Functional characterizations of IPS-1 in CIK cells: Potential roles in regulating IFN-I response dependent on IRF7 but not IRF3

Developmental and Comparative Immunology

Volumn 53, Issue 1, 2015, Pages 23-32

  Feng, Xiaoli ^a   Zhang, Yixuan ^a   Yang, Chunrong ^b   Liao, Lanjie ^c   Wang, Yaping ^c   Su, Jianguo ^a,b  

^a NORTHWEST A F UNIVERSITY   (China)

^b HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^c INSTITUTE OF HYDROBIOLOGY   (China)

Author keywords

Functional characteristics; Grass carp (Ctenopharyngodon idella); Grass carp reovirus; IPS 1

Indexed keywords

INTERFERON; INTERFERON BETA PROMOTER SIGNALING PROTEIN 1; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 1BETA; SIGNAL PEPTIDE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; UNCLASSIFIED DRUG; LIPOPOLYSACCHARIDE; MYXOVIRUS RESISTANCE PROTEIN; PEPTIDOGLYCAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CARD DOMAIN; CIIFN I GENE; CIIL 1B GENE; CIIRF3 GENE; CIIRF7 GENE; CIMX1 GENE; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE EXPRESSION REGULATION; GRASS CARP; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROLINE RICH PROTEIN DOMAIN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CARP; CELL CULTURE; FISH DISEASE; GENETICS; IMMUNOLOGY; PROTEIN TERTIARY STRUCTURE; REOVIRIDAE; VIROLOGY;

CTENOPHARYNGODON; CTENOPHARYNGODON IDELLA; GRASS CARP REOVIRUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARPS; CELLS, CULTURED; FISH DISEASES; INTERFERON REGULATORY FACTOR-3; INTERFERON REGULATORY FACTOR-7; INTERFERON TYPE I; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MYXOVIRUS RESISTANCE PROTEINS; PEPTIDOGLYCAN; PROTEIN STRUCTURE, TERTIARY; REOVIRIDAE; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS;

EID: 84936889313     PISSN: 0145305X     EISSN: 18790089     Source Type: Journal    
DOI: 10.1016/j.dci.2015.06.005     Document Type: Article

References (39)

