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Volumn 33, Issue 16, 2015, Pages 1721-1728

Screening in GI cancers: The role of genetics

Author keywords

[No Author keywords available]

Indexed keywords

CANCER GENETICS; CANCER PREVENTION; CANCER SCREENING; COLORECTAL CANCER; COWDEN SYNDROME; DIGESTIVE SYSTEM CANCER; FAMILIAL CANCER; FAMILIAL COLON POLYPOSIS; FAMILY HISTORY; GENETIC PREDISPOSITION; GENETIC RISK; GENOMICS; GERMLINE MUTATION; HAMARTOMATOUS POLYPOSIS; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HIGH RISK PATIENT; HUMAN; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PATIENT IDENTIFICATION; PHENOTYPE; POLYPOSIS; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; STOMACH ADENOCARCINOMA; STOMACH CANCER; ANIMAL; EARLY DIAGNOSIS; GASTROINTESTINAL NEOPLASMS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETIC SCREENING; GENETICS; HEREDITY; PATHOLOGY; PEDIGREE; PERSONALIZED MEDICINE; PREDICTIVE VALUE; PROCEDURES; PROGNOSIS; RISK FACTOR;

EID: 84937150562     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2014.60.6764     Document Type: Review
Times cited : (24)

References (59)
  • 2
    • 84922879208 scopus 로고    scopus 로고
    • Molecular subtyping of colorectal cancer: Time to explore both intertumoral and intratumoral heterogeneity to evaluate patient outcome
    • Fearon ER, Carethers JM: Molecular subtyping of colorectal cancer: Time to explore both intertumoral and intratumoral heterogeneity to evaluate patient outcome. Gastroenterology 148:10-13, 2015
    • (2015) Gastroenterology , vol.148 , pp. 10-13
    • Fearon, E.R.1    Carethers, J.M.2
  • 3
    • 84899761198 scopus 로고    scopus 로고
    • American Society of Clinical Oncology expert statement: Collection and use of a cancer family history for oncology providers
    • Lu KH, Wood ME, Daniels M, et al: American Society of Clinical Oncology expert statement: Collection and use of a cancer family history for oncology providers. J Clin Oncol 32:833-840, 2014
    • (2014) J Clin Oncol , vol.32 , pp. 833-840
    • Lu, K.H.1    Wood, M.E.2    Daniels, M.3
  • 4
    • 57449097359 scopus 로고    scopus 로고
    • Feasibility of screening for Lynch syndrome among patients with colorectal cancer
    • Hampel H, Frankel WL, Martin E, et al: Feasibility of screening for Lynch syndrome among patients with colorectal cancer. J Clin Oncol 26:5783-5788, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 5783-5788
    • Hampel, H.1    Frankel, W.L.2    Martin, E.3
  • 6
    • 67449084400 scopus 로고    scopus 로고
    • Increase in incidence of colorectal cancer among young men and women in the United States
    • Siegel RL, Jemal A, Ward EM: Increase in incidence of colorectal cancer among young men and women in the United States. Cancer Epidemiol Biomarkers Prev 18:1695-1698, 2009
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 1695-1698
    • Siegel, R.L.1    Jemal, A.2    Ward, E.M.3
  • 7
    • 42949127635 scopus 로고    scopus 로고
    • Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: A joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology
    • Levin B, Lieberman DA, McFarland B, et al: Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: A joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. Gastroenterology 134:1570-1595, 2008
    • (2008) Gastroenterology , vol.134 , pp. 1570-1595
    • Levin, B.1    Lieberman, D.A.2    McFarland, B.3
  • 8
    • 0027942094 scopus 로고
    • A prospective study of family history and the risk of colorectal cancer
    • Fuchs CS, Giovannucci EL, Colditz GA, et al: A prospective study of family history and the risk of colorectal cancer. N Engl J Med 331:1669-1674, 1994
    • (1994) N Engl J Med , vol.331 , pp. 1669-1674
    • Fuchs, C.S.1    Giovannucci, E.L.2    Colditz, G.A.3
  • 9
    • 0025848680 scopus 로고
