The legionella kinase legk2 targets the arp2/3 complex to inhibit actin nucleation on phagosomes and allow bacterial evasion of the late endocytic pathway

mBio

Volumn 6, Issue 3, 2015, Pages 1-14

  Michard, Céline ^a,b,c,d   Sperandio, Daniel ^a,b,c,d   Baïlo, Nathalie ^a,b,c,d   Pizarro Cerdá, Javier ^b,e,f   LeClaire, Lawrence ^g   Chadeau Argaud, Elise ^a,b,c,d   Pombo Grégoire, Isabel ^a,b,c,d   Hervet, Eva ^a,b,c,d   Vianney, Anne ^a,b,c,d   Gilbert, Christophe ^a,b,c,d   Faure, Mathias ^a,b,c,d   Cossart, Pascale ^b,e,f   Doublet, Patricia ^a,b,c,d  

^a CENTRE INTERNATIONAL DE RECHERCHE EN INFECTIOLOGIE   (France)

^b INSERM   (France)

^c UNIVERSITÉ DE LYON   (France)

^d CNRS   (France)

^e INSTITUT PASTEUR   (France)

^f USC 2020   (France)

^g UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN RELATED PROTEIN 2-3 COMPLEX; PROTEIN KINASE; PROTEIN LEGK2; UNCLASSIFIED DRUG; BACTERIAL PROTEIN;

ACTIN FILAMENT; ACTIN NUCLEATION; ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; BACTERIAL EVASION; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DICTYOSTELIUM DISCOIDEUM; ENDOCYTOSIS; ENZYME ANALYSIS; GENE INACTIVATION; HEK293 CELL LINE; HELA CELL LINE; HOST CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LEGIONELLA PNEUMOPHILA; LEGIONNAIRE DISEASE; NONHUMAN; PHAGOSOME; PLASMID; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; CELL VACUOLE; ENDOSOME; ENZYMOLOGY; GENETICS; LYSOSOME; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHOSPHORYLATION; PROTEIN TRANSPORT;

BACTERIA (MICROORGANISMS); LEGIONELLA; LEGIONELLA PNEUMOPHILA; LISTERIA MONOCYTOGENES;

ACTIN-RELATED PROTEIN 2-3 COMPLEX; ACTINS; BACTERIAL PROTEINS; ENDOSOMES; LEGIONELLA PNEUMOPHILA; LYSOSOMES; PHAGOSOMES; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN TRANSPORT; VACUOLES;

EID: 84936941703     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00354-15     Document Type: Article

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