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Volumn 45, Issue 7, 2015, Pages 2008-2016

Liver sinusoidal endothelial cells induce immunosuppressive IL-10-producing Th1 cells via the Notch pathway

Author keywords

Hepatic immune tolerance; IL 10; Liver sinusoidal endothelial cells; Modulation of Th1 cells; Notch pathway

Indexed keywords

INTERLEUKIN 10; NOTCH RECEPTOR; IL10 PROTEIN, MOUSE;

EID: 84935703584     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201445346     Document Type: Article
Times cited : (49)

References (32)
  • 2
    • 18244364834 scopus 로고    scopus 로고
    • Development and functional consequences of LPS tolerance in sinusoidal endothelial cells of the liver
    • Uhrig, A., Banafsche, R., Kremer, M., Hegenbarth, S., Hamann, A., Neurath, M., Gerken, G. et al., Development and functional consequences of LPS tolerance in sinusoidal endothelial cells of the liver. J. Leukoc. Biol. 2005. 77: 626-633.
    • (2005) J. Leukoc. Biol. , vol.77 , pp. 626-633
    • Uhrig, A.1    Banafsche, R.2    Kremer, M.3    Hegenbarth, S.4    Hamann, A.5    Neurath, M.6    Gerken, G.7
  • 3
    • 84886646838 scopus 로고    scopus 로고
    • Immune surveillance by the liver
    • Jenne, C. N. and Kubes, P., Immune surveillance by the liver. Nat. Immunol. 2013. 14: 996-1006.
    • (2013) Nat. Immunol. , vol.14 , pp. 996-1006
    • Jenne, C.N.1    Kubes, P.2
  • 4
    • 38649137987 scopus 로고    scopus 로고
    • Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance
    • Diehl, L., Schurich, A., Grochtmann, R., Hegenbarth, S., Chen, L. and Knolle, P. A., Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance. Hepatology 2008. 47: 296-305.
    • (2008) Hepatology , vol.47 , pp. 296-305
    • Diehl, L.1    Schurich, A.2    Grochtmann, R.3    Hegenbarth, S.4    Chen, L.5    Knolle, P.A.6
  • 5
    • 0034533209 scopus 로고    scopus 로고
    • Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance
    • Limmer, A., Ohl, J., Kurts, C., Ljunggren, H. G., Reiss, Y., Groettrup, M., Momburg, F. et al., Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance. Nat. Med. 2000. 6: 1348-1354.
    • (2000) Nat. Med. , vol.6 , pp. 1348-1354
    • Limmer, A.1    Ohl, J.2    Kurts, C.3    Ljunggren, H.G.4    Reiss, Y.5    Groettrup, M.6    Momburg, F.7
  • 6
    • 84906319860 scopus 로고    scopus 로고
    • TGF-beta-dependent induction of CD4+CD25+Foxp3+ Tregs by liver sinusoidal endothelial cells
    • Carambia, A., Freund, B., Schwinge, D., Heine, M., Laschtowitz, A., Huber, S., Wraith, D. C. et al., TGF-beta-dependent induction of CD4+CD25+Foxp3+ Tregs by liver sinusoidal endothelial cells. J. Hepatol. 2014. 61: 594-599.
    • (2014) J. Hepatol. , vol.61 , pp. 594-599
    • Carambia, A.1    Freund, B.2    Schwinge, D.3    Heine, M.4    Laschtowitz, A.5    Huber, S.6    Wraith, D.C.7
  • 7
    • 73149098744 scopus 로고    scopus 로고
    • Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3- regulatory T cells suppressing autoimmune hepatitis
    • Kruse, N., Neumann, K., Schrage, A., Derkow, K., Schott, E., Erben, U., Kuhl, A. et al., Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3- regulatory T cells suppressing autoimmune hepatitis. Hepatology 2009. 50: 1904-1913.
    • (2009) Hepatology , vol.50 , pp. 1904-1913
    • Kruse, N.1    Neumann, K.2    Schrage, A.3    Derkow, K.4    Schott, E.5    Erben, U.6    Kuhl, A.7
  • 8
    • 33847163271 scopus 로고    scopus 로고
    • CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis
    • Anderson, C. F., Oukka, M., Kuchroo, V. J. and Sacks, D., CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J. Exp. Med. 2007. 204: 285-297.
    • (2007) J. Exp. Med. , vol.204 , pp. 285-297
    • Anderson, C.F.1    Oukka, M.2    Kuchroo, V.J.3    Sacks, D.4
  • 9
    • 33847144180 scopus 로고    scopus 로고
    • Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection
    • Jankovic, D., Kullberg, M. C., Feng, C. G., Goldszmid, R. S., Collazo, C. M., Wilson, M., Wynn, T. A. et al., Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. J. Exp. Med. 2007. 204: 273-283.
    • (2007) J. Exp. Med. , vol.204 , pp. 273-283