    • The international collaborative group on hereditary nonpolyposis colorectal cancer (ICG-HNPCC)
    • Vasen HF, Mecklin JP, Khan PM, et al: The international collaborative group on hereditary nonpolyposis colorectal cancer (ICG-HNPCC). Dis Colon Rectum 34:424-425, 1991
    • (1991) Dis Colon Rectum , vol.34 , pp. 424-425
    • Vasen, H.F.1    Mecklin, J.P.2    Khan, P.M.3
  • 10
    • 17944362664 scopus 로고    scopus 로고
    • Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer)
    • Hampel H, Frankel WL, Martin E, et al: Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer). N Engl J Med 352:1851-1860, 2005
    • (2005) N Engl J Med , vol.352 , pp. 1851-1860
    • Hampel, H.1    Frankel, W.L.2    Martin, E.3
  • 11
    • 10744233937 scopus 로고    scopus 로고
    • Revised Bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability
    • Umar A, Boland CR, Terdiman JP, et al: Revised Bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 96:261-268, 2004
    • (2004) J Natl Cancer Inst , vol.96 , pp. 261-268
    • Umar, A.1    Boland, C.R.2    Terdiman, J.P.3
  • 12
    • 33749066191 scopus 로고    scopus 로고
    • Prediction of germline mutations and cancer risk in the Lynch syndrome
    • Chen S, Wang W, Lee S, et al: Prediction of germline mutations and cancer risk in the Lynch syndrome. JAMA 296:1479-1487, 2006
    • (2006) JAMA , vol.296 , pp. 1479-1487
    • Chen, S.1    Wang, W.2    Lee, S.3
  • 13
    • 78650513224 scopus 로고    scopus 로고
    • The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history
    • Kastrinos F, Steyerberg EW, Mercado R, et al: The PREMM(1,2,6) model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history. Gastroenterology 140:73-81, 2011
    • (2011) Gastroenterology , vol.140 , pp. 73-81
    • Kastrinos, F.1    Steyerberg, E.W.2    Mercado, R.3
  • 14
    • 4444328981 scopus 로고    scopus 로고
    • Physician assessment of family cancer history and referral for genetic evaluation in colorectal cancer patients
    • Grover S, Stoffel EM, Bussone L, et al: Physician assessment of family cancer history and referral for genetic evaluation in colorectal cancer patients. Clin Gastroenterol Hepatol 2:813-819, 2004
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 813-819
    • Grover, S.1    Stoffel, E.M.2    Bussone, L.3
  • 15
    • 72449176846 scopus 로고    scopus 로고
    • Molecular origins of cancer: Molecular basis of colorectal cancer
    • Markowitz SD, Bertagnolli MM: Molecular origins of cancer: Molecular basis of colorectal cancer. N Engl J Med 361:2449-2460, 2009
    • (2009) N Engl J Med , vol.361 , pp. 2449-2460
    • Markowitz, S.D.1    Bertagnolli, M.M.2
  • 16
    • 0038002279 scopus 로고    scopus 로고
    • Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
    • Ribic CM, Sargent DJ, Moore MJ, et al: Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 349:247-257, 2003
    • (2003) N Engl J Med , vol.349 , pp. 247-257
    • Ribic, C.M.1    Sargent, D.J.2    Moore, M.J.3
  • 17
    • 78651241644 scopus 로고    scopus 로고
    • Colorectal cancer molecular biology moves into clinical practice
    • Pritchard CC, Grady WM: Colorectal cancer molecular biology moves into clinical practice. Gut 60:116-129, 2011
    • (2011) Gut , vol.60 , pp. 116-129
    • Pritchard, C.C.1    Grady, W.M.2
  • 18
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • Cancer Genome Atlas Network: Comprehensive molecular characterization of human colon and rectal cancer. Nature 487:330-337, 2012
    • (2012) Nature , vol.487 , pp. 330-337
    • Cancer Genome Atlas Network1
  • 19
    • 84873096362 scopus 로고    scopus 로고
    • Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas
    • Palles C, Cazier JB, Howarth KM, et al: Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nat Genet 45:136-144, 2013
