Feasibility of a prospective, randomised, open-label, international multicentre, phase III, non-inferiority trial to assess the safety of active surveillance for low risk ductal carcinoma in situ - The LORD study

European Journal of Cancer

Volumn 51, Issue 12, 2015, Pages 1497-1510

  Elshof, Lotte E ^a   Tryfonidis, Konstantinos ^b   Slaets, Leen ^b   Van Leeuwen Stok, A Elise ^c   Skinner, Victoria P ^a   Dif, Nicolas ^b   Pijnappel, Ruud M ^d   Bijker, Nina ^e   Rutgers, Emiel J Th ^a   Wesseling, Jelle ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b EORTC DATA CENTER   (Belgium)

^c BOOG Study Center   (Netherlands)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Active surveillance; Ductal carcinoma in situ; Hormonal therapy; Low grade; Overdiagnosis; Overtreatment; Radiotherapy; Surgery

Indexed keywords

TAMOXIFEN;

ACTIVE SURVEILLANCE; ADULT; ARTICLE; BREAST BIOPSY; CANCER GRADING; CANCER HORMONE THERAPY; CANCER PATIENT; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER SURGERY; CLINICAL EVALUATION; CONSERVATIVE TREATMENT; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC TEST ACCURACY STUDY; DIGITAL MAMMOGRAPHY; EXPLORATORY RESEARCH; FEASIBILITY STUDY; FEMALE; FOLLOW UP; HEALTH CARE QUALITY; HEALTH SURVEY; HUMAN; INTRADUCTAL CARCINOMA; LOW RISK PATIENT; MAJOR CLINICAL STUDY; MASTECTOMY; MULTICENTER STUDY; MULTIMODALITY CANCER THERAPY; NUCLEAR MAGNETIC RESONANCE IMAGING; OPEN STUDY; PATIENT SAFETY; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TRANSLATIONAL RESEARCH; TREATMENT OUTCOME; TUMOR BIOPSY; WIDE EXCISION; AGED; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CLINICAL TRIAL; MIDDLE AGED; NEOPLASM METASTASIS; PATHOLOGY; WATCHFUL WAITING;

ADULT; AGED; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; FEASIBILITY STUDIES; FEMALE; HUMANS; MIDDLE AGED; NEOPLASM METASTASIS; PROSPECTIVE STUDIES; WATCHFUL WAITING;

EID: 84936846896     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2015.05.008     Document Type: Article

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