Circulating MicroRNAs: Potential and Emerging Biomarkers for Diagnosis of Cardiovascular and Cerebrovascular Diseases

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Li, Meng ^a   Zhang, Junping ^a  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; BIOLOGICAL MARKER;

ACUTE HEART INFARCTION; ANGIOGENESIS; ATRIAL FIBRILLATION; BODY FLUID; CARDIOMYOPATHY; CARDIOVASCULAR DISEASE; CEREBROVASCULAR ACCIDENT; CEREBROVASCULAR DISEASE; CORONARY ARTERY DISEASE; DISEASE MARKER; GENE EXPRESSION; HEART FAILURE; HEART INFARCTION; HUMAN; HYPERTENSION; NONHUMAN; REGULATORY MECHANISM; REVIEW; ANIMAL; BLOOD; CEREBROVASCULAR DISORDERS; HEART DISEASES;

ANIMALS; BIOMARKERS; CEREBROVASCULAR DISORDERS; HEART DISEASES; HUMANS; HYPERTENSION; MICRORNAS;

EID: 84935918026     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/730535     Document Type: Review

References (72)

1. R. C. Lee, R. L. Feinbaum, and V. Ambros, "The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14, " Cell, vol. 75, no. 5, pp. 843-854, 1993.
2. R. I. Gregory, K.-P. Yan, G. Amuthan, et al., "TheMicroprocessor complex mediates the genesis of microRNAs, " Nature, vol. 432, no. 7014, pp. 235-240, 2004.
3. R. I. Gregory, T. P. Chendrimada, N. Cooch, and R. Shiekhattar, "Human RISC couples microRNA biogenesis and posttranscriptional gene silencing, " Cell, vol. 123, no. 4, pp. 631-640, 2005.
4. X. Liu, D.-Y. Jin, M. T. McManus, and Z. Mourelatos, "Precursor microRNA-programmed silencing complex assembly pathways in mammals, " Molecular Cell, vol. 46, no. 4, pp. 507-517, 2012.
5. S. S. C. Chim, T. K. F. Shing, E. C. W. Hung, et al., "Detection and characterization of placental microRNAs in maternal plasma, " Clinical Chemistry, vol. 54, no. 3, pp. 482-490, 2008.
6. C. H. Lawrie, S. Gal, H. M. Dunlop, et al., "Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma, " British Journal of Haematology, vol. 141, no. 5, pp. 672-675, 2008.
7. G. Reid, M. B. Kirschner, and N. van Zand wijk, "Circulating microRNAs: association with disease and potential use as biomarkers, " Critical Reviews in Oncology/Hematology, vol. 80, no. 2, pp. 193-208, 2011.
8. X. Chen, Y. Ba, L. Ma, et al., "Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases, " Cell Research, vol. 18, no. 10, pp. 997-1006, 2008.
9. N. B. Y. Tsui, E. K. O. Ng, and Y. M. D. Lo, "Stability of endogenous and added RNA in blood specimens, serum, and plasma, " Clinical Chemistry, vol. 48, no. 10, pp. 1647-1653, 2002.
10. M. P. Hunter, N. Ismail, X. Zhang, et al., "DetectionofmicroRNA expression in human peripheral blood microvesicles, " PLoS ONE, vol. 3, no. 11, Article ID e3694, 2008.
11. J. Skog, T. Wurdinger, S. van Rijn, et al., "Glioblastoma microvesicles transport RNAand proteins that promote tumour growth and provide diagnostic biomarkers, " Nature Cell Biology, vol. 10, no. 12, pp. 1470-1476, 2008.
12. H. Valadi, K. Ekstrom, A. Bossios, M. Sjostrand, J. J. Lee, and J. O. Lotvall, "Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells, " Nature Cell Biology, vol. 9, no. 6, pp. 654-659, 2007.
13. A. Zernecke, K. Bidzhekov, H. Noels, et al., "Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection, " Science Signaling, vol. 2, no. 100, p. ra81, 2009.
14. K. Wang, S. Zhang, J. Weber, D. Baxter, and D. J. Galas, "Export of microRNAs and microRNA-protective protein by mammalian cells, " Nucleic Acids Research, vol. 38, no. 20, pp. 7248-7259, 2010.
15. K. C. Vickers, B. T. Palmisano, B. M. Shoucri, R. D. Shamburek, and A. T. Remaley, "MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins, " Nature Cell Biology, vol. 13, no. 4, pp. 423-433, 2011.
16. A. Janowska-Wieczorek, M. Majka, J. Kijowski, et al., "Plateletderived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment, " Blood, vol. 98, no. 10, pp. 3143-3149, 2001.
