Targeted resequencing for analysis of clonal composition of recurrent gene mutations in chronic lymphocytic leukaemia

British Journal of Haematology

Volumn 163, Issue 4, 2013, Pages 496-500

  Jethwa, Alexander ^a   Hüllein, Jennifer ^a   Stolz, Tatjana ^a   Blume, Carolin ^a   Sellner, Leopold ^a,b   Jauch, Anna ^b   Sill, Martin ^a   Kater, Arnon P ^c   te Raa, G Doreen ^c   Geisler, Christian ^d   van Oers, Marinus ^c   Dietrich, Sascha ^b   Dreger, Peter ^b   Ho, Anthony D ^b   Paruzynski, Anna ^a   Schmidt, Manfred ^a   von Kalle, Christof ^a   Glimm, Hanno ^a   Zenz, Thorsten ^a,b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Chronic lymphocytic leukaemia; Convergent mutation; NOTCH1; SF3B1; TP53

Indexed keywords

B RAF KINASE; K RAS PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; NOTCH1 RECEPTOR; PROTEIN P53; TRANSCRIPTION FACTOR EZH2;

ARTICLE; BRAF GENE; CHROMOSOME 17P; CHROMOSOME DELETION; CHRONIC LYMPHATIC LEUKEMIA; COHORT ANALYSIS; CONTROLLED STUDY; EZH2 GENE; GENE; GENE FREQUENCY; GENE MUTATION; GENE SEGREGATION; GENETIC ANALYSIS; HIGH RISK PATIENT; HUMAN; KRAS GENE; MAJOR CLINICAL STUDY; MYD88 GENE; NEXT GENERATION SEQUENCING; NOTCH1 GENE; NRAS GENE; PIK3CA GENE; PRIORITY JOURNAL; SF3B1 GENE; SOMATIC MUTATION; TP53 GENE;

CHRONIC LYMPHOCYTIC LEUKAEMIA; CONVERGENT MUTATION; NOTCH1; SF3B1; TP53;

COHORT STUDIES; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MUTATION; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION;

EID: 84886392472     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.12539     Document Type: Article

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