Comprehensive analysis of disease-related genes in chronic lymphocytic leukemia by multiplex PCR-based next generation sequencing

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Vollbrecht, Claudia ^a,b,c   Mairinger, Fabian Dominik ^d   Koitzsch, Ulrike ^a,b,c   Peifer, Martin ^c   Koenig, Katharina ^a,b,c   Heukamp, Lukas Carl ^a,b,f,g   Crispatzu, Giuliano ^a,b,e   Wilden, Laura ^a,b   Kreuzer, Karl Anton ^a,b   Hallek, Michael ^a,b   Odenthal, Margarete ^a,b,c   Herling, Carmen Diana ^a,b   Buettner, Reinhard ^a,b,c  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d UNIVERSITY HOSPITAL ESSEN   (Germany)

^e UNIVERSITY OF COLOGNE   (Germany)

^f Institute of Hematopathology Hamburg   (Germany)

^g NEO New Oncology GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; B LYMPHOCYTE RECEPTOR; CELL DNA; EXPORTIN 1; GLYCINE; HISTIDINE; ISOLEUCINE; MYELOID DIFFERENTIATION FACTOR 88; NOTCH1 RECEPTOR; PROTEIN DDX3X; PROTEIN KINASE ZAP 70; PROTEIN P53; PROTEIN SF3B1; PROTEIN TYROSINE PHOSPHATASE SHP 1; TUMOR MARKER; UNCLASSIFIED DRUG; VALINE;

ADULT; ADVANCED CANCER; AGED; ALGORITHM; AMPLICON; ANALYTICAL EQUIPMENT; ARTICLE; CANCER PROGNOSIS; CHRONIC LYMPHATIC LEUKEMIA; COMPUTER PROGRAM; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENE LIBRARY; GENE MUTATION; GENETIC ANALYSIS; GENETIC CODE; HIGH THROUGHPUT SEQUENCING; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATIONAL ANALYSIS; NEXT GENERATION SEQUENCING; SIGNAL TRANSDUCTION; VERY ELDERLY; GENETIC ASSOCIATION STUDY; GENETIC VARIATION; GENETICS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MIDDLE AGED; MUTATION; PROCEDURES; PROGNOSIS; SENSITIVITY AND SPECIFICITY; STANDARDS;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; GENE LIBRARY; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATION; PROGNOSIS; SENSITIVITY AND SPECIFICITY;

EID: 84936131078     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0129544     Document Type: Article

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