    • (2013) Nat Genet , vol.45 , pp. 136-144
    • Palles, C.1    Cazier, J.B.2    Howarth, K.M.3
  • 20
    • 20544467125 scopus 로고    scopus 로고
    • Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: Correction for ascertainment
    • Quehenberger F, Vasen HF, van Houwelingen HC: Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: Correction for ascertainment. J Med Genet 42:491-496, 2005
    • (2005) J Med Genet , vol.42 , pp. 491-496
    • Quehenberger, F.1    Vasen, H.F.2    Van Houwelingen, H.C.3
  • 21
    • 33645826906 scopus 로고    scopus 로고
    • Cancer risks for mismatch repair gene mutation carriers: A population-based early onset case-family study
    • Jenkins MA, Baglietto L, Dowty JG, et al: Cancer risks for mismatch repair gene mutation carriers: A population-based early onset case-family study. Clin Gastroenterol Hepatol 4:489-498, 2006
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 489-498
    • Jenkins, M.A.1    Baglietto, L.2    Dowty, J.G.3
  • 22
    • 70350090521 scopus 로고    scopus 로고
    • Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome
    • Stoffel E, Mukherjee B, Raymond VM, et al: Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome. Gastroenterology 137:1621-1627, 2009
    • (2009) Gastroenterology , vol.137 , pp. 1621-1627
    • Stoffel, E.1    Mukherjee, B.2    Raymond, V.M.3
  • 23
    • 0032941343 scopus 로고    scopus 로고
    • Cancer risk in mutation carriers of DNA-mismatch-repair genes
    • Aarnio M, Sankila R, Pukkala E, et al: Cancer risk in mutation carriers of DNA-mismatch-repair genes. Int J Cancer 81:214-218, 1999
    • (1999) Int J Cancer , vol.81 , pp. 214-218
    • Aarnio, M.1    Sankila, R.2    Pukkala, E.3
  • 24
    • 59849108362 scopus 로고    scopus 로고
    • Recommendations from the EGAPP Working Group: Genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives
    • Recommendations from the EGAPP Working Group: Genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives. Genet Med 11:35-41, 2009
    • (2009) Genet Med , vol.11 , pp. 35-41
  • 25
    • 59849129653 scopus 로고    scopus 로고
    • EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome
    • Palomaki GE, McClain MR, Melillo S, et al: EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome. Genet Med 11:42-65, 2009
    • (2009) Genet Med , vol.11 , pp. 42-65
    • Palomaki, G.E.1    McClain, M.R.2    Melillo, S.3
  • 26
    • 84904701595 scopus 로고    scopus 로고
    • Guidelines on genetic evaluation and management of Lynch syndrome: A consensus statement by the US multi-society task force on colorectal cancer
    • Giardiello FM, Allen JI, Axilbund JE, et al: Guidelines on genetic evaluation and management of Lynch syndrome: A consensus statement by the US multi-society task force on colorectal cancer. Gastroenterology 147:502-526, 2014
    • (2014) Gastroenterology , vol.147 , pp. 502-526
    • Giardiello, F.M.1    Allen, J.I.2    Axilbund, J.E.3
  • 27
    • 84878234117 scopus 로고    scopus 로고
    • Risk of metachronous colon cancer following surgery for rectal cancer in mismatch repair gene mutation carriers
    • Win AK, Parry S, Parry B, et al: Risk of metachronous colon cancer following surgery for rectal cancer in mismatch repair gene mutation carriers. Ann Surg Oncol 20:1829-1836, 2013
    • (2013) Ann Surg Oncol , vol.20 , pp. 1829-1836
    • Win, A.K.1    Parry, S.2    Parry, B.3
  • 28
    • 0034011564 scopus 로고    scopus 로고
    • Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer
    • Järvinen HJ, Aarnio M, Mustonen H, et al: Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer. Gastroenterology 118:829-834, 2000
    • (2000) Gastroenterology , vol.118 , pp. 829-834
    • Järvinen, H.J.1    Aarnio, M.2    Mustonen, H.3
  • 29
    • 34848873408 scopus 로고    scopus 로고
