Prepro-thyrotropin releasing hormone expressing neurons in the juxtaparaventricular region of the lateral hypothalamus are activated by leptin and altered by prenatal glucocorticoid exposure

Brain Research

Volumn 1477, Issue , 2012, Pages 19-26

  Carbone, David L ^a   Zuloaga, Damian G ^a   Lacagnina, Anthony F ^a   Handa, Robert J ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Dexamethasone; Energy balance; Hyperphagia; Juxtaparaventricular region of the lateral hypothalamus; Thyrotropin releasing hormone

Indexed keywords

DEXAMETHASONE; LEPTIN; PROTIRELIN;

ANIMAL EXPERIMENT; ARTICLE; BIRTH WEIGHT; BODY WEIGHT; BRAIN FORNIX; CENTRAL NERVOUS SYSTEM; ENERGY BALANCE; FEMALE; FETUS; FETUS DEVELOPMENT; FOOD INTAKE; GESTATIONAL AGE; LATERAL HYPOTHALAMUS; MALE; NERVE CELL; NONHUMAN; PARAVENTRICULAR THALAMIC NUCLEUS; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SATIETY; WEIGHT GAIN; WEIGHT REDUCTION;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; DEXAMETHASONE; EATING; FEMALE; GLUCOCORTICOIDS; HYPOTHALAMUS; LEPTIN; MALE; NEURONS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROTEIN PRECURSORS; RATS; SEX FACTORS; THYROTROPIN-RELEASING HORMONE;

RATTUS;

EID: 84866370295     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.08.020     Document Type: Article

References (24)

