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Volumn 254, Issue 5, 1997, Pages 562-570

Analyses of Saccharomyces cerevisiae Cdc7 kinase point mutants: Dominant-negative inhibition of DNA replication on overexpression of kinase-negative Cdc7 proteins

Author keywords

Cdc7 kinase; DNA replication; Dominant negative mutant; G1 S transition; Saccharomyces cerevisiae

Indexed keywords

CYCLIN DEPENDENT KINASE; FUNGAL DNA; MUTANT PROTEIN;

EID: 0030925249     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050452     Document Type: Article
Times cited : (17)

References (42)
  • 2
    • 0025966676 scopus 로고
    • A role for CDC7 in repression of transcription at the silent mating-type locus HMR in Saccharomyces cerevisiae
    • Axelrod A, Rine J (1991) A role for CDC7 in repression of transcription at the silent mating-type locus HMR in Saccharomyces cerevisiae. Mol Cell Biol 11:1080-1091
    • (1991) Mol Cell Biol , vol.11 , pp. 1080-1091
    • Axelrod, A.1    Rine, J.2
  • 3
    • 0024203010 scopus 로고
    • Characterization of the CDC7 gene product of Saccharomyces cerevisiae as a protein kinase needed for the initiation of mitotic DNA synthesis
    • Bahman M, Buck V, White A, Rosamond J (1988) Characterization of the CDC7 gene product of Saccharomyces cerevisiae as a protein kinase needed for the initiation of mitotic DNA synthesis. Biochim Biophys Acta 951:335-343
    • (1988) Biochim Biophys Acta , vol.951 , pp. 335-343
    • Bahman, M.1    Buck, V.2    White, A.3    Rosamond, J.4
  • 4
    • 0026607331 scopus 로고
    • ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex
    • Bell SP, Stillman B (1992) ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex. Nature 357:128-134
    • (1992) Nature , vol.357 , pp. 128-134
    • Bell, S.P.1    Stillman, B.2
  • 5
    • 0025835604 scopus 로고
    • CDC7 protein kinase activity is required for mitosis and meiosis in Saccharomyces cerevisiae
    • Buck V, White A, Rosamond J (1991) CDC7 protein kinase activity is required for mitosis and meiosis in Saccharomyces cerevisiae. Mol Gen Genet 227:452-457
    • (1991) Mol Gen Genet , vol.227 , pp. 452-457
    • Buck, V.1    White, A.2    Rosamond, J.3
  • 6
    • 0024545513 scopus 로고
    • The yeast gene, DBF4, essential for entry into S phase is cell cycle regulated
    • Chapman JW, Johnston LH (1989) The yeast gene, DBF4, essential for entry into S phase is cell cycle regulated. Exp Cell Res 180:419-428
    • (1989) Exp Cell Res , vol.180 , pp. 419-428
    • Chapman, J.W.1    Johnston, L.H.2
  • 7
    • 0027978640 scopus 로고
    • Interaction of Dbf4, the Cdc7 protein kinase regulatory subunit, with yeast replication origins in vivo
    • Dowell SJ, Romanowski P, Diffley JFX (1994) Interaction of Dbf4, the Cdc7 protein kinase regulatory subunit, with yeast replication origins in vivo. Science 265:1243-1246
    • (1994) Science , vol.265 , pp. 1243-1246
    • Dowell, S.J.1    Romanowski, P.2    Diffley, J.F.X.3
  • 9
    • 0024266139 scopus 로고
    • New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
    • Gietz RD, Sugino A (1988) New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74:527-534
    • (1988) Gene , vol.74 , pp. 527-534
    • Gietz, R.D.1    Sugino, A.2
  • 10
    • 0026070261 scopus 로고
    • Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function
    • Gould KL, Moreno S, Owen DJ, Sazar S, Nurse P (1991) Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function. EMBO J 10:3297-3309
    • (1991) EMBO J , vol.10 , pp. 3297-3309
    • Gould, K.L.1    Moreno, S.2    Owen, D.J.3    Sazar, S.4    Nurse, P.5
  • 11
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
    • Hanks SK, Quinn AM, Hunter T (1988) The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 241:42-52
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 12
    • 0015796354 scopus 로고
