by Pseudomonas aeruginosa on catheters in an in vitro model system. Antimicrob Agents Chemother. 2010;54(1):397–404.
    • (2010) Antimicrob Agents Chemother , vol.54 , Issue.1 , pp. 397-404
    • Fu, W.1    Forster, T.2    Mayer, O.3    Curtin, J.J.4    Lehman, S.M.5    Donlan, R.M.6
  • 38
    • 0035377204 scopus 로고    scopus 로고
    • Reduction in exopolysaccharide viscosity as an aid to bacteriophage penetration through Pseudomonas aeruginosa biofilms
    • Hanlon GW, Denyer SP, Olliff CJ, Ibrahim LJ. Reduction in exopolysaccharide viscosity as an aid to bacteriophage penetration through Pseudomonas aeruginosa biofilms. Appl Environ Microbiol. 2001; 67(6):2746–2753.
    • (2001) Appl Environ Microbiol , vol.67 , Issue.6 , pp. 2746-2753
    • Hanlon, G.W.1    Denyer, S.P.2    Olliff, C.J.3    Ibrahim, L.J.4
  • 40
    • 0035029378 scopus 로고    scopus 로고
    • Biofilms and device-associated infections
    • Donlan RM. Biofilms and device-associated infections. Emerg Infect Dis. 2001;7(2):277–281.
    • (2001) Emerg Infect Dis , vol.7 , Issue.2 , pp. 277-281
    • Donlan, R.M.1
  • 41
    • 0034641962 scopus 로고    scopus 로고
    • Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms
    • Singh PK, Schaefer AL, Parsek MR, Moninger TO, Welsh MJ, Greenberg EP. Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms. Nature. 2000; 407(6805):762–764.
    • (2000) Nature , vol.407 , Issue.6805 , pp. 762-764
    • Singh, P.K.1    Schaefer, A.L.2    Parsek, M.R.3    Moninger, T.O.4    Welsh, M.J.5    Greenberg, E.P.6
  • 42
    • 79952108584 scopus 로고    scopus 로고
    • Structural changes induced by a lytic bacteriophage make ciprofloxacin effective against older biofilm of Klebsiella pneumoniae
    • Verma V, Harjai K, Chhibber S. Structural changes induced by a lytic bacteriophage make ciprofloxacin effective against older biofilm of Klebsiella pneumoniae. Biofouling. 2010;26(6):729–737.
    • (2010) Biofouling , vol.26 , Issue.6 , pp. 729-737
    • Verma, V.1    Harjai, K.2    Chhibber, S.3
  • 43
    • 74049108861 scopus 로고    scopus 로고
    • Bacteriophage-derived enzyme that depolymerizes the alginic acid capsule associated with cystic fibrosis isolates of Pseudomonas aeruginosa
    • Glonti T, Chanishvili N, Taylor PW. Bacteriophage-derived enzyme that depolymerizes the alginic acid capsule associated with cystic fibrosis isolates of Pseudomonas aeruginosa. J Appl Microbiol. 2010;108(2): 695–702.
    • (2010) J Appl Microbiol , vol.108 , Issue.2 , pp. 695-702
    • Glonti, T.1    Chanishvili, N.2    Taylor, P.W.3
  • 45
    • 63849290890 scopus 로고    scopus 로고
    • Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy
    • Lu TK, Collins JJ. Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proc Natl Acad Sci U S A. 2009; 106(12):4629–4634.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.12 , pp. 4629-4634
    • Lu, T.K.1    Collins, J.J.2
  • 46
    • 84866032343 scopus 로고    scopus 로고
    • Evolutionary dynamics of separate and combined exposure of Pseudomonas fluorescens SBW25 to antibiotics and bacteriophage
    • Escobar-Páramo P, Gougat-Barbera C, Hochberg ME. Evolutionary dynamics of separate and combined exposure of Pseudomonas fluorescens SBW25 to antibiotics and bacteriophage. Evol Appl. 2012; 5(6):583–592.
