Occurrence and relevance of filamentous fungi in respiratory secretions of patients with cystic fibrosis - A review

Medical Mycology

Volumn 47, Issue 4, 2009, Pages 387-397

  Pihet, Marc ^a,b   Carrere, Jacqueline ^c   Cimon, Bernard ^a,b   Chabasse, Dominique ^a,b   Delhaes, Laurence ^d   Symoens, Francoise ^e   Bouchara, Jean Philippe ^a,b  

^a UNIVERSITÉ D'ANGERS   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

^c Hopital Renee Sabran   (France)

^d LILLE UNIVERSITY HOSPITAL   (France)

^e SCIENTIFIC INSTITUTE OF PUBLIC HEALTH   (Belgium)

Author keywords

Airway colonization; Aspergillus fumigatus; Cystic fibrosis; Filamentous fungi; Respiratory infections; Scedosporium apiospermum

Indexed keywords

INTERLEUKIN 10; VORICONAZOLE;

ACROPHIALOPHORA FUSISPORA; ASPERGILLUS FLAVUS; ASPERGILLUS FUMIGATUS; ASPERGILLUS NIDULANS; ASPERGILLUS TERREUS; CANDIDA ALBICANS; CONFERENCE PAPER; CYSTIC FIBROSIS; DISEASE ASSOCIATION; EXOPHIALA; EXOPHIALA DERMATIDIS; FUNGAL COLONIZATION; FUNGAL VIRULENCE; FUNGUS; FUNGUS CULTURE; FUNGUS ISOLATION; GENETIC RISK; HUMAN; INFECTION RISK; LUNG ASPERGILLOSIS; LUNG MYCOSIS; NONHUMAN; SCEDOSPORIUM; SCEDOSPORIUM APIOSPERMUM; SCEDOSPORIUM PROLIFICANS; CLASSIFICATION; ISOLATION AND PURIFICATION; MICROBIOLOGY; PREVALENCE; REVIEW;

ACROPHIALOPHORA; ASPERGILLUS FLAVUS; ASPERGILLUS FUMIGATUS; ASPERGILLUS TERREUS; CANDIDA ALBICANS; EMERICELLA NIDULANS; EXOPHIALA DERMATITIDIS; FUNGI; PENICILLIUM; PSEUDALLESCHERIA BOYDII; SCEDOSPORIUM PROLIFICANS;

CYSTIC FIBROSIS; FUNGI; HUMANS; LUNG DISEASES, FUNGAL; PREVALENCE;

EID: 67449104896     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.1080/13693780802609604     Document Type: Conference Paper

References (91)

