Alanine-glyoxylate aminotransferase-2 metabolizes endogenous methylarginines, regulates NO, and controls blood pressure

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 32, Issue 12, 2012, Pages 2892-2900

  Caplin, Ben ^a,b   Wang, Zhen ^a   Slaviero, Anna ^a   Tomlinson, James ^a   Dowsett, Laura ^a   Delahaye, Mathew ^a   Salama, Alan ^b   Wheeler, David C ^b   Leiper, James ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

alanine glyoxylate aminotransferase 2; asymmetric dimethylarginine; hypertension; kidney; NO

Indexed keywords

ALANINE GLYOXYLATE AMINOTRANSFERASE; ALANINE GLYOXYLATE AMINOTRANSFERASE 2; ARGININE DERIVATIVE; DIMETHYLARGININASE; DIMETHYLARGININE; ISOLEUCINE; METHYLARGININE DERIVATIVE; NITRIC OXIDE; THREONINE; UNCLASSIFIED DRUG; VALINE;

ADULT; ALLELE; AMINO ACID METABOLISM; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CLINICAL ARTICLE; DEAMINATION; DIASTOLIC BLOOD PRESSURE; ENZYME METABOLISM; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; HYPERTENSION; KIDNEY; KNOCKOUT MOUSE; MALE; META ANALYSIS (TOPIC); MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADULT; ANIMALS; ARGININE; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; HYPERTENSION; KIDNEY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; MITOCHONDRIA; NITRIC OXIDE; TRANSAMINASES;

EID: 84870063190     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.254078     Document Type: Article

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