    • Jankovic, D.1    Kullberg, M.C.2    Feng, C.G.3    Goldszmid, R.S.4    Collazo, C.M.5    Wilson, M.6    Wynn, T.A.7
  • 10
    • 62049085168 scopus 로고    scopus 로고
    • Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10
    • Sun, J., Madan, R., Karp, C. L. and Braciale, T. J., Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10. Nat. Med. 2009. 15: 277-284.
    • (2009) Nat. Med. , vol.15 , pp. 277-284
    • Sun, J.1    Madan, R.2    Karp, C.L.3    Braciale, T.J.4
  • 12
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: a simple pathway becomes complex
    • Bray, S. J., Notch signalling: a simple pathway becomes complex. Nat. Rev. Mol. Cell. Biol. 2006. 7: 678-689.
    • (2006) Nat. Rev. Mol. Cell. Biol. , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 13
    • 84878233150 scopus 로고    scopus 로고
    • Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection
    • Huang, L. R., Wohlleber, D., Reisinger, F., Jenne, C. N., Cheng, R. L., Abdullah, Z., Schildberg, F. A. et al., Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. Nat. Immunol. 2013. 14: 574-583.
    • (2013) Nat. Immunol. , vol.14 , pp. 574-583
    • Huang, L.R.1    Wohlleber, D.2    Reisinger, F.3    Jenne, C.N.4    Cheng, R.L.5    Abdullah, Z.6    Schildberg, F.A.7
  • 14
    • 0032841846 scopus 로고    scopus 로고
    • Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence
    • Cerny, A. and Chisari, F. V., Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence. Hepatology 1999. 30: 595-601.
    • (1999) Hepatology , vol.30 , pp. 595-601
    • Cerny, A.1    Chisari, F.V.2
  • 15
    • 36248970702 scopus 로고    scopus 로고
    • Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
    • Fitzgerald, D. C., Zhang, G. X., El-Behi, M., Fonseca-Kelly, Z., Li, H., Yu, S., Saris, C. J. et al., Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat. Immunol. 2007. 8: 1372-1379.
    • (2007) Nat. Immunol. , vol.8 , pp. 1372-1379
    • Fitzgerald, D.C.1    Zhang, G.X.2    El-Behi, M.3    Fonseca-Kelly, Z.4    Li, H.5    Yu, S.6    Saris, C.J.7
  • 16
    • 84856567798 scopus 로고    scopus 로고
    • IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection
    • Freitas do Rosario, A. P., Lamb, T., Spence, P., Stephens, R., Lang, A., Roers, A., Muller, W. et al., IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. J. Immunol. 2012. 188: 1178-1190.
    • (2012) J. Immunol. , vol.188 , pp. 1178-1190
    • Freitas do Rosario, A.P.1    Lamb, T.2    Spence, P.3    Stephens, R.4    Lang, A.5    Roers, A.6    Muller, W.7
  • 17
    • 33846438598 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand
    • Ito, T., Yang, M., Wang, Y. H., Lande, R., Gregorio, J., Perng, O. A., Qin, X. F. et al., Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand. J. Exp. Med. 2007. 204: 105-115.
    • (2007) J. Exp. Med. , vol.204 , pp. 105-115
    • Ito, T.1    Yang, M.2    Wang, Y.H.3    Lande, R.4    Gregorio, J.5    Perng, O.A.6    Qin, X.F.7
  • 18
    • 0036740602 scopus 로고    scopus 로고
    • ICOS and CD28 reversely regulate IL-10 on re-activation of human effector T cells with mature dendritic cells
    • Witsch, E. J., Peiser, M., Hutloff, A., Buchner, K., Dorner, B. G., Jonuleit, H., Mages, H. W. et al., ICOS and CD28 reversely regulate IL-10 on re-activation of human effector T cells with mature dendritic cells. Eur. J. Immunol. 2002. 32: 2680-2686.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2680-2686
    • Witsch, E.J.1    Peiser, M.2    Hutloff, A.3    Buchner, K.4    Dorner, B.G.5    Jonuleit, H.6    Mages, H.W.7
  • 20
    • 76249101454 scopus 로고    scopus 로고
    • Cutting edge: plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis
    • Kassner, N., Krueger, M., Yagita, H., Dzionek, A., Hutloff, A., Kroczek, R., Scheffold, A. et al., Cutting edge: plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis. J. Immunol. 2010. 184: 550-554.
    • (2010) J. Immunol. , vol.184 , pp. 550-554
    • Kassner, N.1    Krueger, M.2    Yagita, H.3    Dzionek, A.4    Hutloff, A.5    Kroczek, R.6    Scheffold, A.7
  • 22
