Neural Correlates of the Cortisol Awakening Response in Humans

Neuropsychopharmacology

Volumn 40, Issue 9, 2015, Pages 2278-2285

  Boehringer, Andreas ^a   Tost, Heike ^a   Haddad, Leila ^a   Lederbogen, Florian ^a   Wüst, Stefan ^a,b   Schwarz, Emanuel ^a   Meyer Lindenberg, Andreas ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; OXYGEN;

ADULT; AGED; AROUSAL; ARTICLE; BRAIN FUNCTION; BRAIN SIZE; CONNECTOME; CORTISOL AWAKENING RESPONSE; DIASTOLIC BLOOD PRESSURE; ELECTROENCEPHALOGRAM; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; GRAY MATTER; HAMILTON DEPRESSION RATING SCALE; HUMAN; HUMAN EXPERIMENT; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; MENTAL DISEASE; MENTAL STRESS; NERVE CELL; NEUROPATHOLOGY; NORMAL HUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SEX DIFFERENCE; VOXEL BASED MORPHOMETRY; YOUNG ADULT; BLOOD; BLOOD PRESSURE; BRAIN; BRAIN MAPPING; CHEMISTRY; HEART RATE; IMAGE PROCESSING; METABOLISM; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PAIN MEASUREMENT; PATHOLOGY; PHYSIOLOGY; SALIVA; STATISTICS; TIME FACTOR; VASCULARIZATION; WAKEFULNESS;

ADULT; AGED; BLOOD PRESSURE; BRAIN; BRAIN MAPPING; FEMALE; HEART RATE; HUMANS; HYDROCORTISONE; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OXYGEN; PAIN MEASUREMENT; SALIVA; SEX FACTORS; STATISTICS AS TOPIC; STRESS, PSYCHOLOGICAL; TIME FACTORS; WAKEFULNESS; YOUNG ADULT;

EID: 84937164582     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2015.77     Document Type: Article

References (57)

