Endothelial dimethylarginine dimethylaminohydrolase 1 is an important regulator of angiogenesis but does not regulate vascular reactivity or hemodynamic homeostasis

Circulation

Volumn 131, Issue 25, 2015, Pages 2217-2225

  Dowsett, Laura ^a   Piper, Sophie ^a   Slaviero, Anna ^a   Dufton, Neil ^b   Wang, Zhen ^a   Boruc, Olga ^a   Delahaye, Matthew ^a   Colman, Lucy ^a   Kalk, Eliza ^a   Tomlinson, James ^a   Birdsey, Graeme ^b   Randi, Anna M ^b   Leiper, James ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Angiogenesis; Endothelium; Neovascularization; Nitric oxide; Physiologic

Indexed keywords

DIMETHYLARGININASE; ENDOTHELIAL DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1; N(G),N(G) DIMETHYLARGININE; UNCLASSIFIED DRUG; AMIDASE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD LEVEL; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR RISK; CONTROLLED STUDY; ENDOTHELIUM CELL; EX VIVO STUDY; HEMODYNAMICS; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; DEFICIENCY; ENZYMOLOGY; HOMEOSTASIS; KNOCKOUT MOUSE; PHYSIOLOGY; VASCULAR ENDOTHELIUM;

AMIDOHYDROLASES; ANIMALS; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HEMODYNAMICS; HOMEOSTASIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOVASCULARIZATION, PHYSIOLOGIC;

EID: 84936145001     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.114.015064     Document Type: Article

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