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Volumn 12, Issue 4, 2015, Pages 474-482

CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not

Author keywords

CXCL12; CXCR4; CXCR7; hepatocellular carcinoma; prognosis

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR7; MESSENGER RNA; PLERIXAFOR; CHEMOKINE RECEPTOR CXCR; CXCR4 PROTEIN, HUMAN; CXCR7 PROTEIN, HUMAN; TUMOR PROTEIN;

EID: 84936141104     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2014.102     Document Type: Article
Times cited : (42)

References (41)
  • 2
    • 42949086433 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of liver injury
    • Malhi H, Gores GJ. Cellular and molecular mechanisms of liver injury. Gastroenterology 2008; 134: 1641-1654
    • (2008) Gastroenterology , vol.134 , pp. 1641-1654
    • Malhi, H.1    Gores, G.J.2
  • 3
    • 34548850886 scopus 로고    scopus 로고
    • Chemokines in hepatitis C virus infection: Pathogenesis, prognosis and therapeutics
    • Wald O, Weiss ID, Galun E, Peled A. Chemokines in hepatitis C virus infection: pathogenesis, prognosis and therapeutics. Cytokine 2007; 39: 50-62
    • (2007) Cytokine , vol.39 , pp. 50-62
    • Wald, O.1    Weiss, I.D.2    Galun, E.3    Peled, A.4
  • 4
    • 77951490243 scopus 로고    scopus 로고
    • Chemokines and hepatocellular carcinoma
    • Huang F, Geng XP. Chemokines and hepatocellular carcinoma. World J Gastroenterol 2010; 16: 1832-1836
    • (2010) World J Gastroenterol , vol.16 , pp. 1832-1836
    • Huang, F.1    Geng, X.P.2
  • 5
    • 38549175201 scopus 로고    scopus 로고
    • Immunohistochemical expression of stromal cell-derived factor-1 (SDF-1) and CXCR4 ligand receptor system in hepatocellular carcinoma
    • Li W, Gomez E, Zhang Z. Immunohistochemical expression of stromal cell-derived factor-1 (SDF-1) and CXCR4 ligand receptor system in hepatocellular carcinoma. J Exp Clin Cancer Res 2007; 26: 527-533
    • (2007) J Exp Clin Cancer Res , vol.26 , pp. 527-533
    • Li, W.1    Gomez, E.2    Zhang, Z.3
  • 6
    • 63849150544 scopus 로고    scopus 로고
    • Roles of chemokine receptor 4 (CXCR4) and chemokine ligand 12 (CXCL12) in metastasis of hepatocellular carcinoma cells
    • Liu H, Pan Z, Li A. Roles of chemokine receptor 4 (CXCR4) and chemokine ligand 12 (CXCL12) in metastasis of hepatocellular carcinoma cells. Cell Mol Immunol 2008; 5: 373-378
    • (2008) Cell Mol Immunol , vol.5 , pp. 373-378
    • Liu, H.1    Pan, Z.2    Li, A.3
  • 7
    • 33745888428 scopus 로고    scopus 로고
    • Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4
    • Schimanski CC, Bahre R, Gockel I. Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4. Br J Cancer 2006; 95: 210-217
    • (2006) Br J Cancer , vol.95 , pp. 210-217
    • Schimanski, C.C.1    Bahre, R.2    Gockel, I.3
  • 8
    • 67650246591 scopus 로고    scopus 로고
    • Chemokine receptor CXCR4 expression in hepatocellular carcinoma patients increases the risk of bone metastases and poor survival
    • Xiang ZL, Zeng ZC, Tang ZY, Fan J, Zhuang PY, Liang Y, et al. Chemokine receptor CXCR4 expression in hepatocellular carcinoma patients increases the risk of bone metastases and poor survival. BMC Cancer 2009; 9: 176
    • (2009) BMC Cancer , vol.9 , pp. 176
    • Xiang, Z.L.1    Zeng, Z.C.2    Tang, Z.Y.3    Fan, J.4    Zhuang, P.Y.5    Liang, Y.6
  • 9
    • 75149186207 scopus 로고    scopus 로고
    • Increased expression of vascular endothelial growth factor-C and nuclear CXCR4 in hepatocellular carcinoma is correlated with lymph node metastasis and poor outcome
    • Xiang Z, Zeng Z, Tang Z, Fan J, Sun H, Wu W, et al. Increased expression of vascular endothelial growth factor-C and nuclear CXCR4 in hepatocellular carcinoma is correlated with lymph node metastasis and poor outcome. Cancer J 2009; 15: 519-525