    • Development of colorectal tumors in colonoscopic surveillance in Lynch syndrome
    • Mecklin JP, Aarnio M, Läärä E, et al: Development of colorectal tumors in colonoscopic surveillance in Lynch syndrome. Gastroenterology 133:1093-1098, 2007
    • (2007) Gastroenterology , vol.133 , pp. 1093-1098
    • Mecklin, J.P.1    Aarnio, M.2    Läärä, E.3
  • 30
    • 77952687174 scopus 로고    scopus 로고
    • One to 2-year surveillance intervals reduce risk of colorectal cancer in families with Lynch syndrome
    • Vasen HF, Abdirahman M, Brohet R, et al: One to 2-year surveillance intervals reduce risk of colorectal cancer in families with Lynch syndrome. Gastroenterology 138:2300-2306, 2010
    • (2010) Gastroenterology , vol.138 , pp. 2300-2306
    • Vasen, H.F.1    Abdirahman, M.2    Brohet, R.3
  • 31
    • 30944457531 scopus 로고    scopus 로고
    • Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome
    • Schmeler KM, Lynch HT, Chen LM, et al: Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome. N Engl J Med 354:261-269, 2006
    • (2006) N Engl J Med , vol.354 , pp. 261-269
    • Schmeler, K.M.1    Lynch, H.T.2    Chen, L.M.3
  • 32
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 61:759-767, 1990
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 33
    • 84864506477 scopus 로고    scopus 로고
    • Prevalence and phenotypes of APC and MUTYH mutations in patients with multiple colorectal adenomas
    • Grover S, Kastrinos F, Steyerberg EW, et al: Prevalence and phenotypes of APC and MUTYH mutations in patients with multiple colorectal adenomas. JAMA 308:485-492, 2012
    • (2012) JAMA , vol.308 , pp. 485-492
    • Grover, S.1    Kastrinos, F.2    Steyerberg, E.W.3
  • 35
    • 84920943765 scopus 로고    scopus 로고
    • Hereditary colorectal cancer syndromes: American Society of Clinical Oncology clinical practice guideline endorsement of the familial risk-colorectal cancer-European Society for Medical Oncology clinical practice guidelines
    • Stoffel EM, Mangu PB, Gruber SB, et al: Hereditary colorectal cancer syndromes: American Society of Clinical Oncology clinical practice guideline endorsement of the familial risk-colorectal cancer-European Society for Medical Oncology clinical practice guidelines. J Clin Oncol 33:209-217, 2015
    • (2015) J Clin Oncol , vol.33 , pp. 209-217
    • Stoffel, E.M.1    Mangu, P.B.2    Gruber, S.B.3
  • 36
    • 33947280508 scopus 로고    scopus 로고
    • Identification of MYH mutation carriers in colorectal cancer: A multicenter, case-control, population-based study
    • Balaguer F, Castellví-Bel S, Castells A, et al: Identification of MYH mutation carriers in colorectal cancer: A multicenter, case-control, population-based study. Clin Gastroenterol Hepatol 5:379-387, 2007
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 379-387
    • Balaguer, F.1    Castellví-Bel, S.2    Castells, A.3
  • 38
    • 77953230425 scopus 로고    scopus 로고
    • High cancer risk in Peutz-Jeghers syndrome: A systematic review and surveillance recommendations
    • author reply 65
    • van Lier MG, Wagner A, Mathus-Vliegen EM, et al: High cancer risk in Peutz-Jeghers syndrome: A systematic review and surveillance recommendations. Am J Gastroenterol 105:1258-1264, 2010; author reply 65
    • (2010) Am J Gastroenterol , vol.105 , pp. 1258-1264
    • Van Lier, M.G.1    Wagner, A.2    Mathus-Vliegen, E.M.3
  • 39
    • 84920053931 scopus 로고    scopus 로고
    • Cowden syndrome: Recognizing and managing a not-so-rare hereditary cancer syndrome
    • Mester J, Eng C: Cowden syndrome: Recognizing and managing a not-so-rare hereditary cancer syndrome. J Surg Oncol 111:125-130, 2015
    • (2015) J Surg Oncol , vol.111 , pp. 125-130
    • Mester, J.1    Eng, C.2
  • 40
    • 78649707989 scopus 로고    scopus 로고
