-
1
-
-
1942536148
-
Drug-induced torsades de pointes and implications for drug development
-
Fenichel RR, Malik M, Antzelevitch C, Sanguinetti M, Roden DM, Priori SG, Ruskin JN, Lipicky RJ, Cantilena LR. Drug-induced torsades de pointes and implications for drug development. J Cardiovasc Electrophysiol. 2004;15:475-495.
-
(2004)
J Cardiovasc Electrophysiol
, vol.15
, pp. 475-495
-
-
Fenichel, R.R.1
Malik, M.2
Antzelevitch, C.3
Sanguinetti, M.4
Roden, D.M.5
Priori, S.G.6
Ruskin, J.N.7
Lipicky, R.J.8
Cantilena, L.R.9
-
2
-
-
0033514263
-
Low penetrance in the long-QT syndrome: Clinical impact
-
Priori SG, Napolitano C, Schwartz PJ. Low penetrance in the long-QT syndrome: clinical impact. Circulation. 1999;99:529-533.
-
(1999)
Circulation
, vol.99
, pp. 529-533
-
-
Priori, S.G.1
Napolitano, C.2
Schwartz, P.J.3
-
3
-
-
0014438985
-
Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibres
-
Noble D, Tsien RW. Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibres. J Physiol (Lond). 1969; 200:205-231.
-
(1969)
J Physiol (Lond)
, vol.200
, pp. 205-231
-
-
Noble, D.1
Tsien, R.W.2
-
4
-
-
0025351245
-
+ current: Differential sensitivity to block by class III antiar- rhythmic agents
-
+ current: differential sensitivity to block by class III antiar- rhythmic agents. J Gen Physiol. 1990;96:195-215.
-
(1990)
J Gen Physiol
, vol.96
, pp. 195-215
-
-
Sanguinetti, M.C.1
Jurkiewicz, N.K.2
-
5
-
-
0025162922
-
Time-dependent outward current in guinea pig ventricular myocytes: Gating kinetics of the delayed rectifier
-
Balser JR, Bennett PB, Roden DM. Time-dependent outward current in guinea pig ventricular myocytes: gating kinetics of the delayed rectifier. J Gen Physiol. 1990;96:835-863.
-
(1990)
J Gen Physiol
, vol.96
, pp. 835-863
-
-
Balser, J.R.1
Bennett, P.B.2
Roden, D.M.3
-
7
-
-
0032066007
-
Taking the idio out of idiosyncratic: Predicting torsades de pointes
-
Roden DM. Taking the idio out of idiosyncratic: predicting torsades de pointes. Pacing Clin Electrophysiol. 1998;21:1029-1034.
-
(1998)
Pacing Clin Electrophysiol
, vol.21
, pp. 1029-1034
-
-
Roden, D.M.1
-
8
-
-
52149123342
-
Feedback remodeling of cardiac potassium current expression: A novel potential mechanism for control of repolarization reserve
-
Xiao L, Xiao J, Luo X, Lin H, Wang Z, Nattel S. Feedback remodeling of cardiac potassium current expression: a novel potential mechanism for control of repolarization reserve. Circulation. 2008;118:983-992.
-
(2008)
Circulation
, vol.118
, pp. 983-992
-
-
Xiao, L.1
Xiao, J.2
Luo, X.3
Lin, H.4
Wang, Z.5
Nattel, S.6
-
9
-
-
31744432337
-
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation
-
Chen JF, Mandel EM, Thomson JM, Wu Q, Callis TE, Hammond SM, Conlon FL, Wang DZ. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet. 2006;38:228-233.
-
(2006)
Nat Genet
, vol.38
, pp. 228-233
-
-
Chen, J.F.1
Mandel, E.M.2
Thomson, J.M.3
Wu, Q.4
Callis, T.E.5
Hammond, S.M.6
Conlon, F.L.7
Wang, D.Z.8
-
10
-
-
34347404509
-
Transcriptional activation by stimulating protein 1 and post-transcriptional repression by muscle-specific microRNAs of IKs-encoding genes and potential implications in regional heterogeneity of their expressions
-
Luo X, Xiao J, Lin H, Li B, Lu Y, Yang B, Wang Z. Transcriptional activation by stimulating protein 1 and post-transcriptional repression by muscle-specific microRNAs of IKs-encoding genes and potential implications in regional heterogeneity of their expressions. J Cell Physiol. 2007;212:358-367.
-
(2007)
J Cell Physiol
, vol.212
, pp. 358-367
-
-
Luo, X.1
Xiao, J.2
Lin, H.3
Li, B.4
Lu, Y.5
Yang, B.6
Wang, Z.7
-
11
-
-
0030056967
-
ks play a role in the reverse rate dependence of class III agents?
-
ks play a role in the reverse rate dependence of class III agents? Circ Res. 1996;78:26-37.
-
(1996)
Circ Res
, vol.78
, pp. 26-37
-
-
Gintant, G.A.1
-
12
-
-
34250378330
-
MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts
-
Xiao J, LuoX, LinH, Zhang Y, LuY, Wang N, Zhang Y, Yang B, Wang Z. MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts. J Biol Chem. 2007;282:12363-12367.