    • (2009) Cancer J , vol.15 , pp. 519-525
    • Xiang, Z.1    Zeng, Z.2    Tang, Z.3    Fan, J.4    Sun, H.5    Wu, W.6
  • 10
    • 83255194128 scopus 로고    scopus 로고
    • CXCR7 is up-regulated in human and murine hepatocellular carcinoma and is specifically expressed by endothelial cells
    • Monnier J, Boissan M, LHelgoualch A. CXCR7 is up-regulated in human and murine hepatocellular carcinoma and is specifically expressed by endothelial cells. Eur J Cancer 2012; 48: 138-148
    • (2012) Eur J Cancer , vol.48 , pp. 138-148
    • Monnier, J.1    Boissan, M.2    Lhelgoualch, A.3
  • 11
    • 77950654038 scopus 로고    scopus 로고
    • Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells
    • Zheng K, Li HY, Su XL, Wang XY, Tian T, Li F, et al. Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells. J Exp Clin Cancer Res 2010; 29: 31
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 31
    • Zheng, K.1    Li, H.Y.2    Su, X.L.3    Wang, X.Y.4    Tian, T.5    Li, F.6
  • 12
    • 27444443142 scopus 로고    scopus 로고
    • The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes
    • Balabanian K, Lagane B, Infantino S. The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J Biol Chem 2005; 280: 35760-35766
    • (2005) J Biol Chem , vol.280 , pp. 35760-35766
    • Balabanian, K.1    Lagane, B.2    Infantino, S.3
  • 13
    • 35648945337 scopus 로고    scopus 로고
    • Summers BC CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-Associated vasculature
    • Miao Z, Luker KE, Summers BC CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-Associated vasculature. Proc Natl Acad Sci USA 2007; 104: 15735-15740
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15735-15740
    • Miao, Z.1    Luker, K.E.2
  • 14
    • 42949133032 scopus 로고    scopus 로고
    • The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer
    • Wang J, Shiozawa Y, Wang J. The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer. J Biol Chem 2008; 283: 4283-4294
    • (2008) J Biol Chem , vol.283 , pp. 4283-4294
    • Wang, J.1    Shiozawa, Y.2    Wang, J.3
  • 15
    • 75149142302 scopus 로고    scopus 로고
    • Regulation of expression of stromalderived factor-1 receptors: CXCR4 and CXCR7 in human rhabdomyosarcomas
    • Tarnowski M, Grymula K, Reca R. Regulation of expression of stromalderived factor-1 receptors: CXCR4 and CXCR7 in human rhabdomyosarcomas. Mol Cancer Res 2010; 8: 1-14
    • (2010) Mol Cancer Res , vol.8 , pp. 1-14
    • Tarnowski, M.1    Grymula, K.2    Reca, R.3
  • 16
    • 77951088905 scopus 로고    scopus 로고
    • The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects
    • Hattermann K, Held-Feindt J, Lucius R. The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects. Cancer Res 2010; 70: 3299-3308
    • (2010) Cancer Res , vol.70 , pp. 3299-3308
    • Hattermann, K.1    Held-Feindt, J.2    Lucius, R.3
  • 17
    • 0035282432 scopus 로고    scopus 로고
    • Involvement of chemokine receptors in breast cancer metastasis
    • Müller A, Homey B, Soto H. Involvement of chemokine receptors in breast cancer metastasis. Nature 2001; 410: 50-56
    • (2001) Nature , vol.410 , pp. 50-56
    • Müller, A.1    Homey, B.2    Soto, H.3
  • 18
    • 0028202481 scopus 로고
    • The molecular biology of leukocyte chemoattractant receptors
    • Murphy PM. The molecular biology of leukocyte chemoattractant receptors. Annu Rev Immunol 1994; 12: 593-633
    • (1994) Annu Rev Immunol , vol.12 , pp. 593-633
    • Murphy, P.M.1
  • 20
    • 33748474838 scopus 로고    scopus 로고
    • A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development
