Tanshinone I protects mice from aristolochic acid I-induced kidney injury by induction of CYP1A

Environmental Toxicology and Pharmacology

Volumn 36, Issue 3, 2013, Pages 850-857

  Feng, Chenchen ^a   Xie, Xiaofeng ^a   Wu, Mengjun ^a   Li, Chunzhu ^a   Gao, Man ^a   Liu, Mingxia ^a   Qi, Xinming ^a   Ren, Jin ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Aristolochic acid; CYP1A; Kidney injury; Tanshinone I

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; MESSENGER RNA; TANSHINONE I;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; CYP1A1 GENE; CYP1A2 GENE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG HALF LIFE; DRUG STRUCTURE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VIVO STUDY; KIDNEY INJURY; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RENAL PROTECTION; TIME TO MAXIMUM PLASMA CONCENTRATION; TOXICITY TESTING; TRANSCRIPTION REGULATION;

ARISTOLOCHIC ACID; CYP1A; KIDNEY INJURY; TANSHINONE I;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AREA UNDER CURVE; ARISTOLOCHIC ACIDS; BLOOD CHEMICAL ANALYSIS; BLOTTING, WESTERN; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; DITERPENES, ABIETANE; ENZYME INDUCTION; KIDNEY; KIDNEY DISEASES; LIVER; LUCIFERASES; MALE; MICE; MICE, INBRED C57BL; PLASMIDS; REAL-TIME POLYMERASE CHAIN REACTION; RNA; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84883243836     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2013.07.017     Document Type: Article

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