Baicalin protects mice from aristolochic acid I-Induced kidney injury by induction of CYP1A through the aromatic hydrocarbon receptor

International Journal of Molecular Sciences

Volumn 16, Issue 7, 2015, Pages 16454-16468

  Wang, Ke ^a   Feng, Chenchen ^b   Li, Chenggang ^b   Yao, Jun ^b   Xie, Xiaofeng ^b   Gong, Likun ^b   Luan, Yang ^b   Xing, Guozhen ^b   Zhu, Xue ^a   Qi, Xinming ^b   Ren, Jin ^b  

^a BEIJING HOSPITAL   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Aristolochic acid; Aromatic hydrocarbon receptor; Baicalin; CYP1A; Kidney injury

Indexed keywords

3,4 DIMETHOXYFLAVONE; ARISTOLOCHIC ACID; AROMATIC HYDROCARBON RECEPTOR; BAICALIN; CREATININE; CYTOCHROME P450 1A; MESSENGER RNA; RESVERATROL; UNCLASSIFIED DRUG; ARISTOLOCHIC ACID I; CYTOCHROME P450 1A1; FLAVONOID; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; KIDNEY INJURY; LIVER CELL CULTURE; LUCIFERASE ASSAY; MALE; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PROTEIN EXPRESSION; QUANTITATIVE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SEQUENCE ANALYSIS; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING; XENOBIOTIC METABOLISM; ACUTE KIDNEY INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; BALKAN NEPHROPATHY; C57BL MOUSE; DRUG EFFECTS; GENETICS; HEP-G2 CELL LINE; HUMAN; KIDNEY; LIVER; METABOLISM;

MUS;

ACUTE KIDNEY INJURY; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARISTOLOCHIC ACIDS; BALKAN NEPHROPATHY; CYTOCHROME P-450 CYP1A1; FLAVONOIDS; HEP G2 CELLS; HUMANS; KIDNEY; LIVER; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, ARYL HYDROCARBON;

EID: 84937460137     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160716454     Document Type: Article

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