메뉴 건너뛰기




Volumn 60, Issue 5, 2015, Pages 703-712

Pseudomonas aeruginosa in cystic fibrosis patients with G551D-CFTR treated with ivacaftor

Author keywords

CFTR modulator; Cystic fibrosis; Ivacaftor; P. aeruginosa

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; IVACAFTOR; AMINOPHENOL DERIVATIVE; ENZYME ACTIVATOR; MUTANT PROTEIN; QUINOLONE DERIVATIVE;

EID: 84935511737     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciu944     Document Type: Article
Times cited : (195)

References (47)
  • 2
    • 78549279173 scopus 로고    scopus 로고
    • Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation
    • Accurso FJ, Rowe SM, Clancy JP, et al. Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation. N Engl J Med 2010; 363:1991-2003.
    • (2010) N Engl J Med , vol.363 , pp. 1991-2003
    • Accurso, F.J.1    Rowe, S.M.2    Clancy, J.P.3
  • 3
    • 78651131843 scopus 로고
    • Sweat tests for diagnosis of cystic fibrosis
    • Gibbs GE. Sweat tests for diagnosis of cystic fibrosis. Q Rev Pediatr 1958; 13:188-91.
    • (1958) Q Rev Pediatr , vol.13 , pp. 188-191
    • Gibbs, G.E.1
  • 4
    • 80455162465 scopus 로고    scopus 로고
    • A CFTR potentiator in patients with cystic fibrosis and the G551D mutation
    • Ramsey BW, Davies J, McElvaney NG, et al. A CFTR potentiator in patients with cystic fibrosis and the G551D mutation. N Engl J Med 2011; 365:1663-72.
    • (2011) N Engl J Med , vol.365 , pp. 1663-1672
    • Ramsey, B.W.1    Davies, J.2    McElvaney, N.G.3
  • 5
    • 0025355607 scopus 로고
    • Pulmonary function and clinical course in patients with cystic fibrosis after pulmonary colonization with Pseudomonas aeruginosa
    • Kerem E, CoreyM, Gold R, Levison H. Pulmonary function and clinical course in patients with cystic fibrosis after pulmonary colonization with Pseudomonas aeruginosa. J Pediatr 1990; 116:714-9.
    • (1990) J Pediatr , vol.116 , pp. 714-719
    • Kerem, E.1    Coreym2    Gold, R.3    Levison, H.4
  • 6
    • 0029177535 scopus 로고
    • Effects of Pseudomonas aeruginosa colonization on lung function and anthropometric variables in children with cystic fibrosis
    • Pamukcu A, Bush A, Buchdahl R. Effects of Pseudomonas aeruginosa colonization on lung function and anthropometric variables in children with cystic fibrosis. Pediatr Pulmonol 1995; 19:10-5.
    • (1995) Pediatr Pulmonol , vol.19 , pp. 10-15
    • Pamukcu, A.1    Bush, A.2    Buchdahl, R.3
  • 7
    • 0034785481 scopus 로고    scopus 로고
    • Acceleration of lung disease in children with cystic fibrosis after pseudomonas aeruginosa acquisition
    • Kosorok MR, Zeng L, West SE, et al. Acceleration of lung disease in children with cystic fibrosis after Pseudomonas aeruginosa acquisition. Pediatr Pulmonol 2001; 32:277-87.
    • (2001) Pediatr Pulmonol , vol.32 , pp. 277-287
    • Kosorok, M.R.1    Zeng, L.2    West, S.E.3
  • 8
    • 0026831341 scopus 로고
    • Mucoid Pseudomonas aeruginosa is a marker of poor survival in cystic fibrosis
    • Henry RL, Mellis CM, Petrovic L. Mucoid Pseudomonas aeruginosa is a marker of poor survival in cystic fibrosis. Pediatr Pulmonol 1992; 12:158-61.
