Internalization of GluA2 and the underlying mechanisms of cognitive decline in aged rats following surgery and prolonged exposure to sevoflurane

NeuroToxicology

Volumn 49, Issue , 2015, Pages 94-103

  Hu, Nan ^a,b   Wang, Miaomiao ^a,b   Xie, Keliang ^a,b   Wang, Haiyun ^a,b   Wang, Chenxu ^a,b   Wang, Chao ^a,b   Wang, Chunyan ^a,b   Li, Yize ^a,b   Yu, Yonghao ^a,b   Wang, Guolin ^a,b  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b Tianjin Research Institute of Anesthesiology   (China)

Author keywords

A Amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid receptor; Glutamate receptor subunit 2; Myocyte enhancer factor 2; Orthopedic surgery; Phosphoinositide 3 kinase; Sevoflurane

Indexed keywords

ACTIVITY REGULATED CYTOSKELETON ASSOCIATED PROTEIN; GLUTAMATE RECEPTOR 2; MYOCYTE ENHANCER FACTOR 2; PHOSPHATIDYLINOSITOL 3 KINASE; SEVOFLURANE; AMPA RECEPTOR; ETHER DERIVATIVE; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 2; INHALATION ANESTHETIC AGENT;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; COGNITIVE DEFECT; CONCENTRATION (PARAMETERS); CONDITIONING; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEAR; HIPPOCAMPUS; IMMUNOPRECIPITATION; MALE; MOLECULAR MECHANICS; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; WESTERN BLOTTING; Y-MAZE TEST; ADVERSE EFFECTS; ANIMAL; COGNITION DISORDERS; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; MAZE TEST; METABOLISM; OSTEOTOMY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; POSTOPERATIVE COMPLICATION; SIGNAL TRANSDUCTION; TIME FACTOR; ULTRASTRUCTURE; WISTAR RAT;

RATTUS;

AGING; ANESTHETICS, INHALATION; ANIMALS; COGNITION DISORDERS; CONDITIONING (PSYCHOLOGY); FEAR; GENE EXPRESSION REGULATION; HIPPOCAMPUS; MALE; MAZE LEARNING; METHYL ETHERS; NEURONS; OSTEOTOMY; PHOSPHATIDYLINOSITOL 3-KINASES; POSTOPERATIVE COMPLICATIONS; PROTEIN TRANSPORT; RATS; RATS, WISTAR; RECEPTORS, AMPA; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84936769521     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2015.05.010     Document Type: Article

References (28)