1. Belgnaoui S.M., Paz S., Hiscott J. Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter. Curr. Opin. Immunol. 2011, 23:564-572.
2. Biacchesi S., LeBerre M., Lamoureux A., Louise Y., Lauret E., Boudinot P., Bremont M. Mitochondrial antiviral signaling protein plays a major role in induction of the fish innate immune response against RNA and DNA viruses. J.Virol. 2009, 83:7815-7827.
3. Biacchesi S., Merour E., Lamoureux A., Bernard J., Bremont M. Both STING and MAVS fish orthologs contribute to the induction of interferon mediated by RIG-I. PLoS One 2012, 7:e47737.
4. Bruns A.M., Horvath C.M. Antiviral RNA recognition and assembly by RLR family innate immune sensors. Cytokine Growth Factor Rev. 2014, 25:507-512.
5. Chen L., Li Q., Su J., Yang C., Li Y., Rao Y. Trunk kidney of grass carp (Ctenopharyngodon idella) mediates immune responses against GCRV and viral/bacterial PAMPs invivo and invitro. Fish Shellfish Immunol. 2013, 34:909-919.
6. Chen L., Su J., Yang C., Peng L., Wan Q., Wang L. Functional characterizations of RIG-I to GCRV and viral/bacterial PAMPs in grass carp Ctenopharyngodon idella. PLoS One 2012, 7:e42182.
7. Chen W.Q., Hu Y.W., Zou P.F., Ren S.S., Nie P., Chang M.X. MAVS splicing variants contribute to the induction of interferon and interferon-stimulated genes mediated by RIG-I-like receptors. Dev. Comp. Immunol. 2015, 49:19-30.
8. Chen X., Yang C., Su J., Rao Y., Gu T. LGP2 plays extensive roles in modulating innate immune responses in Ctenopharyngodon idella kidney (CIK) cells. Dev. Comp. Immunol. 2015, 49:138-148.
9. Chiang J.J., Davis M.E., Gack M.U. Regulation of RIG-I-like receptor signaling by host and viral proteins. Cytokine Growth Factor Rev. 2014, 25:491-505.
10. Feng X., Su J., Yang C., Yan N., Rao Y., Chen X. Molecular characterizations of grass carp (Ctenopharyngodon idella) TBK1 gene and its roles in regulating IFN-I pathway. Dev. Comp. Immunol. 2014, 45:278-290.
11. Honda K., Taniguchi T. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat. Rev. Immunol. 2006, 6:644-658.
12. Hou F., Sun L., Zheng H., Skaug B., Jiang Q.X., Chen Z.J. MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell 2011, 146:448-461.
13. Jacobs J.L., Coyne C.B. Mechanisms of MAVS regulation at the mitochondrial membrane. J.Mol. Biol. 2013, 425:5009-5019.
14. Kumar H., Kawai T., Kato H., Sato S., Takahashi K., Coban C., Yamamoto M., Uematsu S., Ishii K.J., Takeuchi O., Akira S. Essential role of IPS-1 in innate immune responses against RNA viruses. J.Exp. Med. 2006, 203:1795-1803.
15. Lad S.P., Yang G., Scott D.A., Chao T.H., Correia Jda S., de la Torre J.C., Li E. Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling. Mol. Immunol. 2008, 45:2277-2287.
16. Lauksund S., Svingerud T., Bergan V., Robertsen B. Atlantic salmon IPS-1 mediates induction of IFNa1 and activation of NF-kappaB and localizes to mitochondria. Dev. Comp. Immunol. 2009, 33:1196-1204.
17. Leung D.W., Basler C.F., Amarasinghe G.K. Molecular mechanisms of viral inhibitors of RIG-I-like receptors. Trends Microbiol. 2012, 20:139-146.
18. Loo Y.M., Gale M. Immune signaling by RIG-I-like receptors. Immunity 2011, 34:680-692.
19. Okazaki T., Higuchi M., Gotoh Y. Mitochondrial localization of the antiviral signaling adaptor IPS-1 is important for its induction of caspase activation. Genes Cells 2013, 18:493-501.
20. Paz S., Sun Q., Nakhaei P., Romieu-Mourez R., Goubau D., Julkunen I., Lin R., Hiscott J. Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway. Cell. Mol. Biol. (Noisy-le-grand) 2006, 52:17-28.
21. Poeck H., Ruland J. From virus to inflammation: mechanisms of RIG-I-induced IL-1beta production. Eur. J. Cell Biol. 2012, 91:59-64.
22. Qi B., Huang Y., Rowe D., Halliday G. VISA-a pass to innate immunity. Int. J. Biochem. Cell Biol. 2007, 39:287-291.
23. Rao Y., Su J. Insights into the antiviral immunity against grass carp (Ctenopharyngodon idella) reovirus (GCRV) in grass carp. J.Immunol. Res. 2015, 2015:670437.
24. Schlee M. Master sensors of pathogenic RNA - RIG-I like receptors. Immunobiology 2013, 218:1322-1335.
25. Sergerie Y., Rivest S., Boivin G. Tumor necrosis factor-alpha and interleukin-1 beta play a critical role in the resistance against lethal herpes simplex virus encephalitis. J.Infect. Dis. 2007, 196:853-860.
26. Seth R.B., Sun L., Ea C.K., Chen Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF3. Cell 2005, 122:669-682.
27. Simora R.M.C., Ohtani M., Hikima J.-I., Kondo H., Hirono I., Jung T.S., Aoki T. Molecular cloning and antiviral activity of IFN-β promoter stimulator-1 (IPS-1) gene in Japanese flounder, Paralichthys olivaceus. Fish Shellfish Immunol. 2010, 29:979-986.
28. Su J., Huang T., Yang C., Zhang R. Molecular cloning, characterization and expression analysis of interferon-beta promoter stimulator 1 (IPS-1) gene from grass carp Ctenopharyngodon idella. Fish Shellfish Immunol. 2011, 30:317-323.
29. Sun F., Zhang Y.B., Liu T.K., Shi J., Wang B., Gui J.F. Fish MITA serves as a mediator for distinct fish IFN gene activation dependent on IRF3 or IRF7. J.Immunol. 2011, 187:2531-2539.
30. Suthar M.S., Ma D.Y., Thomas S., Lund J.M., Zhang N., Daffis S., Rudensky A.Y., Bevan M.J., Clark E.A., Kaja M.K., Diamond M.S., Gale M. IPS-1 is essential for the control of West Nile virus infection and immunity. PLoS Pathog. 2010, 6:e1000757.
31. Takamatsu S., Onoguchi K., Onomoto K., Narita R., Takahasi K., Ishidate F., Fujiwara T.K., Yoneyama M., Kato H., Fujita T. Functional characterization of domains of IPS-1 using an inducible oligomerization system. PLoS One 2013, 8:e53578.
32. Takeuchi O., Akira S. MDA5/RIG-I and virus recognition. Curr. Opin. Immunol. 2008, 20:17-22.
33. Xiang Z., Qi L., Chen W., Dong C., Liu Z., Liu D., Huang M., Li W., Yang G., Weng S., He J. Characterization of a TnMAVS protein from Tetraodon nigroviridis. Dev. Comp. Immunol. 2011, 35:1103-1115.
34. Yang C., Peng L., Su J. Two HMGB1 genes from grass carp Ctenopharyngodon idella mediate immune responses to viral/bacterial PAMPs and GCRV challenge. Dev. Comp. Immunol. 2013, 39:133-146.
35. Yasukawa K., Oshiumi H., Takeda M., Ishihara N., Yanagi Y., Seya T., Kawabata S., Koshiba T. Mitofusin 2 inhibits mitochondrial antiviral signaling. Sci. Signal. 2009, 2:ra47.
36. Yoo J.S., Kato H., Fujita T. Sensing viral invasion by RIG-I like receptors. Curr. Opin. Microbiol. 2014, 20C:131-138.
37. Zhang J., Zhang Y.B., Wu M., Wang B., Chen C., Gui J.F. Fish MAVS is involved in RLR pathway-mediated IFN response. Fish Shellfish Immunol. 2014, 41:222-230.
38. Zhang Y.B., Gui J.F. Molecular regulation of interferon antiviral response in fish. Dev. Comp. Immunol. 2012, 38:193-202.
39. Zou J., Kawai T., Tsuchida T., Kozaki T., Tanaka H., Shin K.S., Kumar H., Akira S. Poly IC triggers a cathepsin D- and IPS-1-dependent pathway to enhance cytokine production and mediate dendritic cell necroptosis. Immunity 2013, 38:717-728.