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Volumn 24, Issue 7, 2015, Pages 1363-1377

Endothelial progenitor cells derived from wharton's jelly of human umbilical cord attenuate ischemic acute kidney injury by increasing vascularization and decreasing apoptosis, inflammation, and fibrosis

Author keywords

Acute kidney injury (AKI); Angiogenesis; Apoptosis; Endothelial progenitor cells (EPCs); Ischemia

Indexed keywords

CALVASCULIN; CHEMOKINE; CREATININE; CYTOKINE; MACROPHAGE INFLAMMATORY PROTEIN 2; NITROGEN; REACTIVE OXYGEN METABOLITE; UREA;

EID: 84937403998     PISSN: 09636897     EISSN: 15553892     Source Type: Journal    
DOI: 10.3727/096368914X681720     Document Type: Article
Times cited : (31)

References (45)
  • 1
    • 77949397760 scopus 로고    scopus 로고
    • Mediators of inflammation in acute kidney injury. Mediat
    • Akcay, A.; Nguyen, Q.; Edelstein, C. L. Mediators of inflammation in acute kidney injury. Mediat. Inflamm. 2009:137072; 2009.
    • (2009) Inflamm , pp. 2009
    • Akcay, A.1    Nguyen, Q.2    Edelstein, C.L.3
  • 2
    • 79959921363 scopus 로고    scopus 로고
    • Endothelial progenitor cells: A novel tool for the therapy of ischemic diseases
    • Alev, C.; Ii, M.; Asahara, T. Endothelial progenitor cells: A novel tool for the therapy of ischemic diseases. Antioxid. Redox. Signal. 15:949-965; 2011.
    • (2011) Antioxid. Redox. Signal , vol.15 , pp. 949-965
    • Alev, C.1    Ii, M.2    Asahara, T.3
  • 3
    • 72849107259 scopus 로고    scopus 로고
    • Immune mechanisms and novel pharmacological therapies of acute kidney injury
    • Bajwa, A.; Kinsey, G. R.; Okusa, M. D. Immune mechanisms and novel pharmacological therapies of acute kidney injury. Curr. Drug Targets 10:1196-1204; 2009.
    • (2009) Curr. Drug Targets , vol.10 , pp. 1196-1204
    • Bajwa, A.1    Kinsey, G.R.2    Okusa, M.D.3
  • 4
    • 34247632152 scopus 로고    scopus 로고
    • Stem cells and the regeneration of the aging cardiovascular system
    • Ballard, V. L. T.; Edelberg, J. M. Stem cells and the regeneration of the aging cardiovascular system. Circ. Res. 100:1116-1127; 2007.
    • (2007) Circ. Res , vol.100 , pp. 1116-1127
    • Ballard, V.1    Edelberg, J.M.2
  • 5
    • 34447526131 scopus 로고    scopus 로고
    • The endothelial cell in ischemic acute kidney injury: Implications for acute and chronic function
    • Basile, D. P. The endothelial cell in ischemic acute kidney injury: Implications for acute and chronic function. Kidney Int. 72:151-156; 2007.
    • (2007) Kidney Int , vol.72 , pp. 151-156
    • Basile, D.P.1
  • 6
    • 0035199934 scopus 로고    scopus 로고
    • Renal ischemic injury results in permanent damage to peritubu-lar capillaries and influences long-term function
    • Basile, D. P.; Donohoe, D.; Roethe, K.; Osborn, J. L. Renal ischemic injury results in permanent damage to peritubu-lar capillaries and influences long-term function. Am. J. Physiol. Renal Physiol. 281:F887-F899; 2001.
    • (2001) Am. J. Physiol. Renal Physiol , vol.281
    • Basile, D.P.1    Donohoe, D.2    Roethe, K.3    Osborn, J.L.4
  • 7
    • 84875587586 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from Wharton's Jelly of the umbilical cord: Biological properties and emerging clinical applications
    • Batsali, A. K.; Kastrinaki, M. C.; Papadaki, H. A.; Pontikoglou, C. Mesenchymal stem cells derived from Wharton's Jelly of the umbilical cord: Biological properties and emerging clinical applications. Curr. Stem Cell Res. Ther. 8:144-155; 2013.