    • Frequent gastrointestinal polyps and colorectal adenocarcinomas in a prospective series of PTEN mutation carriers
    • Heald B, Mester J, Rybicki L, et al: Frequent gastrointestinal polyps and colorectal adenocarcinomas in a prospective series of PTEN mutation carriers. Gastroenterology 139:1927-1933, 2010
    • (2010) Gastroenterology , vol.139 , pp. 1927-1933
    • Heald, B.1    Mester, J.2    Rybicki, L.3
  • 41
    • 20244386256 scopus 로고    scopus 로고
    • Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: Familial colorectal cancer type X
    • Lindor NM, Rabe K, Petersen GM, et al: Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: Familial colorectal cancer type X. JAMA 293:1979-1985, 2005
    • (2005) JAMA , vol.293 , pp. 1979-1985
    • Lindor, N.M.1    Rabe, K.2    Petersen, G.M.3
  • 42
    • 84907270779 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of gastric adenocarcinoma
    • Cancer Genome Atlas Research Network: Comprehensive molecular characterization of gastric adenocarcinoma. Nature 513:202-209, 2014
    • (2014) Nature , vol.513 , pp. 202-209
    • Cancer Genome Atlas Research Network1
  • 43
    • 84864607654 scopus 로고    scopus 로고
    • Genetic testing by cancer site: Stomach
    • Chun N, Ford JM: Genetic testing by cancer site: Stomach. Cancer J 18:355-363, 2012
    • (2012) Cancer J , vol.18 , pp. 355-363
    • Chun, N.1    Ford, J.M.2
  • 44
    • 0037130889 scopus 로고    scopus 로고
    • Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program
    • Brose MS, Rebbeck TR, Calzone KA, et al: Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program. J Natl Cancer Inst 94:1365-1372, 2002
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1365-1372
    • Brose, M.S.1    Rebbeck, T.R.2    Calzone, K.A.3
  • 45
    • 79960845375 scopus 로고    scopus 로고
    • Gastric cancer in individuals with Li-Fraumeni syndrome
    • Masciari S, Dewanwala A, Stoffel EM, et al: Gastric cancer in individuals with Li-Fraumeni syndrome. Genet Med 13:651-657, 2011
    • (2011) Genet Med , vol.13 , pp. 651-657
    • Masciari, S.1    Dewanwala, A.2    Stoffel, E.M.3
  • 46
    • 77956110372 scopus 로고    scopus 로고
    • Hereditary diffuse gastric cancer: Updated consensus guidelines for clinical management and directions for future research
    • Fitzgerald RC, Hardwick R, Huntsman D, et al: Hereditary diffuse gastric cancer: Updated consensus guidelines for clinical management and directions for future research. J Med Genet 47:436-444, 2010
    • (2010) J Med Genet , vol.47 , pp. 436-444
    • Fitzgerald, R.C.1    Hardwick, R.2    Huntsman, D.3
  • 47
    • 84903128887 scopus 로고    scopus 로고
    • Prospective cohort study assessing outcomes of patients from families fulfilling criteria for hereditary diffuse gastric cancer undergoing endoscopic surveillance
    • Lim YC, di Pietro M, O'Donovan M, et al: Prospective cohort study assessing outcomes of patients from families fulfilling criteria for hereditary diffuse gastric cancer undergoing endoscopic surveillance. Gastrointest Endosc 80:78-87, 2014
    • (2014) Gastrointest Endosc , vol.80 , pp. 78-87
    • Lim, Y.C.1    Di Pietro, M.2    O'Donovan, M.3
  • 48
    • 84869091997 scopus 로고    scopus 로고
    • Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
    • Biankin AV, Waddell N, Kassahn KS, et al: Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 491:399-405, 2012
    • (2012) Nature , vol.491 , pp. 399-405
    • Biankin, A.V.1    Waddell, N.2    Kassahn, K.S.3
  • 49
    • 84930186085 scopus 로고    scopus 로고
    • BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: A PACGENE study
    • epub ahead of print on November 20
    • Zhen DB, Rabe KG, Gallinger S, et al: BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: A PACGENE study. Genet Med [epub ahead of print on November 20, 2014]