    • (1992) Pediatr Pulmonol , vol.12 , pp. 158-161
    • Henry, R.L.1    Mellis, C.M.2    Petrovic, L.3
  • 9
    • 84906952377 scopus 로고    scopus 로고
    • Clinical mechanism of the CFTR potentiator ivacaftor in G551D-mediated cystic fibrosis
    • Rowe SM, Heltshe SL, Gonska T, et al. Clinical mechanism of the CFTR potentiator ivacaftor in G551D-mediated cystic fibrosis. Am J Respir Crit Care Med 2014; 190:175-84.
    • (2014) Am J Respir Crit Care Med , vol.190 , pp. 175-184
    • Rowe, S.M.1    Heltshe, S.L.2    Gonska, T.3
  • 11
    • 36248953255 scopus 로고    scopus 로고
    • Cystic fibrosis pulmonary guidelines: Chronic medications for maintenance of lung health
    • Flume PA, O'Sullivan BP, Robinson KA, et al. Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health. Am J Respir Crit Care Med 2007; 176:957-69.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 957-969
    • Flume, P.A.1    O'sullivan, B.P.2    Robinson, K.A.3
  • 12
    • 0037505909 scopus 로고    scopus 로고
    • Infection control recommendations for patients with cystic fibrosis: Microbiology, important pathogens, and infection control practices to prevent patient-to-patient transmission
    • Saiman L, Siegel J. Infection control recommendations for patients with cystic fibrosis: microbiology, important pathogens, and infection control practices to prevent patient-to-patient transmission. Infect Control Hosp Epidemiol 2003; 24(5 suppl):S6-52.
    • (2003) Infect Control Hosp Epidemiol , vol.24 , pp. S6-52
    • Saiman, L.1    Siegel, J.2
  • 13
    • 0038102859 scopus 로고    scopus 로고
    • Evaluation of a new definition for chronic Pseudomonas aeruginosa infection in cystic fibrosis patients
    • Lee TW, Brownlee KG, Conway SP, Denton M, Littlewood JM. Evaluation of a new definition for chronic Pseudomonas aeruginosa infection in cystic fibrosis patients. J Cyst Fibros 2003; 2:29-34.
    • (2003) J Cyst Fibros , vol.2 , pp. 29-34
    • Lee, T.W.1    Brownlee, K.G.2    Conway, S.P.3    Denton, M.4    Littlewood, J.M.5
  • 14
    • 0027752448 scopus 로고
    • Pulmonary function growth velocity in children 6 to 18 years of age
    • Wang X, Dockery DW, Wypij D, et al. Pulmonary function growth velocity in children 6 to 18 years of age. Am Rev Respir Dis 1993; 148(6 pt 1):1502-8.
    • (1993) Am Rev Respir Dis , vol.148 , Issue.6 , pp. 1502-1508
    • Wang, X.1    Dockery, D.W.2    Wypij, D.3
  • 16
    • 33846284918 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa chronic colonization in cystic fibrosis patients
    • Murray TS, Egan M, Kazmierczak BI. Pseudomonas aeruginosa chronic colonization in cystic fibrosis patients. Curr Opin Pediatr 2007; 19:83-8.
    • (2007) Curr Opin Pediatr , vol.19 , pp. 83-88
    • Murray, T.S.1    Egan, M.2    Kazmierczak, B.I.3
  • 17
    • 0028920643 scopus 로고
    • Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface
    • Imundo L, Barasch J, Prince A, Al-Awqati Q. Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface. Proc Natl Acad Sci U S A 1995; 92:3019-23.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3019-3023
    • Imundo, L.1    Barasch, J.2    Prince, A.3    Al-Awqati, Q.4
  • 18
    • 0034255014 scopus 로고    scopus 로고
    • Role of the cystic fibrosis transmembrane conductance regulator in innate immunity to Pseudomonas aeruginosa infections
    • Pier GB. Role of the cystic fibrosis transmembrane conductance regulator in innate immunity to Pseudomonas aeruginosa infections. Proc Natl Acad Sci U S A 2000; 97:8822-8.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8822-8828
    • Pier, G.B.1
  • 19
    • 33745034717 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa pyocyanin inactivates lung epithelial vacuolar ATPase-dependent cystic fibrosis transmembrane conductance regulator expression and localization
    • Kong F, Young L, Chen Y, et al. Pseudomonas aeruginosa pyocyanin inactivates lung epithelial vacuolar ATPase-dependent cystic fibrosis transmembrane conductance regulator expression and localization. Cell Microbiol 2006; 8:1121-33.
