Antitumor and antimetastatic actions of xanthoangelol and 4-hydroxyderricin isolated from Angelica keiskei roots through the inhibited activation and differentiation of M2 macrophages

Phytomedicine

Volumn 22, Issue 7-8, 2015, Pages 759-767

  Sumiyoshi, Maho ^a   Taniguchi, Masahiko ^b   Baba, Kimiye ^b   Kimura, Yoshiyuki ^a  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Antimetastatic; Antitumor; Chalcones; M2 macrophage; Stat3

Indexed keywords

4 HYDROXYDERRICIN; ANTIMETASTATIC AGENT; ANTINEOPLASTIC AGENT; CHALCONE DERIVATIVE; CISPLATIN; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; MONOCYTE CHEMOTACTIC PROTEIN 1; STAT3 PROTEIN; UNCLASSIFIED DRUG; XANTHOANGELOL; 4-HYDROXYDERRICIN; CCL2 PROTEIN, HUMAN; CHALCONE; IL10 PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN;

ANGELICA; ANGELICA KEISKEI; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BODY WEIGHT; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG ISOLATION; DRUG MECHANISM; FOOD INTAKE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER METASTASIS; LUNG METASTASIS; MACROPHAGE ACTIVATION; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; ORGAN WEIGHT; OSTEOSARCOMA; PLANT ROOT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; ANALOGS AND DERIVATIVES; ANIMAL; C3H MOUSE; CELL LINE; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; MACROPHAGE; METABOLISM; PATHOLOGY;

ANGELICA KEISKEI; MUS;

ANGELICA; ANIMALS; ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL DIFFERENTIATION; CELL LINE; CHALCONE; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; HUMANS; INTERLEUKIN-10; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE, INBRED C3H; OSTEOSARCOMA; PLANT ROOTS; STAT3 TRANSCRIPTION FACTOR;

EID: 84935924748     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2015.05.005     Document Type: Article

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