17. O. Morel, F. Toti, B. Hugel, and J.-M. Freyssinet, "Cellular microparticles: a disseminated storage pool of bioactive vascular effectors, " Current Opinion in Hematology, vol. 11, no. 3, pp. 156-164, 2004.
18. E. E. Creemers, A. J. Tijsen, and Y. M. Pinto, "Circulating MicroRNAs: novel biomarkers and extracellular communicators in cardiovascular disease?" Circulation Research, vol. 110, no. 3, pp. 483-495, 2012.
19. S. Melo, H. Sugimoto, J. OConnell, et al., "Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis, " Cancer Cell, vol. 26, no. 5, pp. 707-721, 2014.
20. J. Xu, J. Zhao, G. Evan, C. Xiao, Y. Cheng, and J. Xiao, "Circulating microRNAs: novel biomarkers for cardiovascular diseases, " Journal of MolecularMedicine, vol. 90, no. 8, pp. 865-875, 2012.
21. E. M. Kroh, R. K. Parkin, P. S. Mitchell, and M. Tewari, "Analysis of circulating microRNA biomarkers in plasma and serum using quantitative reverse transcription-PCR (qRTPCR), " Methods, vol. 50, no. 4, pp. 298-301, 2010.
22. S. K. Gupta, C. Bang, and T. Thum, "Circulating microRNAs as biomarkers and potential paracrinemediators of cardiovascular disease, " Circulation: Cardiovascular Genetics, vol. 3, no. 5, pp. 484-488, 2010.
23. J.-N. Boeckel, C. E. Thome, D. Leistner, A. M. Zeiher, S. Fichtlscherer, and S. Dimmeler, "Heparin selectively affects the quantification of micrornas in human blood samples, " Clinical Chemistry, vol. 59, no. 7, pp. 1125-1127, 2013.
24. H. C. de Boer, C. van Solingen, J. Prins, et al., "Aspirin treatment hampers the use of plasma microRNA-126 as a biomarker for the progression of vascular disease, " European Heart Journal, vol. 34, no. 44, pp. 3451-3457, 2013.
25. J. S. Alpert, K. Thygesen, A. Jaffe, and H. D. White, "The universal definition of myocardial infarction: a consensus document: ischaemic heart disease, " Heart, vol. 94, no. 10, pp. 1335-1341, 2008.
26. B. Lauer, C. Niederau, U. Kuhl, et al., "Cardiac troponin T in patients with clinically suspected myocarditis, " Journal of the American College of Cardiology, vol. 30, no. 5, pp. 1354-1359, 1997.
27. S. Agewall, E. Giannitsis, T. Jernberg, and H. Katus, "Troponin elevation in coronary vs. non-coronary disease, " European Heart Journal, vol. 32, no. 4, pp. 404-411, 2011.
28. X. Ji, R. Takahashi, Y. Hiura, G. Hirokawa, Y. Fukushima, and N. Iwai, "Plasma miR-208 as a biomarker of myocardial injury, " Clinical Chemistry, vol. 55, no. 11, pp. 1944-1949, 2009.
29. G.-K. Wang, J.-Q. Zhu, J.-T. Zhang, et al., "Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans, " European Heart Journal, vol. 31, no. 6, pp. 659-666, 2010.
30. Y. DAlessand ra, P. Devanna, F. Limana, et al., "Circulating microRNAs are new and sensitive biomarkers of myocardial infarction, " European Heart Journal, vol. 31, no. 22, pp. 2765-2773, 2010.
31. S. Fichtlscherer, S. de Rosa, H. Fox, et al., "Circulating microRNAs in patients with coronary artery disease, " Circulation Research, vol. 107, no. 5, pp. 677-684, 2010.
32. J. Ai, R. Zhang, Y. Li, et al., "Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction, " Biochemical and Biophysical Research Communications, vol. 391, no. 1, pp. 73-77, 2010.
33. Y. Cheng, N. Tan, J. Yang, et al., "A translational study of circulating cell-free microRNA-1 in acute myocardial infarction, " Clinical Science, vol. 119, no. 2, pp. 87-95, 2010.
34. F. Wang, G. Long, C. Zhao, et al., "Plasma microRNA-133a is a new marker for both acute myocardial infarction and underlying coronary artery stenosis, " Journal of Translational Medicine, vol. 11, no. 1, article 222, 2013.
35. E. Bostjancic, N. Zidar, D. Stajer, and D. Glavac, "microRNA miR-1 is up-regulated in remote myocardium in patients with myocardial infarction, " Folia Biologica, vol. 56, no. 1, pp. 27-31, 2010.