    • (2013) Curr. Stem Cell Res. Ther , vol.8 , pp. 144-155
    • Batsali, A.K.1    Kastrinaki, M.C.2    Papadaki, H.A.3    Pontikoglou, C.4
  • 10
    • 0028022931 scopus 로고
    • Responses to hemorrhagic arterial pressure reduction in different ischemic renal failure models
    • Conger, J. D.; Schultz, M. F.; Miller, F.; Robinette, J. B. Responses to hemorrhagic arterial pressure reduction in different ischemic renal failure models. Kidney Int. 46:318-323; 1994.
    • (1994) Kidney Int , vol.46 , pp. 318-323
    • Conger, J.D.1    Schultz, M.F.2    Miller, F.3    Robinette, J.B.4
  • 11
    • 84867629610 scopus 로고    scopus 로고
    • The alleviation of acute and chronic kidney injury by human Wharton's jelly-derived mesenchymal stromal cells triggered by ischemia-reperfusion injury via an endocrine mechanism
    • Du, T.; Cheng, J.; Zhong, L.; Zhao, X. F.; Zhu, J.; Zhu, Y. J.; Liu, G. H. The alleviation of acute and chronic kidney injury by human Wharton's jelly-derived mesenchymal stromal cells triggered by ischemia-reperfusion injury via an endocrine mechanism. Cytotherapy 14:1215-1227; 2012.
    • (2012) Cytotherapy , vol.14 , pp. 1215-1227
    • Du, T.1    Cheng, J.2    Zhong, L.3    Zhao, X.F.4    Zhu, J.5    Zhu, Y.J.6    Liu, G.H.7
  • 12
    • 84866933457 scopus 로고    scopus 로고
    • Renoprotective effect of human umbilical cord-derived mesenchymal stem cells in immunodeficient mice suffering from acute kidney injury
    • Fang, T. C.; Pang, C. Y.; Chiu, S. C.; Ding, D. C.; Tsai, R. K. Renoprotective effect of human umbilical cord-derived mesenchymal stem cells in immunodeficient mice suffering from acute kidney injury. PLoS One 7:e46504; 2012.
    • (2012) Plos One , vol.7
    • Fang, T.C.1    Pang, C.Y.2    Chiu, S.C.3    Ding, D.C.4    Tsai, R.K.5
  • 13
    • 84874691322 scopus 로고    scopus 로고
    • Choice of cell-delivery route for successful cell transplantation therapy for the heart
    • Fukushima, S.; Sawa, Y.; Suzuki, K. Choice of cell-delivery route for successful cell transplantation therapy for the heart. Future Cardiol. 9:215-227; 2013.
    • (2013) Future Cardiol , vol.9 , pp. 215-227
    • Fukushima, S.1    Sawa, Y.2    Suzuki, K.3
  • 17
    • 79958794987 scopus 로고    scopus 로고
    • Apoptosis and acute kidney injury
    • Havasi, A.; Borkan, S. C. Apoptosis and acute kidney injury. Kidney Int. 80:29-40; 2011.
    • (2011) Kidney Int , vol.80 , pp. 29-40
    • Havasi, A.1    Borkan, S.C.2
  • 18
    • 78149396432 scopus 로고    scopus 로고
    • Functional module analysis reveals differential osteo-genic and stemness potentials in human mesenchymal stem cells from bone marrow and Wharton's jelly of umbilical cord
    • Hsieh, J. Y.; Fu, Y. S.; Chang, S. J.; Tsuang, Y. H.; Wang, H. W. Functional module analysis reveals differential osteo-genic and stemness potentials in human mesenchymal stem cells from bone marrow and Wharton's jelly of umbilical cord. Stem Cells Dev. 19:1895-1910;2010.