    • (2006) Cell Microbiol , vol.8 , pp. 1121-1133
    • Kong, F.1    Young, L.2    Chen, Y.3
  • 20
    • 0037076416 scopus 로고    scopus 로고
    • CFTR is a pattern recognition molecule that extracts pseudomonas aeruginosa LPS from the outer membrane into epithelial cells and activates NF-kappa B translocation
    • Schroeder TH, Lee MM, Yacono PW, et al. CFTR is a pattern recognition molecule that extracts Pseudomonas aeruginosa LPS from the outer membrane into epithelial cells and activates NF-kappa B translocation. Proc Natl Acad Sci U S A 2002; 99:6907-12.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6907-6912
    • Schroeder, T.H.1    Lee, M.M.2    Yacono, P.W.3
  • 21
    • 84863476402 scopus 로고    scopus 로고
    • Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung
    • Pezzulo AA, Tang XX, Hoegger MJ, et al. Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung. Nature 2012; 487:109-13.
    • (2012) Nature , vol.487 , pp. 109-113
    • Pezzulo, A.A.1    Tang, X.X.2    Hoegger, M.J.3
  • 22
    • 84926083232 scopus 로고    scopus 로고
    • Antibacterial properties of the CFTR potentiator ivacaftor
    • Reznikov LR, Abou Alaiwa MH, Dohrn CL, et al. Antibacterial properties of the CFTR potentiator ivacaftor. J Cyst Fibros 2014; 13:515-9.
    • (2014) J Cyst Fibros , vol.13 , pp. 515-519
    • Reznikov, L.R.1    Abou Alaiwa, M.H.2    Dohrn, C.L.3
  • 23
    • 33748146503 scopus 로고    scopus 로고
    • CFTR regulates phagosome acidification in macrophages and alters bactericidal activity
    • Di A, Brown ME, Deriy LV, et al. CFTR regulates phagosome acidification in macrophages and alters bactericidal activity. Nat Cell Biol 2006; 8:933-44.
    • (2006) Nat Cell Biol , vol.8 , pp. 933-944
    • Di, A.1    Brown, M.E.2    Deriy, L.V.3
  • 24
    • 33845542156 scopus 로고    scopus 로고
    • Effect of allergic bronchopulmonary aspergillosis on lung function in children with cystic fibrosis
    • Kraemer R, Delosea N, Ballinari P, Gallati S, Crameri R. Effect of allergic bronchopulmonary aspergillosis on lung function in children with cystic fibrosis. Am J Respir Crit Care Med 2006; 174:1211-20.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 1211-1220
    • Kraemer, R.1    Delosea, N.2    Ballinari, P.3    Gallati, S.4    Crameri, R.5
  • 25
    • 77950682572 scopus 로고    scopus 로고
    • The changing microbial epidemiology in cystic fibrosis
    • Lipuma JJ. The changing microbial epidemiology in cystic fibrosis. Clin Microbiol Rev 2010; 23:299-323.
    • (2010) Clin Microbiol Rev , vol.23 , pp. 299-323
    • Lipuma, J.J.1
  • 26
    • 67449104896 scopus 로고    scopus 로고
    • Occurrence and relevance of filamentous fungi in respiratory secretions of patients with cystic fibrosis- A review
    • Pihet M, Carrere J, Cimon B, et al. Occurrence and relevance of filamentous fungi in respiratory secretions of patients with cystic fibrosis- a review. Med Mycol 2009; 47:387-97.
