Targeted next generation sequencing application in cardiac channelopathies: Analysis of a cohort of autopsy-negative sudden unexplained deaths

Forensic Science International

Volumn 254, Issue , 2015, Pages 5-11

  Farrugia, A ^a   Keyser, C ^a,b   Hollard, C ^a,b   Raul, J S ^a   Muller, J ^b,c   Ludes, B ^b,d  

^a INSTITUT DE MÉDECINE LÉGALE   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c Faculté de Médecine   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Cardiac channelopathies; Molecular autopsy; Next generation sequencing; Sudden cardiac death

Indexed keywords

PANTOTHENATE KINASE 2; RYANODINE RECEPTOR 2; SODIUM CHANNEL NAV1.5; ANK2 PROTEIN, HUMAN; ANKYRIN; CALSEQUESTRIN; CASQ2 PROTEIN, HUMAN; ERG1 POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG; RYANODINE RECEPTOR; SCN5A PROTEIN, HUMAN;

ADULT; ANK2 GENE; ARTICLE; AUTOPSY; CARDIAC CHANNELOPATHY; CAUSE OF DEATH; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENE; GENE DELETION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; INFANT; KCNH2 GENE; MALE; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NEWBORN; NEXT GENERATION SEQUENCING; PRIORITY JOURNAL; RYR2 GENE; SCN5A GENE; SUDDEN DEATH; ADOLESCENT; CHANNELOPATHY; DNA SEQUENCE; ETIOLOGY; FORENSIC GENETICS; GENETICS; HIGH THROUGHPUT SEQUENCING; MUTATION; PRESCHOOL CHILD; YOUNG ADULT;

ADOLESCENT; ADULT; ANKYRINS; CALSEQUESTRIN; CHANNELOPATHIES; CHILD, PRESCHOOL; COHORT STUDIES; DEATH, SUDDEN; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; FORENSIC GENETICS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INFANT; INFANT, NEWBORN; MALE; MUTATION; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SEQUENCE ANALYSIS, DNA; YOUNG ADULT;

EID: 84936858306     PISSN: 03790738     EISSN: 18726283     Source Type: Journal    
DOI: 10.1016/j.forsciint.2015.06.023     Document Type: Article

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