    • (2010) Stem Cells Dev , vol.19 , pp. 1895-1910
    • Hsieh, J.Y.1    Fu, Y.S.2    Chang, S.J.3    Tsuang, Y.H.4    Wang, H.W.5
  • 19
    • 84874833681 scopus 로고    scopus 로고
    • Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1
    • Hynes, B.; Kumar, A. H.; O'Sullivan, J.; Klein Buneker, C.; Leblond, A. L.; Weiss, S.; Schmeckpeper, J.; Martin, K.; Caplice, N. M. Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1. Eur. Heart J. 34:782-789; 2013.
    • (2013) Eur. Heart J , vol.34 , pp. 782-789
    • Hynes, B.1    Kumar, A.H.2    O'sullivan, J.3    Klein Buneker, C.4    Leblond, A.L.5    Weiss, S.6    Schmeckpeper, J.7    Martin, K.8    Caplice, N.M.9
  • 22
    • 77953022053 scopus 로고    scopus 로고
    • Mobilized human hematopoietic stem/ progenitor cells promote kidney repair after ischemia/ reperfusion injury
    • Li, B.; Cohen, A.; Hudson, T. E.; Motlagh, D.; Amrani, D. L.; Duffield, J. S. Mobilized human hematopoietic stem/ progenitor cells promote kidney repair after ischemia/ reperfusion injury. Circulation 121:2211-2220; 2010.
    • (2010) Circulation , vol.121 , pp. 2211-2220
    • Li, B.1    Cohen, A.2    Hudson, T.E.3    Motlagh, D.4    Amrani, D.L.5    Duffield, J.S.6
  • 23
    • 0037406831 scopus 로고    scopus 로고
    • Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice
    • Lin, F.; Cordes, K.; Li, L.; Hood, L.; Couser, W. G.; Shankland, S. J.; Igarashi, P. Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice. J. Am. Soc. Nephrol. 14:1188-1199; 2003.
    • (2003) J. Am. Soc. Nephrol , vol.14 , pp. 1188-1199
    • Lin, F.1    Cordes, K.2    Li, L.3    Hood, L.4    Couser, W.G.5    Shankland, S.J.6    Igarashi, P.7
  • 24
    • 77952673176 scopus 로고    scopus 로고
    • Transplantation of endothelial progenitor cells alleviates renal interstitial fibrosis in a mouse model of unilateral ureteral obstruction
    • Ma, Y. Y.; Sun, D.; Li, J.; Yin, Z. C. Transplantation of endothelial progenitor cells alleviates renal interstitial fibrosis in a mouse model of unilateral ureteral obstruction. Life Sci. 86:798-807; 2010.
    • (2010) Life Sci , vol.86 , pp. 798-807
    • Ma, Y.Y.1    Sun, D.2    Li, J.3    Yin, Z.C.4
  • 26
    • 0036323586 scopus 로고    scopus 로고
    • Long-term outcomes in acute renal failure patients treated with continuous renal replacement therapies
    • Morgera, S.; Kraft, A. K.; Siebert, G.; Luft, F. C.; Neumayer, H. H. Long-term outcomes in acute renal failure patients treated with continuous renal replacement therapies. Am. J. Kidney Dis. 40:275-279; 2002.
    • (2002) Am. J. Kidney Dis , vol.40 , pp. 275-279
    • Morgera, S.1    Kraft, A.K.2    Siebert, G.3    Luft, F.C.4    Neumayer, H.H.5
  • 27
    • 41649120196 scopus 로고    scopus 로고
    • Long-term outcomes after acute kidney injury. Crit
    • Morgera, S.; Schneider, M.; Neumayer, H. H. Long-term outcomes after acute kidney injury. Crit. Care Med. 36:S193-S197; 2008.
    • (2008) Care Med , vol.36
    • Morgera, S.1    Schneider, M.2    Neumayer, H.H.3
  • 29
    • 33644836279 scopus 로고    scopus 로고
    • Therapeutic use of stem and endothelial progenitor cells in acute renal injury
    • Patschan, D.; Plotkin, M.; Goligorsky, M. S. Therapeutic use of stem and endothelial progenitor cells in acute renal injury, Ca ira. Curr. Opin. Pharmacol. 6:176-183; 2006.