1. Adam EK, Doane LD, Zinbarg RE, Mineka S, Craske MG, Griffith JW (2010). Prospective prediction of major depressive disorder from cortisol awakening responses in adolescence. Psychoneuroendocri-nology 35: 921-931.
2. Ahima RS, Harlan RE (1990). Charting of type II glucocorticoid receptor-like immunoreactivity in the rat central nervous system. Neuroscience 39: 579-604.
3. Akdeniz C, Tost H, Streit F, Haddad L, Wust S, Schafer A et al (2014). Neuroimaging evidence for a role of neural social stress processing in ethnic minority-associated environmental risk. JAMA Psychiatry 71: 672-680.
4. Almeida DM, Piazza JR, Stawski RS (2009). Interindividual differences and intraindividual variability in the cortisol awakening response: an examination of age and gender. Psychol Aging 24: 819-827.
5. Bartels M, Van den Berg M, Sluyter F, Boomsma DI, de Geus EJ (2003). Heritability of cortisol levels: review and simultaneous analysis of twin studies. Psychoneuroendocrinology 28: 121-137.
6. Bora E, Fornito A, Pantelis C, Yucel M (2012). Gray matter abnormalities in Major Depressive Disorder: a meta-analysis of voxel based morphometry studies. J Affect Disord 138: 9-18.
7. Boyle MP, Brewer JA, Funatsu M, Wozniak DF, Tsien JZ, Izumi Y et al (2005). Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior. Proc Natl Acad Sci USA 102: 473-478.
8. Bush G, Luu P, Posner MI (2000). Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 4: 215-222.
9. Chida Y, Steptoe A (2009). Cortisol awakening response and psychosocial factors: a systematic review and meta-analysis. Biol Psychol 80: 265-278.
10. Cohen RA, Grieve S, Hoth KF, Paul RH, Sweet L, Tate D et al (2006). Early life stress and morphometry of the adult anterior cingulate cortex and caudate nuclei. Biol Psychiatry 59: 975-982.
11. de Kloet CS, Vermetten E, Geuze E, Kavelaars A, Heijnen CJ, Westenberg HG (2006). Assessment of HPA-axis function in posttraumatic stress disorder: pharmacological and non-pharmacological challenge tests, a review. J Psychiatr Res 40: 550-567.
12. de Kloet ER, Joels M, Holsboer F (2005). Stress and the brain: from adaptation to disease. Nat Rev Neurosci 6: 463-475.
13. Dedovic K, Engert V, Duchesne A, Lue SD, Andrews J, Efanov SI et al (2010). Cortisol awakening response and hippocampal volume: vulnerability for major depressive disorder? Biol Psychiatry 68: 847-853.
14. Dedovic K, Renwick R, Mahani NK, Engert V, Lupien SJ, Pruessner JC (2005). The Montreal Imaging Stress Task: using functional imaging to investigate the effects of perceiving and processing psychosocial stress in the human brain. J Psychiatry Neurosci 30: 319-325.
15. Diorio D, Viau V, Meaney MJ (1993). The role of the medial pre-frontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress. J Neurosci 13: 3839-3847.
16. Dressendorfer RA, Kirschbaum C, Rohde W, Stahl F, Strasburger CJ (1992). Synthesis of a cortisol-biotin conjugate and evaluation as a tracer in an immunoassay for salivary cortisol measurement. J Steroid Biochem Mol Biol 43: 683-692.
17. Etkin A, Egner T, Kalisch R (2011). Emotional processing in anterior cingulate and medial prefrontal cortex. Trends Cogn Sci 15: 85-93.
18. Fusar-Poli P, Radua J, McGuire P, Borgwardt S (2012). Neuroana-tomical maps of psychosis onset: voxel-wise meta-analysis of antipsychotic-naive VBM studies. Schizophr Bull 38: 1297-1307.
19. Hamani C, Mayberg H, Stone S, Laxton A, Haber S, Lozano AM (2011). The subcallosal cingulate gyrus in the context of major depression. Biol Psychiatry 69: 301-308.
20. Hamilton M (1960). A rating scale for depression. J Neurol Neurosurg Psychiatry 23: 56-62.
21. Heim C, Nater UM, Maloney E, Boneva R, Jones JF, Reeves WC (2009). Childhood trauma and risk for chronic fatigue syndrome: association with neuroendocrine dysfunction. Arch Gen Psychiatry 66: 72-80.
22. Herman JP, Ostrander MM, Mueller NK, Figueiredo H (2005). Limbic system mechanisms of stress regulation: hypothalamo-pituitary-adrenocortical axis. Prog Neuropsychopharmacol Biol Psychiatry 29: 1201-1213.
23. Huber TJ, Issa K, Schik G, Wolf OT (2006). The cortisol awakening response is blunted in psychotherapy inpatients suffering from depression. Psychoneuroendocrinology 31: 900-904.
24. Joels M, Karst H, DeRijk R, de Kloet ER (2008). The coming out of the brain mineralocorticoid receptor. Trends Neurosci 31: 1-7.
25. Karl A, Schaefer M, Malta LS, Dorfel D, Rohleder N, Werner A (2006). A meta-analysis of structural brain abnormalities in PTSD. Neurosci Biobehav Rev 30: 1004-1031.
26. Kupper N, de Geus EJ, van den Berg M, Kirschbaum C, Boomsma DI, Willemsen G (2005). Familial influences on basal salivary cortisol in an adult population. Psychoneuroendocrinology 30: 857-868.
27. Lamers F, Vogelzangs N, Merikangas KR, de Jonge P, Beekman AT, Penninx BW (2013). Evidence for a differential role of HPA-axis function, inflammation and metabolic syndrome in melancholic versus atypical depression. Mol Psychiatry 18: 692-699.
28. Lederbogen F, Kirsch P, Haddad L, Streit F, Tost H, Schuch P et al (2011). City living and urban upbringing affect neural social stress processing in humans. Nature 474: 498-501.
29. Lohmann G, Hoehl S, Brauer J, Danielmeier C, Bornkessel-Schlesewsky I, Bahlmann J et al (2010). Setting the frame: the human brain activates a basic low-frequency network for language processing. Cereb Cortex 20: 1286-1292.
