Vascular endothelial-specific dimethylarginine dimethylaminohydrolase-1- deficient mice reveal that vascular endothelium plays an important role in removing asymmetric dimethylarginine

Circulation

Volumn 120, Issue 22, 2009, Pages 2222-2229

  Hu, Xinli ^a   Xu, Xin ^a   Zhu, Guangshuo ^a   Atzler, Dorothee ^b   Kimoto, Masumi ^c   Chen, Ju ^d   Schwedhelm, Edzard ^b   Lüneburg, Nicole ^b   Böger, Rainer H ^b   Zhang, Ping ^a   Chen, Yingjie ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Asymmetric dimethylarginine; Dimethylarginine dimethylaminohydrolase; Knockout mice; Nitric oxide

Indexed keywords

ACETYLCHOLINE; DIMETHYLARGININASE; DIMETHYLARGININASE 1; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO GROWTH; ENDOTHELIUM CELL; FEMALE; GENE DELETION; HEART VENTRICLE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SYSTOLIC BLOOD PRESSURE; TISSUE LEVEL; VASCULAR ENDOTHELIUM; VASODILATATION;

ACETYLCHOLINE; AMIDOHYDROLASES; ANIMALS; AORTA; ARGININE; BRAIN; CHOLINERGIC AGENTS; ENDOTHELIUM, VASCULAR; FEMALE; HYPERTENSION; KIDNEY; LIVER; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SKELETAL; NITRIC OXIDE; VASODILATION; VENTRICULAR FUNCTION, LEFT;

EID: 73449121413     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.108.819912     Document Type: Article

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