    • (2012) Evol Appl , vol.5 , Issue.6 , pp. 583-592
    • Escobar-Páramo, P.1    Gougat-Barbera, C.2    Hochberg, M.E.3
  • 47
    • 84907916701 scopus 로고    scopus 로고
    • A window of opportunity to control the bacterial pathogen Pseudomonas aeruginosa combining antibiotics and phages
    • Torres-Barceló C, Arias-Sánchez FI, Vasse M, Ramsayer J, Kaltz O, Hochberg ME. A window of opportunity to control the bacterial pathogen Pseudomonas aeruginosa combining antibiotics and phages. PLoS One. 2014;9(9):e106628.
    • (2014) Plos One , vol.9 , Issue.9
    • Torres-Barceló, C.1    Arias-Sánchez, F.I.2    Vasse, M.3    Ramsayer, J.4    Kaltz, O.5    Hochberg, M.E.6
  • 48
    • 84908237470 scopus 로고    scopus 로고
    • Effect of bacteriophage infection in combination with tobramycin on the emergence of resistance in Escherichia coli and Pseudomonas aeruginosa biofilms
    • Coulter LB, McLean RJ, Rohde RE, Aron GM. Effect of bacteriophage infection in combination with tobramycin on the emergence of resistance in Escherichia coli and Pseudomonas aeruginosa biofilms. Viruses. 2014;6(10):3778–3786.
    • (2014) Viruses , vol.6 , Issue.10 , pp. 3778-3786
    • Coulter, L.B.1    McLean, R.J.2    Rohde, R.E.3    Aron, G.M.4
  • 49
    • 84905898055 scopus 로고    scopus 로고
    • Inhibition of biofilm formation by T7 bacteriophages producing quorum-quenching enzymes
    • Pei R, Lamas-Samanamud GR. Inhibition of biofilm formation by T7 bacteriophages producing quorum-quenching enzymes. Appl Environ Microbiol. 2014;80(17):5340–5348.
    • (2014) Appl Environ Microbiol , vol.80 , Issue.17 , pp. 5340-5348
    • Pei, R.1    Lamas-Samanamud, G.R.2
  • 50
    • 84862888459 scopus 로고    scopus 로고
    • Phage as a modulator of immune responses: Practical implications for phage therapy
    • Górski A, Międzybrodzki R, Borysowski J, et al. Phage as a modulator of immune responses: practical implications for phage therapy. Adv Virus Res. 2012;83:41–71.
    • (2012) Adv Virus Res , vol.83 , pp. 41-71
    • Górski, A.1    Międzybrodzki, R.2    Borysowski, J.3
  • 52
    • 0041736230 scopus 로고    scopus 로고
    • Evaluation of aerosol spray and intramuscular injection of bacteriophage to treat an Escherichia coli respiratory infection
    • Huff WE, Huff GR, Rath NC, Balog JM, Donoghue AM. Evaluation of aerosol spray and intramuscular injection of bacteriophage to treat an Escherichia coli respiratory infection. Poult Sci. 2003;82(7): 1108–1112.
    • (2003) Poult Sci , vol.82 , Issue.7 , pp. 1108-1112
    • Huff, W.E.1    Huff, G.R.2    Rath, N.C.3    Balog, J.M.4    Donoghue, A.M.5
  • 53
    • 77749315460 scopus 로고    scopus 로고
    • Bacteriophages can treat and prevent Pseudomonas aeruginosa lung infections
    • Debarbieux L, Leduc D, Maura D, et al. Bacteriophages can treat and prevent Pseudomonas aeruginosa lung infections. J Infect Dis. 2010; 201(7):1096–1104.
    • (2010) J Infect Dis , vol.201 , Issue.7 , pp. 1096-1104
    • Debarbieux, L.1    Leduc, D.2    Maura, D.3
  • 54
    • 79951928650 scopus 로고    scopus 로고
    • Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: First steps towards treatment and prevention
    • Morello E, Saussereau E, Maura D, Huerre M, Touqui L, Debarbieux L. Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and prevention. PLoS One. 2011;6(2):e16963.