    • 34447634411 scopus 로고    scopus 로고
    • Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch
    • Amsen, D., Antov, A., Jankovic, D., Sher, A., Radtke, F., Souabni, A., Busslinger, M. et al., Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 2007. 27: 89-99.
    • (2007) Immunity , vol.27 , pp. 89-99
    • Amsen, D.1    Antov, A.2    Jankovic, D.3    Sher, A.4    Radtke, F.5    Souabni, A.6    Busslinger, M.7
  • 25
    • 84888374898 scopus 로고    scopus 로고
    • Hepatocytes contribute to immune regulation in the liver by activation of the Notch signaling pathway in T cells
    • Burghardt, S., Erhardt, A., Claass, B., Huber, S., Adler, G., Jacobs, T., Chalaris, A. et al., Hepatocytes contribute to immune regulation in the liver by activation of the Notch signaling pathway in T cells. J. Immunol. 2013. 191: 5574-5582.
    • (2013) J. Immunol. , vol.191 , pp. 5574-5582
    • Burghardt, S.1    Erhardt, A.2    Claass, B.3    Huber, S.4    Adler, G.5    Jacobs, T.6    Chalaris, A.7
  • 26
    • 84871247127 scopus 로고    scopus 로고
    • Inhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cells
    • Carambia, A., Frenzel, C., Bruns, O. T., Schwinge, D., Reimer, R., Hohenberg, H., Huber, S. et al., Inhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cells. J. Hepatol. 2013. 58: 112-118.
    • (2013) J. Hepatol. , vol.58 , pp. 112-118
    • Carambia, A.1    Frenzel, C.2    Bruns, O.T.3    Schwinge, D.4    Reimer, R.5    Hohenberg, H.6    Huber, S.7
  • 27
    • 0033002962 scopus 로고    scopus 로고
    • Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells
    • Knolle, P. A., Schmitt, E., Jin, S., Germann, T., Duchmann, R., Hegenbarth, S., Gerken, G. et al., Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells. Gastroenterology 1999. 116: 1428-1440.
    • (1999) Gastroenterology , vol.116 , pp. 1428-1440
    • Knolle, P.A.1    Schmitt, E.2    Jin, S.3    Germann, T.4    Duchmann, R.5    Hegenbarth, S.6    Gerken, G.7
  • 28
    • 33845899370 scopus 로고    scopus 로고
    • Role of Kupffer cells in the pathogenesis of liver disease
    • Kolios, G., Valatas, V. and Kouroumalis, E., Role of Kupffer cells in the pathogenesis of liver disease. World J. Gastroenterol. 2006. 12: 7413-7420.
    • (2006) World J. Gastroenterol. , vol.12 , pp. 7413-7420
    • Kolios, G.1    Valatas, V.2    Kouroumalis, E.3
  • 29
    • 0034070797 scopus 로고    scopus 로고
    • The liver as a crucial organ in the first line of host defense: the roles of Kupffer cells, natural killer (NK) cells and NK1.1 Ag+ T cells in T helper 1 immune responses
    • Seki, S., Habu, Y., Kawamura, T., Takeda, K., Dobashi, H., Ohkawa, T. and Hiraide, H., The liver as a crucial organ in the first line of host defense: the roles of Kupffer cells, natural killer (NK) cells and NK1.1 Ag+ T cells in T helper 1 immune responses. Immunol. Rev. 2000. 174: 35-46.
    • (2000) Immunol. Rev. , vol.174 , pp. 35-46
    • Seki, S.1    Habu, Y.2    Kawamura, T.3    Takeda, K.4    Dobashi, H.5    Ohkawa, T.6    Hiraide, H.7
  • 30
    • 1842480002 scopus 로고    scopus 로고
    • Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration
    • Kohler, C., Bell, A. W., Bowen, W. C., Monga, S. P., Fleig, W. and Michalopoulos, G. K., Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration. Hepatology 2004. 39: 1056-1065.
    • (2004) Hepatology , vol.39 , pp. 1056-1065
    • Kohler, C.1    Bell, A.W.2    Bowen, W.C.3    Monga, S.P.4    Fleig, W.5    Michalopoulos, G.K.6
  • 32
    • 84861562120 scopus 로고    scopus 로고
    • Connecting liver and gut: murine liver sinusoidal endothelium induces gut tropism of CD4+ T cells via retinoic acid
    • Neumann, K., Kruse, N., Szilagyi, B., Erben, U., Rudolph, C., Flach, A., Zeitz, M. et al., Connecting liver and gut: murine liver sinusoidal endothelium induces gut tropism of CD4+ T cells via retinoic acid. Hepatology 2012. 55: 1976-1984.
    • (2012) Hepatology , vol.55 , pp. 1976-1984
    • Neumann, K.1    Kruse, N.2    Szilagyi, B.3    Erben, U.4    Rudolph, C.5    Flach, A.6    Zeitz, M.7


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