36. J. Xiao, B. Shen, J. Li, et al., "Serum microRNA-499 and microRNA-208a as biomarkers of acute myocardial infarction, " International Journal of Clinical and ExperimentalMedicine, vol. 7, no. 1, pp. 136-141, 2014.
37. F. Olivieri, R. Antonicelli, L. Spazzafumo, et al., "Admission levels of circulating miR-499-5p and risk of death in elderly patients after acute non-ST elevation myocardial infarction, " International Journal of Cardiology, vol. 172, no. 2, pp. e276-e278, 2014.
38. F. He, P. Lv, X. Zhao, et al., "Predictive value of circulating miR and miR-134 for acute myocardial infarction, " Molecular and Cellular Biochemistry, 2014.
39. L. Peng, Q. Chun-guang, L. Bei-fang, et al., "Clinical impact of circulating miR-133, miR-1291 and miR-663b in plasma of patients with acute myocardial infarction, " Diagnostic Pathology, vol. 9, article 89, 2014.
40. C. Li, Z. Fang, T. Jiang, et al., "Serum microRNAs profile from genome-wide serves as a fingerprint for diagnosis of acutemyocardial infarction and angina pectoris, " BMCMedical Genomics, vol. 6, no. 1, article 16, 2013.
41. A. Zampetaki, P. Willeit, L. Tilling, et al., "Prospective study on circulating microRNAs and risk of myocardial infarction, " Journal of theAmerican College of Cardiology, vol. 60, no. 4, pp. 290-299, 2012.
42. C. Madamanchi, H. Alhosaini, A. Sumida, and M. S. Runge, "Obesity and natriuretic peptides, BNP and NT-proBNP: mechanisms and diagnostic implications for heart failure, " International Journal of Cardiology, vol. 176, no. 3, pp. 611-617, 2014.
43. A. J. Tijsen, E. E. Creemers, P. D. Moerland, et al., "MiR423-5p as a circulating biomarker for heart failure, " Circulation Research, vol. 106, no. 6, pp. 1035-1039, 2010.
44. Y. Goren, M. Kushnir, B. Zafrir, S. Tabak, B. S. Lewis, and O. Amir, "Serum levels of microRNAs in patients with heart failure, " European Journal ofHeart Failure, vol. 14, no. 2, pp. 147-154, 2012.
45. M. F. Corsten, R. Dennert, S. Jochems, et al., "Circulating MicroRNA-208b and MicroRNA-499 reflect myocardial damage in cardiovascular disease, " Circulation: Cardiovascular Genetics, vol. 3, no. 6, pp. 499-506, 2010.
46. Z. Liu, C. Zhou, Y. Liu, et al., "The expression levels of plasma micoRNAs in atrial fibrillation patients, " PLoS ONE, vol. 7, no. 9, Article ID e44906, 2012.
47. R. Roncarati, C. Viviani Anselmi, M. A. Losi, et al., "Circulating miR-29a, among other up-regulated microRNAs, is the only biomarker for both hypertrophy and fibrosis in patients with hypertrophic cardiomyopathy, " Journal of the American College of Cardiology, vol. 63, no. 9, pp. 920-927, 2014.
48. N. Nair, S. Kumar, E. Gongora, and S. Gupta, "Circulating miRNA as novel markers for diastolic dysfunction, " Molecular and Cellular Biochemistry, vol. 376, no. 1-2, pp. 33-40, 2013.
49. M. Jaguszewski, J. Osipova, J.-R. Ghadri, et al., "A signature of circulating microRNAs differentiates takotsubo cardiomyopathy from acute myocardial infarction, " European Heart Journal, vol. 35, no. 15, pp. 999-1006, 2014.
50. S. Li, J. Zhu, W. Zhang, et al., "Signature microRNA expression profile of essential hypertension and its novel link to human cytomegalovirus infection, " Circulation, vol. 124, no. 2, pp. 175-184, 2011.
51. Q. Yang, C. Jia, P. Wang, et al., "MicroRNA-505 identified from patients with essential hypertension impairs endothelial cell migration and tube formation, " International Journal of Cardiology, vol. 177, no. 3, pp. 925-934, 2014.
52. C. Wei, H. Henderson, C. Spradley, et al., "Circulating miRNAs as potential marker for pulmonary hypertension, " PLoS ONE, vol. 8, no. 5, Article IDe64396, 2013.
53. K. Schlosser, R. J. White, and D. J. Stewart, "MiR-26a linked to pulmonary hypertension by global assessment of circulating extracellular microRNAs, " American Journal of Respiratory and Critical Care Medicine, vol. 188, no. 12, pp. 1472-1475, 2013.