    • (2009) Med Mycol , vol.47 , pp. 387-397
    • Pihet, M.1    Carrere, J.2    Cimon, B.3
  • 27
    • 84935455468 scopus 로고    scopus 로고
    • Effects of ivacaftor on airway microbiome and inflammation in G551D patients
    • Sagel SD, Harris JK,Wagner BD, et al. Effects of ivacaftor on airway microbiome and inflammation in G551D patients. Pediatr Pulmonol 2013; 48(S36): 285.
    • (2013) Pediatr Pulmonol , vol.48 , Issue.S36 , pp. 285
    • Sagel, S.D.1    Harris, J.K.2    Wagner, B.D.3
  • 28
    • 84888059844 scopus 로고    scopus 로고
    • The predictive potential of the sweat chloride test in cystic fibrosis patients with the G551D mutation
    • Seliger VI, Rodman D, Van Goor F, Schmelz A, Mueller P. The predictive potential of the sweat chloride test in cystic fibrosis patients with the G551D mutation. J Cyst Fibros 2013; 12:706-13.
    • (2013) J Cyst Fibros , vol.12 , pp. 706-713
    • Seliger, V.I.1    Rodman, D.2    Van Goor, F.3    Schmelz, A.4    Mueller, P.5
  • 29
    • 0037132876 scopus 로고    scopus 로고
    • Bias and causal associations in observational research
    • Grimes DA, Schulz KF. Bias and causal associations in observational research. Lancet 2002; 359:248-52.
    • (2002) Lancet , vol.359 , pp. 248-252
    • Grimes, D.A.1    Schulz, K.F.2
  • 30
    • 0035253464 scopus 로고    scopus 로고
    • Longitudinal assessment of Pseudomonas aeruginosa in young children with cystic fibrosis
    • Burns JL, Gibson RL, McNamara S, et al. Longitudinal assessment of Pseudomonas aeruginosa in young children with cystic fibrosis. J Infect Dis 2001; 183:444-52.
    • (2001) J Infect Dis , vol.183 , pp. 444-452
    • Burns, J.L.1    Gibson, R.L.2    McNamara, S.3
  • 31
    • 12844270608 scopus 로고    scopus 로고
    • Longitudinal development of mucoid pseudomonas aeruginosa infection and lung disease progression in children with cystic fibrosis
    • Li Z, Kosorok MR, Farrell PM, et al. Longitudinal development of mucoid Pseudomonas aeruginosa infection and lung disease progression in children with cystic fibrosis. JAMA 2005; 293:581-8.
    • (2005) JAMA , vol.293 , pp. 581-588
    • Li, Z.1    Kosorok, M.R.2    Farrell, P.M.3
  • 32
    • 0036320272 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa and other predictors of mortality and morbidity in young children with cystic fibrosis
    • Emerson J, Rosenfeld M, McNamara S, Ramsey B, Gibson RL. Pseudomonas aeruginosa and other predictors of mortality and morbidity in young children with cystic fibrosis. Pediatr Pulmonol 2002; 34: 91-100.
    • (2002) Pediatr Pulmonol , vol.34 , pp. 91-100
    • Emerson, J.1    Rosenfeld, M.2    McNamara, S.3    Ramsey, B.4    Gibson, R.L.5
  • 33
    • 1642515022 scopus 로고    scopus 로고
    • Reduction in prevalence of chronic Pseudomonas aeruginosa infection at a regional pediatric cystic fibrosis center
    • Lee TW, Brownlee KG, Denton M, Littlewood JM, Conway SP. Reduction in prevalence of chronic Pseudomonas aeruginosa infection at a regional pediatric cystic fibrosis center. Pediatr Pulmonol 2004; 37: 104-10.