-
(2007)
J Biol Chem
, vol.282
, pp. 12363-12367
-
-
Xiao, J.1
Luo, X.2
Lin, H.3
Zhang, Y.4
Lu, Y.5
Wang, N.6
Zhang, Y.7
Yang, B.8
Wang, Z.9
-
13
-
-
34249729491
-
Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy
-
Tatsuguchi M, Seok HY, Callis TE, Thomson JM, Chen JF, Newman M, Rojas M, Hammond SM, Wang DZ. Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. J Mol Cell Cardiol. 2007;42:1137-1141.
-
(2007)
J Mol Cell Cardiol
, vol.42
, pp. 1137-1141
-
-
Tatsuguchi, M.1
Seok, H.Y.2
Callis, T.E.3
Thomson, J.M.4
Chen, J.F.5
Newman, M.6
Rojas, M.7
Hammond, S.M.8
Wang, D.Z.9
-
14
-
-
50649111705
-
Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart
-
Luo X, Lin H, Pan Z, Xiao J, Zhang Y, Lu Y, Yang B, Wang Z. Down-regulation of miR-1/miR-133 contributes to re-expression of pacemaker channel genes HCN2 and HCN4 in hypertrophic heart. J Biol Chem. 2008;283:20045-20052.
-
(2008)
J Biol Chem
, vol.283
, pp. 20045-20052
-
-
Luo, X.1
Lin, H.2
Pan, Z.3
Xiao, J.4
Zhang, Y.5
Lu, Y.6
Yang, B.7
Wang, Z.8
-
15
-
-
0026488175
-
Prediction of sotalol-induced maximum steady-state QTc prolongation from single-dose administration in healthy volunteers
-
Le Coz F, Funck-Brentano C, Poirier JM, Kibleur Y, Mazoit FX, Jaillon P. Prediction of sotalol-induced maximum steady-state QTc prolongation from single-dose administration in healthy volunteers. Clin Pharmacol Ther. 1992;52:417-426.
-
(1992)
Clin Pharmacol Ther
, vol.52
, pp. 417-426
-
-
Le Coz, F.1
Funck-Brentano, C.2
Poirier, J.M.3
Kibleur, Y.4
Mazoit, F.X.5
Jaillon, P.6
-
16
-
-
0025963987
-
Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes: Mechanism of action
-
Sanguinetti MC, Jurkiewicz NK, Scott A, Siegl PKS. Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes: mechanism of action. Circ Res. 1991;68:77- 84.
-
(1991)
Circ Res
, vol.68
, pp. 77-84
-
-
Sanguinetti, M.C.1
Jurkiewicz, N.K.2
Scott, A.3
Siegl, P.K.S.4
-
17
-
-
0026520509
-
Endothelin enhances delayed potassium current via phos- pholipase C in guinea pig ventricular myocytes
-
Habuchi Y, Tanaka H, Furukawa T, Tsujimura Y, Takahashi H, Yoshimura M. Endothelin enhances delayed potassium current via phos- pholipase C in guinea pig ventricular myocytes. Am J Physiol. 1992;262:H345-H354.
-
(1992)
Am J Physiol
, vol.262
-
-
Habuchi, Y.1
Tanaka, H.2
Furukawa, T.3
Tsujimura, Y.4
Takahashi, H.5
Yoshimura, M.6
-
18
-
-
24744444533
-
ks in human ventricular muscle
-
ks in human ventricular muscle. Circulation. 2005;112:1392-1399.
-
(2005)
Circulation
, vol.112
, pp. 1392-1399
-
-
Jost, N.1
Virag, L.2
Bitay, M.3
Takacs, J.4
Lengyel, C.5
Biliczki, P.6
Nagy, Z.7
Bogats, G.8
Lathrop, D.A.9
Papp, J.G.10
Varro, A.11
-
19
-
-
24744448000
-
ks participation in cardiac repolarization and repolarization reserve
-
ks participation in cardiac repolarization and repolarization reserve. Circulation. 2005;112:1384-1391.
-
(2005)
Circulation
, vol.112
, pp. 1384-1391
-
-
Silva, J.1
Rudy, Y.2
-
20
-
-
0037161355
-
Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes
-
Yang P, Kanki H, Drolet B, Yang T, Wei J, Viswanathan PC, Hohnloser SH, Shimizu W, Schwartz PJ, Stanton MS, Murray KT, Norris K, George ALJ, Roden DM. Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes. Circulation. 2002;105:1943-1948.
-
(2002)
Circulation
, vol.105
, pp. 1943-1948
-
-
Yang, P.1
Kanki, H.2
Drolet, B.3
Yang, T.4
Wei, J.5
Viswanathan, P.C.6
Hohnloser, S.H.7
Shimizu, W.8
Schwartz, P.J.9
Stanton, M.S.10
Murray, K.T.11
Norris, K.12
George, A.L.J.13
Roden, D.M.14
|