54. C. J. Rhodes, J. Wharton, R. A. Boon, et al., "Reducedmicrorna is associated with poor survival in pulmonary arterial hypertension, " American Journal of Respiratory and Critical Care Medicine, vol. 187, no. 3, pp. 294-302, 2013.
55. P. Libby, P. M. Ridker, and G. K. Hansson, "Progress and challenges in translating the biology of atherosclerosis, " Nature, vol. 473, no. 7347, pp. 317-325, 2011.
56. M. Hoekstra, C. A. C. van der Lans, B. Halvorsen, et al., "The peripheral blood mononuclear cell microRNA signature of coronary artery disease, " Biochemical and Biophysical Research Communications, vol. 394, no. 3, pp. 792-797, 2010.
57. C. Wu, Y. Gong, A. Sun, et al., "The humanMTHFR rs4846049 polymorphism increases coronary heart disease risk through modifying miRNA binding, " Nutrition, Metabolismand Cardiovascular Diseases, vol. 23, no. 7, pp. 693-698, 2013.
58. J. Wang, C.-H. Yan, Y. Li, et al., "MicroRNA-31 controls phenotypic modulation of human vascular smooth muscle cells by regulating its target gene cellular repressor of E1A-stimulated genes, " Experimental Cell Research, vol. 319, no. 8, pp. 1165-1175, 2013.
59. H. Q. Lu, C. Liang, Z. Q. He, M. Fan, and Z. G. Wu, "Circulating miR-214 is associated with the severity of coronary artery disease, " Journal of Geriatric Cardiology, vol. 10, no. 1, pp. 34-38, 2013.
60. W. Gao, H.-W. He, Z.-M. Wang, et al., "Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease, " Lipids in Health and Disease, vol. 11, article 55, 2012.
61. W. Hacke, M. Kaste, E. Bluhmki, et al., "Thrombolysis with alteplase 3 to 4. 5 hours after acute ischemic stroke, " The New England Journal ofMedicine, vol. 359, no. 13, pp. 1317-1329, 2008.
62. O. F. Laterza, L. Lim, P. W. Garrett-Engele, et al., "Plasma microRNAs as sensitive and specific biomarkers of tissue injury, " Clinical Chemistry, vol. 55, no. 11, pp. 1977-1983, 2009.
63. H. Weng, C. Shen, G. Hirokawa, et al., "Plasma miR-124 as a biomarker for cerebral infarction, " Biomedical Research, vol. 32, no. 2, pp. 135-141, 2011.
64. S. Sepramaniam, J.-R. Tan, K.-S. Tan, et al., "Circulating microRNAs as biomarkers of acute stroke, " International Journal of Molecular Sciences, vol. 15, no. 1, pp. 1418-1432, 2014.
65. K. Jeyaseelan, K. Y. Lim, and A. Armugam, "MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion, " Stroke, vol. 39, no. 3, pp. 959-966, 2008.
66. D.-Z. Liu, Y. Tian, B. P. Ander, et al., "Brainand bloodmicroRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures, " Journal of Cerebral Blood Flowand Metabolism, vol. 30, no. 1, pp. 92-101, 2010.
67. W. H. Wang, S. Guan, L. Y. Zhang, S. Lei, and Y. J. Zeng, "Circulating microRNAs as novel potential biomarkers for early diagnosis of acute stroke in humans, " Journal of Stroke and Cerebrovascular Diseases, vol. 23, no. 10, pp. 2607-2613, 2014.
68. Y. P. Liu, J. J. Zhang, R. F. Han, H. X. Liu, D. Sun, and X. Liu, "Downregulation of serum brain specific microRNA is associated with inflammation and infarct volume in acute ischemic stroke, " Journal of Clinical Neuroscience, vol. 22, no. 2, pp. 291-295, 2015.
69. G. Long, F. Wang, H. Li, et al., "Circulating miR-30a, miR-126 and let-7b as biomarker for ischemic stroke in humans, " BMC Neurology, vol. 13, article 178, 2013.
70. G. C. Jickling, B. P. Ander, X. Zhan, et al., "microRNAexpression in peripheral blood cells following acute ischemic stroke and their predicted gene targets, " PLoS ONE, vol. 9, no. 6, Article ID e99283, 2014.
71. L. Zeng, J. Liu, Y. Wang, et al., "MicroRNA-210 as a novel blood biomarker in acute cerebral ischemia, " Frontiers in Bioscience: Elite, vol. 3, no. 4, pp. 1265-1272, 2011.
72. S. Eminaga, D. C. Christodoulou, F. Vigneault, G. M. Church, and J. G. Seidman, "UNIT 4. 17 quantification of microRNA expression with next-generation sequencing, " Current Protocols in Molecular Biology, 2013.