    • (2011) Plos One , vol.6 , Issue.2 , pp. e16963
    • Morello, E.1    Saussereau, E.2    Maura, D.3    Huerre, M.4    Touqui, L.5    Debarbieux, L.6
  • 55
    • 84860511608 scopus 로고    scopus 로고
    • Bacteriophages φMR299-2 and φNH-4 can eliminate Pseudomonas aeruginosa in the murine lung and on cystic fibrosis lung airway cells
    • Alemayehu D, Casey PG, McAuliffe O, et al. Bacteriophages φMR299-2 and φNH-4 can eliminate Pseudomonas aeruginosa in the murine lung and on cystic fibrosis lung airway cells. MBio. 2012;3(2):e00029–12.
    • (2012) Mbio , vol.3 , Issue.2 , pp. e00029-e00712
    • Alemayehu, D.1    Casey, P.G.2    McAuliffe, O.3
  • 56
    • 84887439648 scopus 로고    scopus 로고
    • Predicting in vivo efficacy of therapeutic bacteriophages used to treat pulmonary infections
    • Henry M, Lavigne R, Debarbieux L. Predicting in vivo efficacy of therapeutic bacteriophages used to treat pulmonary infections. Antimicrob Agents Chemother. 2013;57(12):5961–5968.
    • (2013) Antimicrob Agents Chemother , vol.57 , Issue.12 , pp. 5961-5968
    • Henry, M.1    Lavigne, R.2    Debarbieux, L.3
  • 57
    • 84936884330 scopus 로고    scopus 로고
    • Bacteriophage-Loaded Nanostructured Lipid Carrier: Improved Pharmacokinetics Mediates Effective Resolution of Klebsiella pneumoniae-Induced Lobar Pneumonia
    • Singla S, Harjai K, Katare OP, Chhibber S. Bacteriophage-Loaded Nanostructured Lipid Carrier: Improved Pharmacokinetics Mediates Effective Resolution of Klebsiella pneumoniae-Induced Lobar Pneumonia. J Infect Dis. 2015. Epub January 20.
    • (2015) J Infect Dis
    • Singla, S.1    Harjai, K.2    Katare, O.P.3    Chhibber, S.4
  • 58
    • 75649121887 scopus 로고    scopus 로고
    • Efficacy of bacteriophage therapy in a model of Burkholderia cenocepacia pulmonary infection
    • Carmody LA, Gill JJ, Summer EJ, et al. Efficacy of bacteriophage therapy in a model of Burkholderia cenocepacia pulmonary infection. J Infect Dis. 2010;201(2):264–271.
    • (2010) J Infect Dis , vol.201 , Issue.2 , pp. 264-271
    • Carmody, L.A.1    Gill, J.J.2    Summer, E.J.3
  • 59
    • 57749185051 scopus 로고    scopus 로고
    • Therapeutic potential of bacteriophage in treating Klebsiella pneumoniae B5055-mediated lobar pneumonia in mice
    • Chhibber S, Kaur S, Kumari S. Therapeutic potential of bacteriophage in treating Klebsiella pneumoniae B5055-mediated lobar pneumonia in mice. J Med Microbiol. 2008;57(Pt 12):1508–1513.
    • (2008) J Med Microbiol , vol.57 , Issue.12 , pp. 1508-1513
    • Chhibber, S.1    Kaur, S.2    Kumari, S.3
  • 60
    • 84903184886 scopus 로고    scopus 로고
    • Aerosol phage therapy efficacy in Burkholderia cepacia complex respiratory infections
    • Semler DD, Goudie AD, Finlay WH, Dennis JJ. Aerosol phage therapy efficacy in Burkholderia cepacia complex respiratory infections. Antimicrob Agents Chemother. 2014;58(7):4005–4013.
    • (2014) Antimicrob Agents Chemother , vol.58 , Issue.7 , pp. 4005-4013
    • Semler, D.D.1    Goudie, A.D.2    Finlay, W.H.3    Dennis, J.J.4
  • 61
    • 77954645549 scopus 로고    scopus 로고
    • Detection and accurate identification of new or emerging bacteria in cystic fibrosis patients
    • Bittar F, Rolain JM. Detection and accurate identification of new or emerging bacteria in cystic fibrosis patients. Clin Microbiol Infect. 2010;16(7):809–820.
