Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation

British Journal of Pharmacology

Volumn 172, Issue 15, 2015, Pages 3748-3763

  Ailenberg, M ^a,b,c   Di Ciano Oliveira, C ^a,b,c   Szaszi, K ^a,b,c   Dan, Q ^a,b,c   Rozycki, M ^a,b,c   Kapus, A ^a,b,c   Rotstein, O D ^a,b,c  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; DYNASORE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOCHONDRIAL ANTIVIRAL SIGNALLING PROTEIN; MITOCHONDRIAL PROTEIN; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; HYDRAZONE DERIVATIVE; N'-(3,4-DIHYDROXYBENZYLIDENE)-3-HYDROXY-2-NAPHTHAHYDRAZIDE; RAC PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TOLL LIKE RECEPTOR 4; VISA PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENDOCYTOSIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; SIGNAL TRANSDUCTION; AGONISTS; ANIMAL; CELL LINE; DRUG EFFECTS; METABOLISM; MOUSE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL LINE; ENDOCYTOSIS; HUMANS; HYDRAZONES; INTERFERON-BETA; MICE; NF-KAPPA B; RAC GTP-BINDING PROTEINS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84937003284     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13162     Document Type: Article

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