    • (2004) Pediatr Pulmonol , vol.37 , pp. 104-110
    • Lee, T.W.1    Brownlee, K.G.2    Denton, M.3    Littlewood, J.M.4    Conway, S.P.5
  • 34
    • 70349815600 scopus 로고    scopus 로고
    • Respiratory microbiology of patients with cystic fibrosis in the united states, 1995 to 2005
    • Razvi S, Quittell L, Sewall A, Quinton H, Marshall B, Saiman L. Respiratory microbiology of patients with cystic fibrosis in the United States, 1995 to 2005. Chest 2009; 136:1554-60.
    • (2009) Chest , vol.136 , pp. 1554-1560
    • Razvi, S.1    Quittell, L.2    Sewall, A.3    Quinton, H.4    Marshall, B.5    Saiman, L.6
  • 35
    • 80052511405 scopus 로고    scopus 로고
    • Comparative efficacy and safety of 4 randomized regimens to treat early Pseudomonas aeruginosa infection in children with cystic fibrosis
    • Treggiari MM, Retsch-Bogart G, Mayer-Hamblett N, et al. Comparative efficacy and safety of 4 randomized regimens to treat early Pseudomonas aeruginosa infection in children with cystic fibrosis. Arch Pediatr Adolesc Med 2011; 165:847-56.
    • (2011) Arch Pediatr Adolesc Med , vol.165 , pp. 847-856
    • Treggiari, M.M.1    Retsch-Bogart, G.2    Mayer-Hamblett, N.3
  • 36
    • 55549102981 scopus 로고    scopus 로고
    • Early aggressive eradication therapy for intermittent pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience
    • Hansen CR, Pressler T, Hoiby N. Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience. J Cyst Fibros 2008; 7: 523-30.
    • (2008) J Cyst Fibros , vol.7 , pp. 523-530
    • Hansen, C.R.1    Pressler, T.2    Hoiby, N.3
  • 37
    • 2642712510 scopus 로고    scopus 로고
    • Placebo-controlled, doubleblind, randomized study of aerosolized tobramycin for early treatment of pseudomonas aeruginosa colonization in cystic fibrosis
    • Wiesemann HG, Steinkamp G, Ratjen F, et al. Placebo-controlled, doubleblind, randomized study of aerosolized tobramycin for early treatment of Pseudomonas aeruginosa colonization in cystic fibrosis. Pediatr Pulmonol 1998; 25:88-92.
    • (1998) Pediatr Pulmonol , vol.25 , pp. 88-92
    • Wiesemann, H.G.1    Steinkamp, G.2    Ratjen, F.3
  • 38
    • 0037445216 scopus 로고    scopus 로고
    • Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis
    • Gibson RL, Emerson J, McNamara S, et al. Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis. Am J Respir Crit Care Med 2003; 167:841-9.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 841-849
    • Gibson, R.L.1    Emerson, J.2    McNamara, S.3
  • 39
    • 84855892151 scopus 로고    scopus 로고
    • Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosis
    • Mayer-Hamblett N, Kronmal RA, Gibson RL, et al. Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosis. Pediatr Pulmonol 2012; 47:125-34.
    • (2012) Pediatr Pulmonol , vol.47 , pp. 125-134
    • Mayer-Hamblett, N.1    Kronmal, R.A.2    Gibson, R.L.3
  • 40
    • 0025868478 scopus 로고
    • Prevention of chronic Pseudomonas aeruginosa colonisation in cystic fibrosis by early treatment
    • Valerius NH, Koch C, Hoiby N. Prevention of chronic Pseudomonas aeruginosa colonisation in cystic fibrosis by early treatment. Lancet 1991; 338:725-6.
