Embryonic GABAB receptor blockade alters cell migration, adult hypothalamic structure, and anxiety- and depression-like behaviors sex specifically in mice

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Stratton, Matthew S ^a   Staros, Michelle ^a   Budefeld, Tomaz ^b   Searcy, Brian T ^a   Nash, Connor ^a   Eitel, Chad ^a   Carbone, David ^c   Handa, Robert J ^c   Majdic, Gregor ^b   Tobet, Stuart A ^a,d  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^d Department of Mechanical Engineering   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; 2-HYDROXYSACLOFEN; 4 AMINOBUTYRIC ACID; BACLOFEN; PHOSPHINIC ACID DERIVATIVE; PROPANOLAMINE DERIVATIVE; PROTEIN SUBUNIT;

ADULT; ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; CELL MIGRATION; CELL MOTION; CONTROLLED STUDY; DEPRESSION; EMBRYO DEVELOPMENT; FEMALE; FETUS; FETUS DEVELOPMENT; HYPERACTIVITY; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IN VIVO STUDY; MALE; MORPHOLOGY; MOUSE; NONHUMAN; SEX DIFFERENCE; SIGNAL TRANSDUCTION; STRESS; ANALOGS AND DERIVATIVES; ANIMAL; ANIMAL EMBRYO; CHEMICALLY INDUCED; DEFICIENCY; DRUG EFFECTS; EMBRYOLOGY; GENE EXPRESSION; GENETICS; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; IMMOBILIZATION; MAZE TEST; MENTAL STRESS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PREGNANCY; PROTEIN SUBUNIT; RESTLESSNESS; TISSUE CULTURE TECHNIQUE; TRANSGENIC MOUSE;

ANIMALS; ANXIETY; BACLOFEN; CELL MOVEMENT; DEPRESSION; EMBRYO, MAMMALIAN; FEMALE; GABA-B RECEPTOR ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMOBILIZATION; MALE; MAZE LEARNING; MICE; MICE, TRANSGENIC; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PHOSPHINIC ACIDS; PITUITARY-ADRENAL SYSTEM; PREGNANCY; PROPANOLAMINES; PROTEIN SUBUNITS; PSYCHOMOTOR AGITATION; RECEPTORS, GABA-B; SEX FACTORS; STRESS, PSYCHOLOGICAL; TISSUE CULTURE TECHNIQUES;

EID: 84935738991     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106015     Document Type: Article

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