Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage

American Journal of Physiology - Renal Physiology

Volumn 309, Issue 1, 2015, Pages F79-F87

  Sas, Kelli M ^b   Yin, Hong ^c   Fitzgibbon, Wayne R ^b   Baicu, Catalin F ^b   Zile, Michael R ^a,b   Steele, Stacy L ^a,b   Amria, May ^b   Saigusa, Takamitsu ^b   Funk, Jason ^b   Bunni, Marlene A ^b   Siegal, Gene P ^d,e   Siroky, Brian J ^c   Bissler, John J ^c   Bell, P Darwin ^a,b  

^a RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e University of Alabama at Birmingham   (United States)

Author keywords

Diabetes; Epithelialto mesenchymal transition; Polycystic kidney disease; Streptozotocin; Wnt

Indexed keywords

STREPTOZOCIN; TAMOXIFEN; WNT PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYSTOGENESIS; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HYPERGLYCEMIA; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY TUBULE; MALE; MOUSE; NONHUMAN; POLYURIA; PRIORITY JOURNAL; PROTEINURIA; WNT SIGNALING PATHWAY; ANIMAL; COMPLICATION; HEMODYNAMICS; KIDNEY; KIDNEY FUNCTION TEST; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; POLYCYSTIC KIDNEY DISEASES; RANDOMIZATION;

ANIMALS; CELL PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HEMODYNAMICS; HYPERGLYCEMIA; KIDNEY; KIDNEY FUNCTION TESTS; MALE; MICE, KNOCKOUT; POLYCYSTIC KIDNEY DISEASES; RANDOM ALLOCATION; WNT PROTEINS;

EID: 84936095707     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00652.2014     Document Type: Article

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