    • (2014) Genet Med
    • Zhen, D.B.1    Rabe, K.G.2    Gallinger, S.3
  • 50
    • 84923917285 scopus 로고    scopus 로고
    • Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer
    • Grant RC, Selander I, Connor AA, et al: Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer. Gastroenterology 148:556-564, 2015
    • (2015) Gastroenterology , vol.148 , pp. 556-564
    • Grant, R.C.1    Selander, I.2    Connor, A.A.3
  • 51
    • 70350733425 scopus 로고    scopus 로고
    • Risk of pancreatic cancer in families with Lynch syndrome
    • Kastrinos F, Mukherjee B, Tayob N, et al: Risk of pancreatic cancer in families with Lynch syndrome. JAMA 302:1790-1795, 2009
    • (2009) JAMA , vol.302 , pp. 1790-1795
    • Kastrinos, F.1    Mukherjee, B.2    Tayob, N.3
  • 52
    • 84938423709 scopus 로고    scopus 로고
    • Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer
    • Wolpin BM, Rizzato C, Kraft P, et al: Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. Nat Genet 46:994-1000, 2014
    • (2014) Nat Genet , vol.46 , pp. 994-1000
    • Wolpin, B.M.1    Rizzato, C.2    Kraft, P.3
  • 53
    • 76149107145 scopus 로고    scopus 로고
    • Inhibition of poly(ADP)-ribose polymerase as a therapeutic strategy for breast cancer
    • Comen EA, Robson M: Inhibition of poly(ADP)-ribose polymerase as a therapeutic strategy for breast cancer. Oncology (Williston Park) 24:55-62, 2010
    • (2010) Oncology (Williston Park) , vol.24 , pp. 55-62
    • Comen, E.A.1    Robson, M.2
  • 54
    • 84873412474 scopus 로고    scopus 로고
    • International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer
    • Canto MI, Harinck F, Hruban RH, et al: International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer. Gut 62:339-347, 2013
    • (2013) Gut , vol.62 , pp. 339-347
    • Canto, M.I.1    Harinck, F.2    Hruban, R.H.3
  • 55
    • 84904750123 scopus 로고    scopus 로고
    • Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment
    • Kurian AW, Hare EE, Mills MA, et al: Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment. J Clin Oncol 32:2001-2009, 2014
    • (2014) J Clin Oncol , vol.32 , pp. 2001-2009
    • Kurian, A.W.1    Hare, E.E.2    Mills, M.A.3
  • 56
    • 81055126264 scopus 로고    scopus 로고
    • Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
    • Walsh T, Casadei S, Lee MK, et al: Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. Proc Natl Acad Sci U S A 108:18032-18037, 2011
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 18032-18037
    • Walsh, T.1    Casadei, S.2    Lee, M.K.3
  • 57
    • 84876071726 scopus 로고    scopus 로고
    • Multiplex genetic testing for cancer susceptibility: Out on the high wire without a net?
    • Domchek SM, Bradbury A, Garber JE, et al: Multiplex genetic testing for cancer susceptibility: Out on the high wire without a net? J Clin Oncol 31:1267-1270, 2013
    • (2013) J Clin Oncol , vol.31 , pp. 1267-1270
    • Domchek, S.M.1    Bradbury, A.2    Garber, J.E.3
  • 58
    • 77649208372 scopus 로고    scopus 로고
    • American Society of Clinical Oncology policy statement update: Genetic and genomic testing for cancer susceptibility
    • Robson ME, Storm CD, Weitzel J, et al: American Society of Clinical Oncology policy statement update: Genetic and genomic testing for cancer susceptibility. J Clin Oncol 28:893-901, 2010
    • (2010) J Clin Oncol , vol.28 , pp. 893-901
    • Robson, M.E.1    Storm, C.D.2    Weitzel, J.3
  • 59
    • 70349956433 scopus 로고    scopus 로고
    • Finding the missing heritability of complex diseases
    • Manolio TA, Collins FS, Cox NJ, et al: Finding the missing heritability of complex diseases. Nature 461:747-753, 2009
    • (2009) Nature , vol.461 , pp. 747-753
    • Manolio, T.A.1    Collins, F.S.2    Cox, N.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.