    • Three additional genes required for deoxyribonucleic acid synthesis in Saccharomyces cerevisiae
    • Hartwell LH (1973) Three additional genes required for deoxyribonucleic acid synthesis in Saccharomyces cerevisiae. J Bacteriol 115:966-974
    • (1973) J Bacteriol , vol.115 , pp. 966-974
    • Hartwell, L.H.1
  • 13
    • 0015847513 scopus 로고
    • Genetic control of the cell cycle division in yeast. V. Genetic analysis of cdc mutants
    • Hartwell LH, Mortimer RK, Culotti J, Culotti M (1973) Genetic control of the cell cycle division in yeast. V. Genetic analysis of cdc mutants. Genetics 74:267-286
    • (1973) Genetics , vol.74 , pp. 267-286
    • Hartwell, L.H.1    Mortimer, R.K.2    Culotti, J.3    Culotti, M.4
  • 14
    • 0016392796 scopus 로고
    • Sequential gene function in the initiation of Saccharomyces cerevisiae DNA synthesis
    • Hereford LM, Hartwell LH (1974) Sequential gene function in the initiation of Saccharomyces cerevisiae DNA synthesis, J Mol Biol 84:445-461
    • (1974) J Mol Biol , vol.84 , pp. 445-461
    • Hereford, L.M.1    Hartwell, L.H.2
  • 15
    • 0025030685 scopus 로고
    • DNA metabolism gene CDC7 from yeast encodes a serine (threonine) protein kinase
    • Hollingsworth RE, Sclafani RA (1990) DNA metabolism gene CDC7 from yeast encodes a serine (threonine) protein kinase. Proc Natl Acad Sci USA 87:6272-6276
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6272-6276
    • Hollingsworth, R.E.1    Sclafani, R.A.2
  • 16
    • 0027192941 scopus 로고
    • Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 Protein
    • Jackson AL, Pahl PMB, Harrison K, Rosamond J, Sclafani RA (1993) Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 Protein. Mol Cell Biol 13:2899-2908
    • (1993) Mol Cell Biol , vol.13 , pp. 2899-2908
    • Jackson, A.L.1    Pahl, P.M.B.2    Harrison, K.3    Rosamond, J.4    Sclafani, R.A.5
  • 17
    • 0020429773 scopus 로고
    • A further two mutants defective in initiation of the S phase in the yeast Saccharomyces cerevisiae
    • Johnslon LH, Thomas AP (1982) A further two mutants defective in initiation of the S phase in the yeast Saccharomyces cerevisiae. Mol Gen Genet 186:445-448
    • (1982) Mol Gen Genet , vol.186 , pp. 445-448
    • Johnslon, L.H.1    Thomas, A.P.2
  • 18
    • 0022477077 scopus 로고
    • cdc7 alleles and the control of induced mutagenesis in yeast
    • Kilbey BJ (1986) cdc7 alleles and the control of induced mutagenesis in yeast. Mutagenesis 1:29-31
    • (1986) Mutagenesis , vol.1 , pp. 29-31
    • Kilbey, B.J.1
  • 19
    • 0027173110 scopus 로고
    • A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dhf4 encodes a protein kinase and is identified as CDC5
    • Kitada K, Johnson AL, Sugino A (1993) A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dhf4 encodes a protein kinase and is identified as CDC5. Mol Cell Biol 13:4445-4457
    • (1993) Mol Cell Biol , vol.13 , pp. 4445-4457
    • Kitada, K.1    Johnson, A.L.2    Sugino, A.3
  • 20
    • 0026635563 scopus 로고
    • Temperature-sensitive cdc7 mutations of Saccharomyces cerevisiae are suppressed by the DBF4 gene, which is required for the G1/S cell cycle transition
    • Kitada K, Johnston LH, Sugino T, Sugino A (1992) Temperature-sensitive cdc7 mutations of Saccharomyces cerevisiae are suppressed by the DBF4 gene, which is required for the G1/S cell cycle transition. Genetics 131:21-29
    • (1992) Genetics , vol.131 , pp. 21-29
    • Kitada, K.1    Johnston, L.H.2    Sugino, T.3    Sugino, A.4
  • 21
    • 0026326821 scopus 로고
    • Structure of a peptide inhibitor bound to the catalytic subunit of cyclic Adenosine Monophosphate-dependent protein kinase
    • Knighton DR, Zheng J, Eyck LFT, Xuong N, Taylor SS, Sowadski JM (1991) Structure of a peptide inhibitor bound to the catalytic subunit of cyclic Adenosine Monophosphate-dependent protein kinase. Science 253:414-420
