Hyperhomocysteinemia inhibits satellite cell regenerative capacity through p38 alpha/beta MAPK signaling

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 309, Issue 2, 2015, Pages H325-H334

  Veeranki, Sudhakar ^a   Lominadze, David ^a   Tyagi, Suresh C ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

CBS; Hyperhomocysteinemia; P16; P21; P38 MAPK; Reactive oxygen species; Skeletal muscle

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CYSTATHIONINE BETA SYNTHASE; HOMOCYSTEINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE BETA; PROTEIN P16; PROTEIN P21; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL REGENERATION; COLONY FORMING UNIT; CONTROLLED STUDY; ENGRAFTMENT; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GASTROCNEMIUS MUSCLE; HYPERHOMOCYSTEINEMIA; IN VITRO STUDY; MALE; MOUSE; MUSCLE INJURY; MUSCLE MASS; MYOBLAST; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SARCOPENIA; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SKELETAL MUSCLE SATELLITE CELL; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; REGENERATION; TRANSPLANTATION;

ANIMALS; CELL LINE; CELL PROLIFERATION; CYSTATHIONINE BETA-SYNTHASE; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; HYPERHOMOCYSTEINEMIA; MAP KINASE SIGNALING SYSTEM; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SKELETAL; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; REACTIVE OXYGEN SPECIES; REGENERATION; SARCOPENIA; SATELLITE CELLS, SKELETAL MUSCLE;

EID: 84937458920     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00099.2015     Document Type: Article

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