    • Burns JM, Summers BC, Wang Y, Melikian A, Berahovich R, Miao Z, et al. A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med 2006; 203: 2201-2213
    • (2006) J Exp Med , vol.203 , pp. 2201-2213
    • Burns, J.M.1    Summers, B.C.2    Wang, Y.3    Melikian, A.4    Berahovich, R.5    Miao, Z.6
  • 21
    • 47249149222 scopus 로고    scopus 로고
    • CXCR7, CXCR4 and CXCL12, an eccentric trio
    • Thelen M, Thelen S. CXCR7, CXCR4 and CXCL12, an eccentric trio? J Neuroimmunol 2008; 198: 9-13
    • (2008) J Neuroimmunol , vol.198 , pp. 9-13
    • Thelen, M.1    Thelen, S.2
  • 22
    • 35548996783 scopus 로고    scopus 로고
    • Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7
    • Sierro F, Biben C, Martínez-Muñoz L, Mellado M, Ransohoff RM, Li M, et al. Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci USA 2007; 104: 14759-14764
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14759-14764
    • Sierro, F.1    Biben, C.2    Martínez-Muñoz, L.3    Mellado, M.4    Ransohoff, R.M.5    Li, M.6
  • 23
    • 78049487451 scopus 로고    scopus 로고
    • Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas
    • Grymula K, Tarnowski M, Wysoczynski M, Drukala J, Barr FG, Ratajczak J, et al. Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas. Int J Cancer 2010; 127: 2554-2568
    • (2010) Int J Cancer , vol.127 , pp. 2554-2568
    • Grymula, K.1    Tarnowski, M.2    Wysoczynski, M.3    Drukala, J.4    Barr, F.G.5    Ratajczak, J.6
  • 25
    • 70349234110 scopus 로고    scopus 로고
    • Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands
    • Zabel BA, Wang Y, Lewén S, Berahovich RD, Penfold ME, Zhang P, et al. Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands. J Immunol 2009; 183: 3204-3211
    • (2009) J Immunol , vol.183 , pp. 3204-3211
    • Zabel, B.A.1    Wang, Y.2    Lewén, S.3    Berahovich, R.D.4    Penfold, M.E.5    Zhang, P.6
  • 26
    • 66649093881 scopus 로고    scopus 로고
    • Higher expression of chemokine receptor CXCR7 is linked to early and metastatic recurrence in pathological stage i nonsmall cell lung cancer
    • Iwakiri S, Mino N, Takahashi T, Sonobe M, Nagai S, Okubo K, et al. Higher expression of chemokine receptor CXCR7 is linked to early and metastatic recurrence in pathological stage I nonsmall cell lung cancer. Cancer 2009; 115: 2580-2593
    • (2009) Cancer , vol.115 , pp. 2580-2593
    • Iwakiri, S.1    Mino, N.2    Takahashi, T.3    Sonobe, M.4    Nagai, S.5    Okubo, K.6
  • 28
    • 84884132303 scopus 로고    scopus 로고
    • Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases
    • Portella L, Vitale R, de Luca S, DAlterio C, Ieranò C, Napolitano M, et al. Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases. PLoS One 2013; 13: 8
    • (2013) PLoS One , vol.13 , pp. 8
    • Portella, L.1    Vitale, R.2    De Luca, S.3    Dalterio, C.4    Ieranò, C.5    Napolitano, M.6
  • 29
    • 17344374988 scopus 로고    scopus 로고
    • Loss of chemokine SDF-1alpha-mediated CXCR4 signalling and receptor internalization in human hepatoma cell line HepG2
    • Mitra P, De A, Ethier MF, Mimori K, Kodys K, Shibuta K, et al. Loss of chemokine SDF-1alpha-mediated CXCR4 signalling and receptor internalization in human hepatoma cell line HepG2. Cell Signal 2001; 13: 311-319
    • (2001) Cell Signal , vol.13 , pp. 311-319
    • Mitra, P.1    De, A.2    Ethier, M.F.3    Mimori, K.4    Kodys, K.5    Shibuta, K.6
  • 30
    • 0032833131 scopus 로고    scopus 로고
    • Maturation decreases responsiveness of human bone marrow B lineage cells to stromalderived factor 1 (SDF-1