    • (1991) Science , vol.253 , pp. 414-420
    • Knighton, D.R.1    Zheng, J.2    Eyck, L.F.T.3    Xuong, N.4    Taylor, S.S.5    Sowadski, J.M.6
  • 22
    • 2642699794 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • Kunkel TA (1985) Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci USA 82:488-492
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 488-492
    • Kunkel, T.A.1
  • 23
    • 0023613953 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • Kunkel TA, Roberts JD, Zakour RA (1987) Rapid and efficient site-specific mutagenesis without phenotypic selection. Meth Enzymol 154:367-382
    • (1987) Meth Enzymol , vol.154 , pp. 367-382
    • Kunkel, T.A.1    Roberts, J.D.2    Zakour, R.A.3
  • 24
    • 0028979307 scopus 로고
    • hsk 1' , a Schizosaccharomyces pombe gene related to Saccharomyces cerevisiae CDC7, is required for chromosomal replication
    • Masai H, Miyake T, Arai K (1995) hsk 1' , a Schizosaccharomyces pombe gene related to Saccharomyces cerevisiae CDC7, is required for chromosomal replication. EMBO J 14:3094-3104
    • (1995) EMBO J , vol.14 , pp. 3094-3104
    • Masai, H.1    Miyake, T.2    Arai, K.3
  • 25
    • 0021870935 scopus 로고
    • Cloning of the CDC7 gene of Saccharomyces cerevisiae in association with centromeric DNA
    • Meddle CC, Kumar P, Ham J, Hughes DA, Johnston IR (1984) Cloning of the CDC7 gene of Saccharomyces cerevisiae in association with centromeric DNA. Gene 34:179-186
    • (1984) Gene , vol.34 , pp. 179-186
    • Meddle, C.C.1    Kumar, P.2    Ham, J.3    Hughes, D.A.4    Johnston, I.R.5
  • 26
    • 0023793683 scopus 로고
    • Dominant negative protein kinase mutations that confer a G1 arrest phenotype
    • Mendenhall MD, Richardson HE, Reed S (1988) Dominant negative protein kinase mutations that confer a G1 arrest phenotype. Proc Natl Acad Sci USA 85:4426-4430
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4426-4430
    • Mendenhall, M.D.1    Richardson, H.E.2    Reed, S.3
  • 27
    • 0027183207 scopus 로고
    • Suppression of oncogenic Ras by mutant neurofibromatosis type I genes with single amino acid substitutions
    • Nakafuku M, Nagamine M, Ohtoshi A, Tanaka K, Toh-e A, Kaziro Y (1993) Suppression of oncogenic Ras by mutant neurofibromatosis type I genes with single amino acid substitutions. Proc Natl Acad Sci USA 90:6706-6710
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6706-6710
    • Nakafuku, M.1    Nagamine, M.2    Ohtoshi, A.3    Tanaka, K.4    Toh-e, A.5    Kaziro, Y.6
  • 28
    • 0025946804 scopus 로고
    • Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation
    • Ninomiyu-Tsuji J, Nomoto S, Yasuda H, Reed SI. Matumoto K (1991) Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation. Proc Natl Acad Sci USA 88:9006-9010
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 9006-9010
    • Ninomiyu-Tsuji, J.1    Nomoto, S.2    Yasuda, H.3    Reed, S.I.4    Matumoto, K.5
  • 29
    • 0020411589 scopus 로고
    • cdc7-I, a temperature-sensitive cell-cycle mutant which interferes with induced mutagenesis in Saccharomyces cerevisiae
    • Njagi GDE, Kilbey BJ (1982) cdc7-I, a temperature-sensitive cell-cycle mutant which interferes with induced mutagenesis in Saccharomyces cerevisiae. Mol Gen Genet 186:478-481
    • (1982) Mol Gen Genet , vol.186 , pp. 478-481
    • Njagi, G.D.E.1    Kilbey, B.J.2
  • 30
    • 0030257038 scopus 로고    scopus 로고
    • Genetic interactions between CDC7 and CDC28: Growth inhibition of cdc28-IN by Cdc7 point mutants
    • Ohtoshi A, Arai K, Masai H (1996) Genetic interactions between CDC7 and CDC28: growth inhibition of cdc28-IN by Cdc7 point mutants. Genes to Cells 1:895-904
    • (1996) Genes to Cells , vol.1 , pp. 895-904
    • Ohtoshi, A.1    Arai, K.2    Masai, H.3
  • 31
    • 0022602028 scopus 로고
