Caspase-1 inhibitor ameliorates experimental autoimmune myasthenia gravis by innate dendric cell IL-1-IL-17 pathway

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Wang, Cong Cong ^a   Li, Heng ^a   Zhang, Min ^a   Li, Xiao Li ^a   Yue, Long Tao ^a   Zhang, Peng ^a   Zhao, Yue ^a   Wang, Shan ^a   Duan, Ruo Nan ^a   Li, Yan Bin ^a   Duan, Rui Sheng ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Caspase 1 inhibitor; Dendric cell; Experimental autoimmune myasthenia gravis; Follicular helper T cell; IL 1 ; Th17 cell

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; AUTOANTIBODY; CASPASE INHIBITOR; CHOLINERGIC RECEPTOR; CYTOKINE; ENZYME INHIBITOR; INTERLEUKIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS; FEMALE; GAMMA DELTA T LYMPHOCYTE; HELPER CELL; INNATE IMMUNITY; MYASTHENIA GRAVIS; NEUROPROTECTION; NONHUMAN; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; IMMUNOLOGY; LEWIS RAT; LYMPHOCYTE; MONOCYTE; MYASTHENIA GRAVIS, AUTOIMMUNE, EXPERIMENTAL; PATHOLOGY;

ANIMALS; AUTOANTIBODIES; CASPASE 1; CASPASE INHIBITORS; CYTOKINES; DENDRITIC CELLS; ENZYME INHIBITORS; FEMALE; INTERLEUKIN-1; INTERLEUKIN-17; LYMPHOCYTES; MONOCYTES; MYASTHENIA GRAVIS, AUTOIMMUNE, EXPERIMENTAL; RATS; RATS, INBRED LEW; RECEPTORS, CHOLINERGIC; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 84935837696     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0334-4     Document Type: Article

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