The variable chemotherapeutic response of Malabaricone-A in leukemic and solid tumor cell lines depends on the degree of redox imbalance

Phytomedicine

Volumn 22, Issue 7-8, 2015, Pages 713-723

  Manna, Alak ^a   De Sarkar, Sritama ^a   De, Soumita ^a   Bauri, Ajay K ^b   Chattopadhyay, Subrata ^b   Chatterjee, Mitali ^a  

^a INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

^b BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Apoptosis; Malabaricone A; Oxidative stress; Pro oxidant; Reactive oxygen species; Redox imbalance

Indexed keywords

5 CHLOROMETHYLFLUORESCEIN DIACETATE; ACETOACETIC ACID; ACETYLCYSTEINE; ACRIDINE ORANGE; BUTHIONINE SULFOXIMINE; CARDIOLIPIN; CASPASE 3; CATALASE; CYTOTOXIC AGENT; DICHLOROFLUORESCEIN; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HEME OXYGENASE 1; MALABARICONE A; PROPIDIUM IODIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; RESORCINOL DERIVATIVE;

A549 CELL LINE; APOPTOSIS; ARTICLE; CALCEIN-AM ASSAY; CELL CYCLE PROGRESSION; CELL VIABILITY ASSAY; CYTOTOXICITY; DRUG EFFICACY; DRUG SCREENING; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE; HEPG2 CELL LINE; HL 60 CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; K562 CELL LINE; LEUKEMIA CELL LINE; MCF 7 CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLT3 CELL LINE; OXIDATION REDUCTION REACTION; PEROXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPECTROPHOTOMETRY; TUMOR CELL LINE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; METABOLISM; MYRISTICACEAE;

MYRISTICA MALABARICA;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; HEP G2 CELLS; HL-60 CELLS; HUMANS; K562 CELLS; MCF-7 CELLS; MYRISTICACEAE; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; RESORCINOLS;

EID: 84935880922     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2015.05.007     Document Type: Article

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