Increasing avermectin production in Streptomyces avermitilis by manipulating the expression of a novel TetR-family regulator and its target gene product

Applied and Environmental Microbiology

Volumn 81, Issue 15, 2015, Pages 5157-5173

  Liu, Wenshuai ^a   Zhang, Qinling ^a   Guo, Jia ^a,b   Chen, Zhi ^a   Li, Jilun ^a   Wen, Ying ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b JIANGNAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOCHEMISTRY; FEEDBACK; GENE EXPRESSION; GENES; TRANSCRIPTION;

EFFICIENT STRATEGY; FEEDBACK REGULATION; GEL SHIFT ASSAYS; INDUSTRIAL STRAIN; MAJOR FACILITATOR SUPERFAMILY; REGULATORY MECHANISM; STREPTOMYCES AVERMITILIS; TRANSCRIPTIONAL REGULATOR;

GENE EXPRESSION REGULATION;

BACTERIUM; GENE EXPRESSION; INDUSTRIAL PRODUCTION; INSECTICIDE; LIGAND; MORPHOLOGY; PROTEIN;

STREPTOMYCES AVERMITILIS;

ANTHELMINTIC AGENT; AVERMECTIN; BACTERIAL DNA; IVERMECTIN; PROTEIN BINDING; TRANSCRIPTION FACTOR;

ANALOGS AND DERIVATIVES; CALIFORNIA ENCEPHALITIS VIRUS; CYTOLOGY; GEL MOBILITY SHIFT ASSAY; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLIC ENGINEERING; METABOLISM; STREPTOMYCES;

ANTHELMINTICS; DNA, BACTERIAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENCEPHALITIS VIRUS, CALIFORNIA; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION, BACTERIAL; IVERMECTIN; METABOLIC ENGINEERING; PROTEIN BINDING; STREPTOMYCES; TRANSCRIPTION FACTORS;

EID: 84936972379     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.00868-15     Document Type: Article

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