1. Cao J., Tan H., Mi W., Zuo Z. Glutamate transporter type 3 regulates mouse hippocampal GluR1 trafficking. Biochim. Biophys. Acta 2014, 1840(6):1640-1645.
2. Din N., Ahmad I., Ul Haq I., Elahi S., Hoessli D.C., Shakoori A.R. The function of GluR1 and GluR2 in cerebellar and hippocampal LTP and LTD is regulated by interplay of phosphorylation and O-GlcNAc modification. J. Cell. Biochem. 2010, 109(3):585-597.
3. Gibb R., Kolb B. A method for vibratome sectioning of Golgi-Cox stained whole rat brain. J. Neurosci. Methods 1998, 79(1):1-4.
4. He H.J., Wang Y., Le Y., Duan K.M., Yan X.B., Liao Q., Liao Y., Tong J.B., Terrando N., Ouyang W., Ouyang W. Surgery upregulates high mobility group box-1 and disrupts the blood-brain barrier causing cognitive dysfunction in aged rats. CNS Neurosci. Ther. 2012, 18:994-1002.
5. Henley J.M., Wilkinson K.A. AMPA receptor trafficking and the mechanisms underlying synaptic plasticity and cognitive aging. Dialogues Clin. Neurosci. 2013, 15(1):11-27.
6. Hu N., Guo D., Wang H., Xie K., Wang C., Li Y., Wang C., Wang C., Yu Y., Wang G. Involvement of the blood-brain barrier opening in cognitive decline in aged rats following orthopedic surgery and high concentration of sevoflurane inhalation. Brain Res. 2014, 1551:13-24.
7. Joels G., Lamprecht R. Interaction between N-ethylmaleimide-sensitive factor and GluR2 is essential for fear memory formation in lateral amygdala. J. Neurosci. 2010, 30(47):15981-15986.
8. Kapila A.K., Watts H.R., Wang T., Ma D. The impact of surgery and anesthesia on post-operative cognitive decline and Alzheimer's disease development: biomarkers and preventive strategies. J. Alzheimers Dis. 2014, 41(1):1-13.
9. Lee I.H., Culley D.J., Baxter M.G., Xie Z., Tanzi R.E., Crosby G., Tanzi R.E. Spatial memory is intact in aged rats after propofol anesthesia. Anesth. Analg. 2008, 107:1211-1215.
10. Li J., Deng J., Sheng W., Zuo Z. Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice. Pharmacol. Biochem. Behav. 2012, 101(4):564-574.
11. Liu S.J., Gasperini R., Foa L., Small D.H. Amyloid-beta decreases cell-surface AMPA receptors by increasing intracellular calcium and phosphorylation of GluR2. J. Alzheimers Dis. 2010, 21(2):655-666.
12. Lyman M., Lloyd D.G., Ji X., Vizcaychipi M.P., Ma D. Neuroinflammation: the role and consequences. Neurosci. Res. 2014, 79:1-12.
13. Moller J.T., Cluitmans P., Rasmussen L.S., Houx P., Rasmussen H., Canet J., Rabbitt P., Jolles J., Larsen K., Hanning C.D., Langeron O., Johnson T., Lauven P.M., Kristensen P.A., Biedler A., van Beem H., Fraidakis O., Silverstein J.H., Beneken J.E., Gravenstein J.S. Long-term postoperative cognitive dysfunction in the elderly: ISPOCD 1 study. Lancet 1998, 351(9106):857-861.
14. Pac-Soo C., Lloyd D.G., Vizcaychipi M.P., Ma D. Statins: the role in the treatment and prevention of Alzheimer's neurodegeneration. J. Alzheimers Dis. 2011, 27(1):1-10.
15. Rial Verde E.M., Lee-Osbourne J., Worley P.F., Malinow R., Cline H.T. Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission. Neuron 2006 Nov 9, 52(3):461-474.
16. Shen X., Dong Y., Xu Z., Wang H., Miao C., Soriano S.G., Sun D., Baxter M.G., Zhang Y., Xie Z. Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment. Anesthesiology 2013, 118(3):502-515.
17. Terrando N., Eriksson L.I., Ryu J.K., Yang T., Monaco C., Feldmann M., Jonsson Fagerlund M., Charo I.F., Akassoglou K., Maze M. Resolving postoperative neuroinflammation and cognitive decline. Ann. Neurol. 2011, 70:986-995.
18. Vizcaychipi M.P., Xu L., Barreto G.E., Ma D., Maze M., Giffard R.G. Heat shock protein 72 overexpression prevents early postoperative memory decline after orthopedic surgery under general anesthesia in mice. Anesthesiology 2011, 114:891-900.
19. Vizcaychipi M.P., Watts H.R., O'Dea K.P., Lloyd D.G., Penn J.W., Wan Y., Pac-Soo C., Takata M., Ma D. The therapeutic potential of atorvastatin in a mouse model of postoperative cognitive decline. Ann. Surg. 2014, 259(6):1235-1244.
20. Wang G., Gilbert J., Man H.Y. AMPA receptor trafficking in homeostatic synaptic plasticity: functional molecules and signaling cascades. Neural Plasticity 2012, 825364.
21. Wang H., Wang G., Wang C., Wei Y., Wen Z., Wang C., Zhu A. The early stage formation of PI3K-AMPAR GluR2 subunit complex facilitates the long term neuroprotection induced by Propofol post-conditioning in rats. PLoS One 2013, 8(6):e65187.
22. Wang Z., Park S.H., Zhao H., Peng S., Zuo Z. A critical role of glutamate transporter type 3 in the learning and memory of mice. Neurobiol. Learn Mem. 2014, 114C:70-80.
23. Wenthold R.J., Petralia R.S., Blahos J., Niedzielski A.S. Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons. J. Neurosci. 1996, 16(6):1982-1989.
24. Zhang G., Dong Y., Zhang B., Ichinose F., Wu X., Culley D.J., Crosby G., Tanzi R.E., Xie Z. Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J. Neurosci. 2008, 28:4551-4560.
25. Zhang L., Zhang J., Dong Y., Swain C.A., Zhang Y., Xie Z. The potential dual effects of sevoflurane on AKT/GSK3β signaling pathway. Med. Gas Res. 2014, 4(1):5.
26. Zhao H., Sapolsky R.M., Steinberg G.K. Phosphoinositide-3-Kinase/Akt survival signal pathways are implicated in neuronal survival after stroke. Mol. Neurobiol. 2006, 34(3):249-269.
27. Zhao Y., Zhao H., Lobo N., Guo X., Gentleman S.M., Ma D. Celastrol enhances cell viability and inhibits amyloid-β production induced by lipopolysaccharide in vitro. J. Alzheimers Dis. 2014, 41(3):835-844.
28. Zhou Z., Ma D. Anaesthetics-induced neurotoxicity in developing brain: an update on preclinical evidence. Brain Sci. 2014, 4(1):136-149.