    • (2010) Clin Microbiol Infect , vol.16 , Issue.7 , pp. 809-820
    • Bittar, F.1    Rolain, J.M.2
  • 62
    • 79958142002 scopus 로고    scopus 로고
    • The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease
    • Zhou Z, Duerr J, Johannesson B, et al. The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease. J Cyst Fibros. 2011;10 Suppl 2:S172–S182.
    • (2011) J Cyst Fibros , vol.10 , Issue.2 , pp. S172-S182
    • Zhou, Z.1    Duerr, J.2    Johannesson, B.3
  • 63
    • 64049105821 scopus 로고    scopus 로고
    • Quality-controlled small-scale production of a well-defined bacteriophage cocktail for use in human clinical trials
    • Merabishvili M, Pirnay JP, Verbeken G, et al. Quality-controlled small-scale production of a well-defined bacteriophage cocktail for use in human clinical trials. PLoS One. 2009;4(3):e4944.
    • (2009) Plos One , vol.4 , Issue.3 , pp. e4944
    • Merabishvili, M.1    Pirnay, J.P.2    Verbeken, G.3
  • 64
    • 52349124551 scopus 로고    scopus 로고
    • Phage therapy experience at the Eliava Institute
    • Kutateladze M, Adamia R. Phage therapy experience at the Eliava Institute. Med Mal Infect. 2008;38(8):426–430.
    • (2008) Med Mal Infect , vol.38 , Issue.8 , pp. 426-430
    • Kutateladze, M.1    Adamia, R.2
  • 65
    • 78149468115 scopus 로고    scopus 로고
    • Bacteriophages as potential new therapeutics to replace or supplement antibiotics
    • Kutateladze M, Adamia R. Bacteriophages as potential new therapeutics to replace or supplement antibiotics. Trends Biotechnol. 2010; 28(12):591–595.
    • (2010) Trends Biotechnol , vol.28 , Issue.12 , pp. 591-595
    • Kutateladze, M.1    Adamia, R.2
  • 66
    • 78650125693 scopus 로고    scopus 로고
    • In vitro lung delivery of bacteriophages KS4-M and ΦKZ using dry powder inhalers for treatment of Burkholderia cepacia complex and Pseudomonas aeruginosa infections in cystic fibrosis
    • Golshahi L, Lynch KH, Dennis JJ, Finlay WH. In vitro lung delivery of bacteriophages KS4-M and ΦKZ using dry powder inhalers for treatment of Burkholderia cepacia complex and Pseudomonas aeruginosa infections in cystic fibrosis. J Appl Microbiol. 2011;110(1):106–117.
    • (2011) J Appl Microbiol , vol.110 , Issue.1 , pp. 106-117
    • Golshahi, L.1    Lynch, K.H.2    Dennis, J.J.3    Finlay, W.H.4
  • 67
    • 80054699828 scopus 로고    scopus 로고
    • Bacteriophages as vehicles of the resistome in cystic fibrosis
    • Rolain JM, Fancello L, Desnues C, Raoult D. Bacteriophages as vehicles of the resistome in cystic fibrosis. J Antimicrob Chemother. 2011; 66(11):2444–2447.
    • (2011) J Antimicrob Chemother , vol.66 , Issue.11 , pp. 2444-2447
    • Rolain, J.M.1    Fancello, L.2    Desnues, C.3    Raoult, D.4
  • 68
    • 77049154774 scopus 로고
    • Growth and phage production of B. Megatherium. I. Growth of cells after infection with C phage. II. Rate of growth, phage yield, and RNA content of cells. III. Effect of various substances on growth rate and phage production
    • Northrop JH. Growth and phage production of B. megatherium. I. Growth of cells after infection with C phage. II. Rate of growth, phage yield, and RNA content of cells. III. Effect of various substances on growth rate and phage production. J Gen Physiol. 1953;36(4):581–599
    • (1953) J Gen Physiol , vol.36 , Issue.4 , pp. 581-599
    • Northrop, J.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.