Celastrol enhances cell viability and inhibits amyloid-β production induced by lipopolysaccharide in vitro

Journal of Alzheimer's disease : JAD

Volumn 41, Issue 3, 2014, Pages 835-844

  Zhao, Yan ^a   Zhao, Hailin ^a   Lobo, Niyati ^a   Guo, Xiangyang ^a   Gentleman, Steve M ^a   Ma, Daqing ^a  

^a CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

Author keywords

Alzheimer's disease; amyloid ; celastrol; cell signal; lipopolysaccharide; neuroinflammation

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; CYCLOOXYGENASE 2; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE; HEAT SHOCK PROTEIN 70; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TRIPTERINE; TRITERPENE;

CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; NEUROBLASTOMA; PATHOLOGY; TIME; TUMOR CELL LINE;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOOXYGENASE 2; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASES; HSP70 HEAT-SHOCK PROTEINS; HUMANS; HYDROGEN PEROXIDE; LIPOPOLYSACCHARIDES; NEUROBLASTOMA; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; TIME FACTORS; TRANSFECTION; TRITERPENES;

EID: 84907975871     PISSN: None     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-131799     Document Type: Article

References (0)