    • Fedyk ER, Ryan DH, Ritterman I, Springer TA. Maturation decreases responsiveness of human bone marrow B lineage cells to stromalderived factor 1 (SDF-1). J Leuk Biol 1999; 66: 667-673
    • (1999) J Leuk Biol , vol.66 , pp. 667-673
    • Fedyk, E.R.1    Ryan, D.H.2    Ritterman, I.3    Springer, T.A.4
  • 31
    • 0033231096 scopus 로고    scopus 로고
    • SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells
    • Honczarenko M, Douglas RS, Mathias C, Lee B, Ratajczak MZ, Silberstein LE. SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells. Blood 1999; 94: 2990-2998
    • (1999) Blood , vol.94 , pp. 2990-2998
    • Honczarenko, M.1    Douglas, R.S.2    Mathias, C.3    Lee, B.4    Ratajczak, M.Z.5    Silberstein, L.E.6
  • 32
    • 33846985321 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1/chemokine (C-X-C motif) ligand 12 stimulates human hepatoma cell growth, migration, and invasion
    • Sutton A, Friand V, Brulé-Donneger S, Chaigneau T, Ziol M, Sainte-Catherine O, et al. Stromal cell-derived factor-1/chemokine (C-X-C motif) ligand 12 stimulates human hepatoma cell growth, migration, and invasion. Mol Cancer Res 2007; 5: 21-33
    • (2007) Mol Cancer Res , vol.5 , pp. 21-33
    • Sutton, A.1    Friand, V.2    Brulé-Donneger, S.3    Chaigneau, T.4    Ziol, M.5    Sainte-Catherine, O.6
  • 34
    • 23844513413 scopus 로고    scopus 로고
    • Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: Pivotal role of the SDF-1-CXCR4 axis
    • Kucia M, Reca R, Miekus K, Wanzeck J, Wojakowski W, Janowska-Wieczorek A, et al. Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis. Stem Cells 2005; 23: 879-894
    • (2005) Stem Cells , vol.23 , pp. 879-894
    • Kucia, M.1    Reca, R.2    Miekus, K.3    Wanzeck, J.4    Wojakowski, W.5    Janowska-Wieczorek, A.6
  • 35
    • 79958845447 scopus 로고    scopus 로고
    • High expression of CXCR7 combined with Alpha fetoprotein in hepatocellular carcinoma correlates with extrahepatic metastasis to lung after hepatectomy
    • Xue TC, Han D, Chen RX, Zou JH, Wang Y, Tang ZY, et al. High expression of CXCR7 combined with Alpha fetoprotein in hepatocellular carcinoma correlates with extrahepatic metastasis to lung after hepatectomy. Asian Pac J Cancer Prev 2011; 12: 657-663
    • (2011) Asian Pac J Cancer Prev , vol.12 , pp. 657-663
    • Xue, T.C.1    Han, D.2    Chen, R.X.3    Zou, J.H.4    Wang, Y.5    Tang, Z.Y.6
  • 36
    • 67650349084 scopus 로고    scopus 로고
    • CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling
    • Levoye A, Balabanian K, Baleux F, Bachelerie F, Lagane B. CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling. Blood 2009; 113: 6085-6093
    • (2009) Blood , vol.113 , pp. 6085-6093
    • Levoye, A.1    Balabanian, K.2    Baleux, F.3    Bachelerie, F.4    Lagane, B.5
  • 40
    • 84869087515 scopus 로고    scopus 로고
    • Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells
    • Luker KE, Lewin SA, Mihalko LA, Schmidt BT, Winkler JS, Coggins NL, et al. Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells. Oncogene 2012; 31: 4750-4758
    • (2012) Oncogene , vol.31 , pp. 4750-4758
    • Luker, K.E.1    Lewin, S.A.2    Mihalko, L.A.3    Schmidt, B.T.4    Winkler, J.S.5    Coggins, N.L.6
  • 41
    • 80052768977 scopus 로고    scopus 로고
    • CXCR7/CXCR4 heterodimer constitutive lyrecruits beta-Arrestin to enhance cell migration
    • de Caillot FM, Kazmi MA, Lin Y, Ray-Saha S, Sakmar TP, Sachdev P. CXCR7/CXCR4 heterodimer constitutive lyrecruits beta-Arrestin to enhance cell migration. J Biol Chem 2011; 286: 32188-32197
    • (2011) J Biol Chem , vol.286 , pp. 32188-32197
    • De Caillot, F.M.1    Kazmi, M.A.2    Lin, Y.3    Ray-Saha, S.4    Sakmar, T.P.5    Sachdev, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.