    • (2006) Ca Ira. Curr. Opin. Pharmacol , vol.6 , pp. 176-183
    • Patschan, D.1    Plotkin, M.2    Goligorsky, M.S.3
  • 30
    • 33749418694 scopus 로고    scopus 로고
    • Mesenchymal cells from adult kidney support angiogenesis and differentiate into multiple interstitial cell types including erythropoietin-producing fibroblasts
    • Plotkin, M. D.; Goligorsky, M. S. Mesenchymal cells from adult kidney support angiogenesis and differentiate into multiple interstitial cell types including erythropoietin-producing fibroblasts. Am. J. Physiol Renal Physiol. 291: 902-912; 2006.
    • (2006) Am. J. Physiol Renal Physiol , vol.291 , pp. 902-912
    • Plotkin, M.D.1    Goligorsky, M.S.2
  • 32
    • 0037240649 scopus 로고    scopus 로고
    • Searching for alternative sources of postnatal human mesenchymal stem cells: Candidate MSC-like cells from umbilical cord
    • Romanov, Y. A.; Svintsitskaya, V. A.; Smirnov, V. N. Searching for alternative sources of postnatal human mesenchymal stem cells: Candidate MSC-like cells from umbilical cord. Stem Cells 21:105-110; 2003.
    • (2003) Stem Cells , vol.21 , pp. 105-110
    • Romanov, Y.A.1    Svintsitskaya, V.A.2    Smirnov, V.N.3
  • 33
    • 79961238192 scopus 로고    scopus 로고
    • Ischemic kidney injury and mechanisms of tissue repair. Wiley Interdiscip
    • Sabbahy, M. E.; Vaidya, V. S. Ischemic kidney injury and mechanisms of tissue repair. Wiley Interdiscip. Rev. Syst. Biol. Med. 3:606-618; 2010.
    • (2010) Rev. Syst. Biol. Med , vol.3 , pp. 606-618
    • Sabbahy, M.E.1    Vaidya, V.S.2
  • 34
    • 0347918852 scopus 로고    scopus 로고
    • Age-dependent depression in circulating endothelial progenitor cells in patients undergoing coronary artery bypass grafting
    • Scheubel, R. J.; Zorn, H.; Silber, R. E.; Kuss, O.; Morawietz, H.; Holtz, J.; Simm, A. Age-dependent depression in circulating endothelial progenitor cells in patients undergoing coronary artery bypass grafting. J. Am. Coll. Cardiol. 42:2073-2080; 2003.
    • (2003) J. Am. Coll. Cardiol , vol.42 , pp. 2073-2080
    • Scheubel, R.J.1    Zorn, H.2    Silber, R.E.3    Kuss, O.4    Morawietz, H.5    Holtz, J.6    Simm, A.7
  • 35
    • 33646194030 scopus 로고    scopus 로고
    • Renal recovery from acute tubular necrosis requiring renal replacement therapy: A prospective study in critically ill patients
    • Schiffl, H. Renal recovery from acute tubular necrosis requiring renal replacement therapy: A prospective study in critically ill patients. Nephrol. Dial. Transplant. 21:1248-1252; 2006.
    • (2006) Nephrol. Dial. Transplant , vol.21 , pp. 1248-1252
    • Schiffl, H.1
  • 36
    • 84876905906 scopus 로고    scopus 로고
    • Endothelial progenitor cells derived from Wharton's jelly of the umbilical cord reduces ischemia-induced hind limb injury in diabetic mice by inducing HIF-1a/IL-8 expression
    • Shen, W. C.; Liang, C. J., Wu, V. C.; Wang, S. H.; Young, G. H.; Lai, I. R.; Chien, C. L.; Wang, S. M.; Wu, K. D.; Chen, Y. L. Endothelial progenitor cells derived from Wharton's jelly of the umbilical cord reduces ischemia-induced hind limb injury in diabetic mice by inducing HIF-1a/IL-8 expression. Stem Cells Dev. 22:1408-1418; 2013.