1. M. Abercrombie Estimation of nuclear population from microtome sections Anat. Rec. 94 1946 239 247
2. D.L. Carbone, D.G. Zuloaga, R. Hiroi, C.D. Foradori, M.E. Legare, and R.J. Handa Prenatal dexamethasone exposure potentiates diet-induced hepatosteatosis and decreases plasma IGF-I in a sex-specific fashion Endocrinology 153 2012 295 306
3. Carbone, D.L., Zuloaga, D.G., Lacagnina, A.F., McGivern, R.F., Handa, R.J. Exposure to dexamethasone during late gestation causes female-specific decreases in core body temperature and prepro-thyrotropin-releasing hormone expression in the paraventricular nucleus of the hypothalamus in rats. Physiology and Behavior, 10.1016/j.physbeh.2012.07.010, in press.
4. Y.H. Choi, D. Hartzell, M.J. Azain, and C.A. Baile TRH decreases food intake and increases water intake and body temperature in rats Physiol. Behav. 77 2002 1 4 (Pubitemid 35245713)
5. M.E. Cleasby, P.A. Kelly, B.R. Walker, and J.R. Seckl Programming of rat muscle and fat metabolism by in utero overexposure to glucocorticoids Endocrinology 144 2003 999 1007 (Pubitemid 36262867)
6. R.E. Coggeshall, and H.A. Lekan Methods for determining numbers of cells and synapses: a case for more uniform standards of review J. Comp. Neurol. 364 1996 6 15 (Pubitemid 26026631)
7. A.J. Drake, P.J. Raubenheimer, D. Kerrigan, K.J. McInnes, J.R. Seckl, and B.R. Walker Prenatal dexamethasone programs expression of genes in liver and adipose tissue and increased hepatic lipid accumulation but not obesity on a high-fat diet Endocrinology 151 2010 1581 1587
8. F. Duksal, I. Kilic, A.C. Tufan, and I. Akdogan Effects of different corticosteroids on the brain weight and hippocampal neuronal loss in rats Brain Res. 1250 2009 75 80
9. J.D. Hahn, and L.W. Swanson Distinct patterns of neuronal inputs and outputs of the juxtaparaventricular and suprafornical regions of the lateral hypothalamic area in the male rat Brain Res. Rev. 64 2010 14 103
10. H. Heuer, M.K. Schafer, D. O'Donnell, P. Walker, and K. Bauer Expression of thyrotropin-releasing hormone receptor 2 (TRH-R2) in the central nervous system of rats J. Comp. Neurol. 428 2000 319 336
11. M.L. Kreider, C.A. Tate, M.M. Cousins, C.A. Oliver, F.J. Seidler, and T.A. Slotkin Lasting effects of developmental dexamethasone treatment on neural cell number and size, synaptic activity, and cell signaling: critical periods of vulnerability, dose-effect relationships, regional targets, and sex selectivity Neuropsychopharmacology 31 2006 12 35 (Pubitemid 43250938)
12. R.M. Lechan, and C. Fekete The TRH neuron: a hypothalamic integrator of energy metabolism Prog. Brain Res. 153 2006 209 235 (Pubitemid 44107417)
13. R.M. Luque, and R.D. Kineman Gender-dependent role of endogenous somatostatin in regulating growth hormone-axis function in mice Endocrinology 148 2007 5998 6006 (Pubitemid 350146151)
14. I. Merchenthaler Co-localization of enkephalin and TRH in perifornical neurons of the rat hypothalamus that project to the lateral septum Brain Res. 544 1991 177 180
15. D.E. Pankevich, B.R. Mueller, B. Brockel, and T.L. Bale Prenatal stress programming of offspring feeding behavior and energy balance begins early in pregnancy Physiol. Behav. 98 2009 94 102
16. S. Schuhler, A. Warner, N. Finney, G.W. Bennett, F.J. Ebling, and J.M. Brameld Thyrotrophin-releasing hormone decreases feeding and increases body temperature, activity and oxygen consumption in Siberian hamsters J. Neuroendocrinol. 19 2007 239 249 (Pubitemid 46372126)
17. M.M. Scott, J.L. Lachey, S.M. Sternson, C.E. Lee, C.F. Elias, J.M. Friedman, and J.K. Elmquist Leptin targets in the mouse brain J. Comp. Neurol. 514 2009 518 532
18. T.P. Segerson, J. Kauer, H.C. Wolfe, H. Mobtaker, P. Wu, I.M. Jackson, and R.M. Lechan Thyroid hormone regulates TRH biosynthesis in the paraventricular nucleus of the rat hypothalamus Science 238 1987 78 80 (Pubitemid 17150486)
19. T. Sharp, G.W. Bennett, C.A. Marsden, and I.F. Tulloch A comparison of the locomotor effects induced by centrally injected TRH and TRH analogues Regul. Pept. 9 1984 305 315 (Pubitemid 15191266)
20. S. Suzuki, L.C. Solberg, E.E. Redei, and R.J. Handa Prepro-thyrotropin releasing hormone 178-199 immunoreactivity is altered in the hypothalamus of the Wistar-Kyoto strain of rat Brain Res. 913 2001 224 233 (Pubitemid 32817071)
21. T. Suzuki, H. Kohno, T. Sakurada, T. Tadano, and K. Kisara Intracranial injection of thyrotropin releasing hormone (TRH) suppresses starvation-induced feeding and drinking in rats Pharmacol. Biochem. Behav. 17 1982 249 253 (Pubitemid 12020794)
22. K.L. Watterberg Policy statement - postnatal corticosteroids to prevent or treat bronchopulmonary dysplasia Pediatrics 126 2010 800 808
23. G. Wittmann, T. Fuzesi, Z. Liposits, R.M. Lechan, and C. Fekete Distribution and axonal projections of neurons coexpressing thyrotropin- releasing hormone and urocortin 3 in the rat brain J. Comp. Neurol. 517 2009 825 840
24. G. Wittmann, T. Fuzesi, P.S. Singru, Z. Liposits, R.M. Lechan, and C. Fekete Efferent projections of thyrotropin-releasing hormone-synthesizing neurons residing in the anterior parvocellular subdivision of the hypothalamic paraventricular nucleus J. Comp. Neurol. 515 2009 313 330