Crystallization Kinetics of Indomethacin/Polyethylene Glycol Dispersions Containing High Drug Loadings

Molecular Pharmaceutics

Volumn 12, Issue 7, 2015, Pages 2493-2504

  Duong, Tu Van ^a,c   Van Humbeeck, Jan ^b   Van Den Mooter, Guy ^a  

^a DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c HANOI UNIVERSITY OF PHARMACY   (Viet Nam)

Author keywords

amorphous; crystalline; crystallization; drug loading; indomethacin; kinetics; modulated differential scanning calorimetry; phase separation; polyethylene glycol; solid dispersions; X ray diffraction

Indexed keywords

INDOMETACIN; MACROGOL 6000; POLYMER; MACROGOL DERIVATIVE; POWDER;

ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; GLASS TRANSITION TEMPERATURE; HYDROGEN BOND; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHASE SEPARATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REPRODUCIBILITY; SOLUBILIZATION; X RAY DIFFRACTION; CHEMISTRY; KINETICS; POWDER; PROCEDURES; SOLUBILITY;

CALORIMETRY, DIFFERENTIAL SCANNING; CRYSTALLIZATION; INDOMETHACIN; KINETICS; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS; POLYMERS; POWDERS; SOLUBILITY; X-RAY DIFFRACTION;

EID: 84936746042     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.5b00299     Document Type: Article

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