    • (2013) Stem Cells Dev , vol.22 , pp. 1408-1418
    • Shen, W.C.1    Liang, C.J.2    Wu, V.C.3    Wang, S.H.4    Young, G.H.5    Lai, I.R.6    Chien, C.L.7    Wang, S.M.8    Wu, K.D.9    Chen, Y.L.10
  • 37
    • 77954012344 scopus 로고    scopus 로고
    • Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase
    • Stroo, I.; Stokman, G.; Teske, G. J.; Raven, A.; Butter, L. M.; Florquin, S.; Leemans, J. C. Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase. Int. Immunol. 22:433-442; 2010.
    • (2010) Int. Immunol , vol.22 , pp. 433-442
    • Stroo, I.1    Stokman, G.2    Teske, G.J.3    Raven, A.4    Butter, L.M.5    Florquin, S.6    Leemans, J.C.7
  • 38
    • 80052434885 scopus 로고    scopus 로고
    • Wharton's Jelly stem cells: Future clinical applications
    • Taghizadeh, R. R.; Cetrulo, K. J.; Cetrulo, C. L. Wharton's Jelly stem cells: Future clinical applications. Placenta 32: S311-S315; 2011.
    • (2011) Placenta , vol.32
    • Taghizadeh, R.R.1    Cetrulo, K.J.2    Cetrulo, C.L.3
  • 39
    • 22944444547 scopus 로고    scopus 로고
    • Cord blood transplantation in adult patients
    • Tse, W.; Laughlin, M. Cord blood transplantation in adult patients. Cytotherapy 7:228-242; 2005.
    • (2005) Cytotherapy , vol.7 , pp. 228-242
    • Tse, W.1    Laughlin, M.2
  • 40
    • 0034175876 scopus 로고    scopus 로고
    • Apoptotic mechanisms in acute renal failure
    • Ueda, N.; Kaushal, G. P.; Shah, S. V. Apoptotic mechanisms in acute renal failure. Am. J. Med. 108:403-415; 2000.
    • (2000) Am. J. Med , vol.108 , pp. 403-415
    • Ueda, N.1    Kaushal, G.P.2    Shah, S.V.3
  • 42
    • 66349089605 scopus 로고    scopus 로고
    • Late outgrowth endothe- lial cells derived from Wharton Jelly in human umbilical cord reduce neointimal formation after vascular injury
    • Wang, S. H.; Lin, S. J.; Chen, Y. H.; Lin, F. Y.; Shih, J. C.; Wu, C. C.; Wu, H. L.; Chen, Y. L. Late outgrowth endothe- lial cells derived from Wharton Jelly in human umbilical cord reduce neointimal formation after vascular injury. Arterioscler. Thromb. Vasc. Biol. 29:816-822; 2009.
    • (2009) Arterioscler. Thromb. Vasc. Biol , vol.29 , pp. 816-822
    • Wang, S.H.1    Lin, S.J.2    Chen, Y.H.3    Lin, F.Y.4    Shih, J.C.5    Wu, C.C.6    Wu, H.L.7    Chen, Y.L.8
  • 44
    • 51849102512 scopus 로고    scopus 로고
    • Stem cells for kidney repair: Useful tool for acute renal failure?
    • Yokoo, T.; Kawamura, T.; Kobayashi, E. Stem cells for kidney repair: Useful tool for acute renal failure? Kidney Int. 74:847-849; 2008.
    • (2008) Kidney Int , vol.74 , pp. 847-849
    • Yokoo, T.1    Kawamura, T.2    Kobayashi, E.3
  • 45
    • 84856276113 scopus 로고    scopus 로고
    • Transient ureteral obstruction prevents against kidney ischemia/reperfusion injury via hypoxia-inducible factor (HIF)-2 activation
    • Zhang, S.; Han, C. H.; Chen, X. S.; Zhang, M.; Xu, L. M.; Zhang, J. J.; Xia, Q. Transient ureteral obstruction prevents against kidney ischemia/reperfusion injury via hypoxia-inducible factor (HIF)-2 activation. PLoS One 7:e29876; 2012.
    • (2012) Plos One , vol.7
    • Zhang, S.1    Han, C.H.2    Chen, X.S.3    Zhang, M.4    Xu, L.M.5    Zhang, J.J.6    Xia, Q.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.