The pathway-specific regulator AveR from Streptomyces avermitilis positively regulates avermectin production while it negatively affects oligomycin biosynthesis

Molecular Genetics and Genomics

Volumn 283, Issue 2, 2010, Pages 123-133

  Guo, Jia ^a   Zhao, Jinlei ^a   Li, Lili ^a   Chen, Zhi ^a   Wen, Ying ^a   Li, Jilun ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

AveR gene; Avermectin biosynthesis; Oligomycin biosynthesis; Pathway specific activator; Streptomyces avermitilis

Indexed keywords

AVERMECTIN; OLIGOMYCIN; PROTEIN AVER; REGULATOR PROTEIN; UNCLASSIFIED DRUG; DRUG DERIVATIVE; HELIX LOOP HELIX PROTEIN; IVERMECTIN; LUXR AUTOINDUCER BINDING PROTEINS; REPRESSOR PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; BIOSYNTHESIS; CHROMATIN IMMUNOPRECIPITATION; DNA BINDING; FERMENTATION; GENE DELETION; GENE EXPRESSION; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOMYCES; STREPTOMYCES AVERMITILIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MULTIGENE FAMILY; PROMOTER REGION;

PROTEIDAE; STREPTOMYCES AVERMITILIS;

CHROMATIN IMMUNOPRECIPITATION; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; HELIX-TURN-HELIX MOTIFS; IVERMECTIN; MULTIGENE FAMILY; OLIGOMYCINS; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; STREPTOMYCES; TRANS-ACTIVATORS;

EID: 75649122638     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-009-0502-2     Document Type: Article

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