    • (1991) Lancet , vol.338 , pp. 725-726
    • Valerius, N.H.1    Koch, C.2    Hoiby, N.3
  • 41
    • 0030995361 scopus 로고    scopus 로고
    • Antibiotic treatment of initial colonization with Pseudomonas aeruginosa postpones chronic infection and prevents deterioration of pulmonary function in cystic fibrosis
    • Frederiksen B, Koch C, Hoiby N. Antibiotic treatment of initial colonization with Pseudomonas aeruginosa postpones chronic infection and prevents deterioration of pulmonary function in cystic fibrosis. Pediatr Pulmonol 1997; 23:330-5.
    • (1997) Pediatr Pulmonol , vol.23 , pp. 330-335
    • Frederiksen, B.1    Koch, C.2    Hoiby, N.3
  • 42
    • 0032797445 scopus 로고    scopus 로고
    • Pulmonary outcome in cystic fibrosis is influenced primarily by mucoid Pseudomonas aeruginosa infection and immune status and only modestly by genotype
    • Parad RB, Gerard CJ, Zurakowski D, Nichols DP, Pier GB. Pulmonary outcome in cystic fibrosis is influenced primarily by mucoid Pseudomonas aeruginosa infection and immune status and only modestly by genotype. Infect Immun 1999; 67:4744-50.
    • (1999) Infect Immun , vol.67 , pp. 4744-4750
    • Parad, R.B.1    Gerard, C.J.2    Zurakowski, D.3    Nichols, D.P.4    Pier, G.B.5
  • 43
    • 0036708203 scopus 로고    scopus 로고
    • Early infection and progression of cystic fibrosis lung disease
    • Koch C. Early infection and progression of cystic fibrosis lung disease. Pediatr Pulmonol 2002; 34:232-6.
    • (2002) Pediatr Pulmonol , vol.34 , pp. 232-236
    • Koch, C.1
  • 44
    • 0037067169 scopus 로고    scopus 로고
    • Respiratory infections with Pseudomonas aeruginosa in children with cystic fibrosis: Early detection by serology and assessment of risk factors
    • West SE, Zeng L, Lee BL, et al. Respiratory infections with Pseudomonas aeruginosa in children with cystic fibrosis: early detection by serology and assessment of risk factors. JAMA 2002; 287:2958-67.
    • (2002) JAMA , vol.287 , pp. 2958-2967
    • West, S.E.1    Zeng, L.2    Lee, B.L.3
  • 45
    • 59649123905 scopus 로고    scopus 로고
    • Acquisition and eradication of Paeruginosa in young children with cystic fibrosis
    • Douglas TA, Brennan S, Gard S, et al. Acquisition and eradication of P. aeruginosa in young children with cystic fibrosis. Eur Respir J 2009; 33:305-11.
    • (2009) Eur Respir J , vol.33 , pp. 305-311
    • Douglas, T.A.1    Brennan, S.2    Gard, S.3
  • 46
    • 77953299585 scopus 로고    scopus 로고
    • Can mucoid Pseudomonas aeruginosa be eradicated in children with cystic fibrosis
    • McPherson H, Rosenthal M, Bush A. Can mucoid Pseudomonas aeruginosa be eradicated in children with cystic fibrosis? Pediatr Pulmonol 2010; 45:566-8.
    • (2010) Pediatr Pulmonol , vol.45 , pp. 566-568
    • McPherson, H.1    Rosenthal, M.2    Bush, A.3
  • 47
    • 84867744034 scopus 로고    scopus 로고
    • Clearance of initial mucoid Pseudomonas aeruginosa in patients with cystic fibrosis
    • Troxler RB, Hoover WC, Britton LJ, Gerwin AM, Rowe SM. Clearance of initial mucoid Pseudomonas aeruginosa in patients with cystic fibrosis. Pediatr Pulmonol 2012; 47:1113-22.
    • (2012) Pediatr Pulmonol , vol.47 , pp. 1113-1122
    • Troxler, R.B.1    Hoover, W.C.2    Britton, L.J.3    Gerwin, A.M.4    Rowe, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.