    • Molecular characterization of cell cycle gene CDC7 from Saccharomyces cerevisiae
    • Patterson M, Sclafani RA, Fangman WL, Rosamond J (1986) Molecular characterization of cell cycle gene CDC7 from Saccharomyces cerevisiae. Mol Cell Biol 6:1590-1598
    • (1986) Mol Cell Biol , vol.6 , pp. 1590-1598
    • Patterson, M.1    Sclafani, R.A.2    Fangman, W.L.3    Rosamond, J.4
  • 32
    • 0025291669 scopus 로고
    • Mitotic role for the Cdc28 protein kinase of Saccharomyces cerevisiae
    • Reed SI, Wittenberg C (1990) Mitotic role for the Cdc28 protein kinase of Saccharomyces cerevisiae. Proc Natl Acad Sci USA 87:5697-5701
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5697-5701
    • Reed, S.I.1    Wittenberg, C.2
  • 34
    • 0028322222 scopus 로고
    • Cdc7 protein kinase for DNA metabolism comes of age
    • Sclafani RA, Jackson AL (1994) Cdc7 protein kinase for DNA metabolism comes of age. Mol Microbiol 11:805-810
    • (1994) Mol Microbiol , vol.11 , pp. 805-810
    • Sclafani, R.A.1    Jackson, A.L.2
  • 35
    • 0023800224 scopus 로고
    • Differential regulation of the yeast CDC7 gene during mitosis and meiosis
    • Sclafani RA, Patterson M, Rosamond J, Fangman WL (1988) Differential regulation of the yeast CDC7 gene during mitosis and meiosis. Mol Cell Biol 8:293-300
    • (1988) Mol Cell Biol , vol.8 , pp. 293-300
    • Sclafani, R.A.1    Patterson, M.2    Rosamond, J.3    Fangman, W.L.4
  • 36
    • 0016200419 scopus 로고
    • Are mitotic functions required in meiosis?
    • Simchen G (1974) Are mitotic functions required in meiosis? Genetics 76:745-753
    • (1974) Genetics , vol.76 , pp. 745-753
    • Simchen, G.1
  • 37
    • 0027007963 scopus 로고
    • Role of phosphorylation in p34cdc2 activation: Identification of an activating kinase
    • Solomon MJ, Lee T, Kirschner MW (1992) Role of phosphorylation in p34cdc2 activation: identification of an activating kinase. Mol Biol Cell 3:13-27
    • (1992) Mol Biol Cell , vol.3 , pp. 13-27
    • Solomon, M.J.1    Lee, T.2    Kirschner, M.W.3
  • 39
    • 0025192609 scopus 로고
    • The dominant W42 spotting phenotype results from a missense mutation in the c-kit receptor kinase
    • Tan JC, Nocka K, Ray P, Traktman P, Besmer P (1990) The dominant W42 spotting phenotype results from a missense mutation in the c-kit receptor kinase. Science 247:209-212
    • (1990) Science , vol.247 , pp. 209-212
    • Tan, J.C.1    Nocka, K.2    Ray, P.3    Traktman, P.4    Besmer, P.5
  • 40
    • 0027919126 scopus 로고
    • Mutations on 170Glu, a substrate recognition residue in mouse cAMP-dependent protein kinase, generate enzymes with altered substrate affinity and biological functions
    • Tomoda T, Murata T, Arai K, Muramatsu M (1993) Mutations on 170Glu, a substrate recognition residue in mouse cAMP-dependent protein kinase, generate enzymes with altered substrate affinity and biological functions. Biochim Biophys Acta 1175:333-342
    • (1993) Biochim Biophys Acta , vol.1175 , pp. 333-342
    • Tomoda, T.1    Murata, T.2    Arai, K.3    Muramatsu, M.4
  • 41
    • 0025806760 scopus 로고
    • The CDC7 protein of Saccharomyces cerevisiae is a phosphoprotein that contains protein kinase activity
    • Yoon H, Campbell JL (1991) The CDC7 protein of Saccharomyces cerevisiae is a phosphoprotein that contains protein kinase activity. Proc Natl Acad Sci USA 88:3574-3578
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3574-3578
    • Yoon, H.1    Campbell, J.L.2
  • 42
    • 0027479493 scopus 로고
    • Regulation of Saccharomyces cerevisiae CDC7 function during the cell cycle
    • Yoon H, Loo S, Campbell JL (1993) Regulation of Saccharomyces cerevisiae CDC7 function during the cell cycle. Mol Biol Cell 4:195-208
    • (1993) Mol Biol Cell , vol.4 , pp. 195-208
    • Yoon, H.1    Loo, S.2    Campbell, J.L.3


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