Genetic pathways in the evolution of breast ductal carcinoma in situ

Journal of Pathology

Volumn 196, Issue 3, 2002, Pages 280-286

  Derenzini, Massimo ^a   Farabegoli, Fulvia ^a   Lidereau, Rosette ^b   Bieche, Ivan ^b   Champeme, Marie Helene ^b   Ceccarelli, Claudio ^a   Santini, Donatella ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b CENTRE RENÉ HUGUENIN   (France)

Author keywords

Ductal carcinoma in situ (DCIS); Genetic alterations; Loss of heterozygosity(LOH)

Indexed keywords

FORMALDEHYDE; PARAFFIN;

ALLELE; ARTICLE; BREAST CARCINOMA; BREAST DUCT; CANCER GROWTH; CANCER INVASION; CANCER STAGING; CARCINOMA IN SITU; CHROMOSOME 11Q; CHROMOSOME 12P; CHROMOSOME 13Q; CHROMOSOME 16Q; CHROMOSOME 17Q; CHROMOSOME 1P; CHROMOSOME 3P; CHROMOSOME 7Q; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; DISSECTION; GENE MUTATION; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROSATELLITE MARKER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STATISTICAL ANALYSIS; STATISTICAL MODEL;

BREAST NEOPLASMS; CARCINOMA IN SITU; CARCINOMA, DUCTAL, BREAST; CHI-SQUARE DISTRIBUTION; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; NEOPLASMS, MULTIPLE PRIMARY; POLYMERASE CHAIN REACTION;

EID: 0036187978     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1048     Document Type: Article

References (26)

1. Intraductal carcinoma of the breast: Follow-up after biopsy only
2. Deletion map of chromosome 16q in ductal carcinoma in situ of the breast: Refining a putative tumor suppressor gene region
3. Molecular analysis of premalignant and carcinoma in situ lesions of the human breast
4. Loss of heterozygosity from the short arm of chromosome 8 is associated with invasive behaviour in breast cancer
5. Loss of heterozygosity at chromosome 6q in preinvasive and early invasive breast carcinomas
6. Loss of heterozygosity at chromosome 9p in ductal carcinoma in situ and invasive carcinoma of the breast
7. Analysis of loss of heterozygosity in 399 premalignant breast lesions at 15 genetic loci
8. The long and the short of chromosome 11 in breast cancer
9. Allelic loss and the progression of breast cancer
10. Genetic progression, histologic grade, and allelic loss in ductal carcinoma in situ of the breast
11. Genetic alterations on chromosome 16 and 17 are important features of ductal carcinoma in situ of the breast and are associated with histologic type
12. Allelic imbalance in the region of the BRCA1 gene in ductal carcinoma in situ of the breast
13. Mutation of the TP53 gene and allelic imbalance at chromosome 17p13 in ductal carcinoma in situ
14. Location of several putative genes possibly involved in human breast cancer progression
15. Loss of chromosome arm 8p loci in prostate cancer: Mapping by quantitative allelic imbalance
16. Genetic alterations in breast cancer
17. Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: Pathological correlations
18. Patterns of loss of heterozygosity at loci from chromosome arm 13q suggest a possible involvement of BRCA2 in sporadic breast tumors
19. Clinical impact of detection of loss of heterozygosity of BRCA1 and BRCA2 markers in sporadic breast cancer
20. Mapping loss of heterozygosity at chromosome 13q: Loss at 13q12-q13 is associated with breast tumour progression and poor prognosis
21. Widespread chromosomal abnormalities in high grade ductal carcinoma in situ of the breast. Comparative genomic hybridization study of pure high-grade DCIS
22. Patterns of allelic loss on chromosome 17 in sporadic breast carcinomas detected by fluorescent-labeled microsatellite analysis
23. Consortium study on 1280 breast carcinomas: Allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters
24. Comparative genomic hybridization of ductal carcinoma in situ of the breast - Evidence of multiple genetic pathways
25. Amplification of growth regulatory genes in intraductal breast cancer is associated with higher nuclear grade but not with the progression to invasiveness