30. Lu S, Gao W, Wei Z, Wu W, Liao M, Ding Y et al (2013). Reduced cingulate gyrus volume associated with enhanced cortisol awakening response in young healthy adults reporting childhood trauma. PloS One 8: e69350.
31. Madsen KS, Jernigan TL, Iversen P, Frokjaer VG, Mortensen EL, Knudsen GM et al (2012). Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture. Psychiatry Res 201: 63-72.
32. Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH (2003). An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. NeuroImage 19: 1233-1239.
33. Mangold D, Wand G, Javors M, Mintz J (2010). Acculturation, childhood trauma and the cortisol awakening response in Mexican-American adults. Horm Behav 58: 637-646.
34. Mannie ZN, Harmer CJ, Cowen PJ (2007). Increased waking salivary cortisol levels in young people at familial risk of depression. Am J Psychiatry 164: 617-621.
35. Meyer-Lindenberg A, Buckholtz JW, Kolachana B, R Hariri A, Pezawas L, Blasi G et al (2006). Neural mechanisms of genetic risk for impulsivity and violence in humans. Proc Natl Acad Sci USA 103: 6269-6274.
36. Meyer-Lindenberg A, Tost H (2012). Neural mechanisms of social risk for psychiatric disorders. Nat Neurosci 15: 663-668.
37. Mondelli V, Dazzan P, Hepgul N, Di Forti M, Aas M, D'Albenzio A et al (2010). Abnormal cortisol levels during the day and cortisol awakening response in first-episode psychosis: the role of stress and of antipsychotic treatment. Schizophr Res 116: 234-242.
38. Pariante CM, Lightman SL (2008). The HPA axis in major depression: classical theories and new developments. Trends Neurosci 31: 464-468.
39. Patel PD, Lopez JF, Lyons DM, Burke S, Wallace M, Schatzberg AF (2000). Glucocorticoid and mineralocorticoid receptor mRNA expression in squirrel monkey brain. J Psychiatr Res 34: 383-392.
40. Pezawas L, Meyer-Lindenberg A, Drabant EM, Verchinski BA, Munoz KE, Kolachana BS et al (2005). 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nat Neurosci 8: 828-834.
41. Pruessner JC, Dedovic K, Khalili-Mahani N, Engert V, Pruessner M, Buss C et al (2008). Deactivation of the limbic system during acute psychosocial stress: evidence from positron emission tomography and functional magnetic resonance imaging studies. Biol Psychiatry 63: 234-240.
42. Pruessner JC, Wolf OT, Hellhammer DH, Buske-Kirschbaum A, von Auer K, Jobst S et al (1997). Free cortisol levels after awakening: a reliable biological marker for the assessment of adrenocortical activity. Life Sci 61: 2539-2549.
43. Pruessner M, Hellhammer DH, Pruessner JC, Lupien SJ (2003). Self-reported depressive symptoms and stress levels in healthy young men: associations with the cortisol response to awakening. Psychosom Med 65: 92-99.
44. Rosenkranz JA, Moore H, Grace AA (2003). The prefrontal cortex regulates lateral amygdala neuronal plasticity and responses to previously conditioned stimuli. J Neurosci 23: 11054-11064.
45. Schmidt-Reinwald A, Pruessner JC, Hellhammer DH, Federenko I, Rohleder N, Schurmeyer TH et al (1999). The cortisol response to awakening in relation to different challenge tests and a 12-hour cortisol rhythm. Life Sci 64: 1653-1660.
46. Stetler C, Miller GE (2005). Blunted cortisol response to awakening in mild to moderate depression: regulatory influences of sleep patterns and social contacts. J Abnorm Psychol 114: 697-705.
47. Thorn L, Hucklebridge F, Evans P, Clow A (2009). The cortisol awakening response, seasonality, stress and arousal: a study of trait and state influences. Psychoneuroendocrinology 34: 299-306.
48. Tost H, Meyer-Lindenberg A (2012). Puzzling over schizophrenia: schizophrenia, social environment and the brain. Nat Med 18: 211-213.
49. Ulrich-Lai YM, Herman JP (2009). Neural regulation of endocrine and autonomic stress responses. Nat Rev Neurosci 10: 397-409.
50. van Leeuwen N, Kumsta R, Entringer S, de Kloet ER, Zitman FG, DeRijk RH et al (2010). Functional mineralocorticoid receptor (MR) gene variation influences the cortisol awakening response after dexamethasone. Psychoneuroendocrinology 35: 339-349.
51. Vreeburg SA, Hoogendijk WJ, van Pelt J, Derijk RH, Verhagen JC, van Dyck R et al (2009). Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study. Arch Gen Psychiatry 66: 617-626.
52. Vrshek-Schallhorn S, Doane LD, Mineka S, Zinbarg RE, Craske MG, Adam EK (2013). The cortisol awakening response predicts major depression: predictive stability over a 4-year follow-up and effect of depression history. Psychol Med 43: 483-493.
53. Wessa M, Rohleder N, Kirschbaum C, Flor H (2006). Altered cortisol awakening response in posttraumatic stress disorder. Psychoneuroendocrinology 31: 209-215.
54. Wilhelm I, Born J, Kudielka BM, Schlotz W, Wust S (2007). Is the cortisol awakening rise a response to awakening? Psychoneur-oendocrinology 32: 358-366.
55. Worsley KJ, Marrett S, Neelin P, Vandal AC, Friston KJ, Evans AC (1996). A unified statistical approach for determining significant signals in images of cerebral activation. Hum Brain Mapp 4: 58-73.
56. Wust S, Federenko I, Hellhammer DH, Kirschbaum C (2000a). Genetic factors, perceived chronic stress, and the free cortisol response to awakening. Psychoneuroendocrinology 25: 707-720.
57. Wust S, Wolf J, Hellhammer DH, Federenko I, Schommer N, Kirschbaum C (2000b). The cortisol awakening response-normal values and confounds. Noise Health 2: 79-88.