1. Bellis G, Cazes MH, Parant A, et al. Cystic fibrosis mortality trends in France. J Cyst Fibros 2007; 6: 179-186.
2. Koch C, Høiby N. Diagnosis and treatment of cystic fibrosis. Respiration 2000; 67: 239-247.
3. Mariani-Kurkdjian P, Bingen E. Pathogenic bacteria in cystic fibrosis. Arch Pediatr 2003; 10 (Suppl. 2): 342s-346s.
4. Nagano Y, Millar BC, Johnson E, et al. Fungal infections in patients with cystic fibrosis. Rev Med Microbiol 2007; 18: 11-16.
5. Burns JL, Emerson J, Stapp JR, et al. Microbiology of sputum from patients at cystic fibrosis centers in the United States. Clin Infect Dis 1998; 27: 158-163.
6. Nelson LA, Callerame ML, Schwartz RH. Aspergillosis and atopy in cystic fibrosis. Am Rev Respir Dis 1979; 120: 863-873.
7. Laufer P, Fink JN, Bruns WT, et al. Allergic bronchopulmonary aspergillosis in cystic fibrosis. J Allergy Clin Immunol 1984; 73: 44-48.
8. Bauernfeind A, Bertele RM, Harms K, et al. Qualitative and quantitative microbiological analysis of sputa of 102 patients with cystic fibrosis. Infection 1987; 15: 270-277.
9. Simmonds EJ, Littlewood JM, Evans EG. Cystic fibrosis and allergic bronchopulmonary aspergillosis. Arch Dis Child 1990; 65: 507-511.
10. Marchant JL, Warner JO, Bush A. Rise in total IgE as an indicator of allergic bronchopulmonary aspergillosis in cystic fibrosis. Thorax 1994; 49: 1002-1005.
11. Mroueh S, Spock A. Allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. Chest 1994; 105: 32-36.
12. Becker JW, Burke W, McDonald G, et al. Prevalence of allergic bronchopulmonary aspergillosis and atopy in adult patients with cystic fibrosis. Chest 1996; 109: 1536-1540.
13. Milla CE, Wielinski CL, Regelmann WE. Clinical significance of the recovery of Aspergillus species from the respiratory secretions of cystic fibrosis patients. Pediatr Pulmonol 1996; 21: 6-10.
14. Hutcheson PS, Knutsen AP, Rejent AJ, Slavin RG. A 12-year longitudinal study of Aspergillus sensitivity in patients with cystic fibrosis. Chest 1996; 110: 363-366.
15. Cimon B, Carrère J, Chazalette JP, et al. Fungal colonization and immune response to fungi in cystic fibrosis. J Mycol Méd 1995; 5: 211-216.
16. Cimon B, Carrère J, Chazalette JP, et al. [Bronchopulmonary mycoses in cystic fibrosis. Results of a five-year longitudinal study]. J Mycol Méd 2000; 10: 128-135. [In French.]
17. Skov M, Koch C, Reimert CM, Poulsen LK. Diagnosis of allergic bronchopulmonary aspergillosis (ABPA) in cystic fibrosis. Allergy 2000; 55: 50-58.
18. Bakare N, Rickerts V, Bargon J, Just-Nubling G. Prevalence of Aspergillus fumigatus and other fungal species in the sputum of adult patients with cystic fibrosis. Mycoses 2003; 46: 19-23.
19. Taccetti G, Procopio E, Marianelli L, et al. Allergic bronchopulmonary aspergillosis in Italian cystic fibrosis patients: prevalence and percentage of positive tests in the employed diagnostic criteria. Eur J Epidemiol 2000; 16: 837-842.
20. Skov M, McKay K, Koch C, Cooper PJ. Prevalence of allergic bronchopulmonary aspergillosis in cystic fibrosis in an area with a high frequency of atopy. Respir Med 2005; 99: 887-893.
21. Valenza G, Tappe D, Turnwald D, et al. Prevalence and antimicrobial susceptibility of microorganisms isolated from sputa of patients with cystic fibrosis. J Cyst Fibros 2008; 7: 123-127.
22. Bouchara JP, Sanchez M, Esnault K, Tronchin G. Interactions between Aspergillus fumigatus and host matrix proteins. Contrib Microbiol 1999; 2: 167-181.
23. Tronchin G, Esnault K, Renier G, et al. Expression and identification of a laminin-binding protein in Aspergillus fumigatus conidia. Infect Immun 1997; 65: 9-15.
24. Gil ML, Peñalver MC, Lopez-Ribot JL, O'Connor JE, Martinez JP. Binding of extracellular matrix proteins to Aspergillus fumigatus conidia. Infect Immun 1996; 64: 5239-5247.
25. Tomee JF, Wierenga AT, Hiemstra PS, Kauffman HK. Proteases from Aspergillus fumigatus induce release of proinflammatory cytokines and cell detachment in airway epithelial cell lines. J Infect Dis 1997; 176: 300-303.
26. Sole A, Vicente R, Morant P, et al. Lung transplantation for cystic fibrosis: Infectious events. Med Clin (Barc) 2006; 126 255-258.
27. Iversen M, Burton CM, Vand S, et al. Aspergillus infection in lung transplant patients: Incidence and prognosis. Eur J Clin Microbiol Infect Dis 2007; 26: 879-886.
28. Mastella G, Rainisio M, Harms HK, et al. Allergic bronchopulmonary aspergillosis in cystic fibrosis. A European epidemiological study. Epidemiologic Registry of Cystic Fibrosis. Eur Respir J 2000; 16: 464-471.
29. Stevens DA, Moss RB, Kurup VP, et al. Allergic bronchopulmonary aspergillosis in cystic fibrosis - state of the art: Cystic Fibrosis Foundation Consensus Conference. Clin Infect Dis 2003; 37 (Suppl. 3): S225-264.
30. Chauhan B, Santiago L, Hutcheson PS, et al. Evidence for the involvement of two different MHC class II regions in susceptibility or protection in allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 2000; 106: 723-729.
31. Knutsen AP, Kariuki B, Consolino JD, Warrier MR. IL-4 alpha chain receptor (IL-4Rα) polymorphisms in allergic bronchopulmonary aspergillosis. Clin Mol Allergy 2006; 4: 3.
32. Brouard J, Knauer N, Boelle PY, et al. Influence of interleukin-10 on Aspergillus fumigatus infection in patients with cystic fibrosis. J Infect Dis 2005; 191: 1988-1991.
33. Cimon B, Symoens F, Zouhair R, et al. Molecular epidemiology of airway colonisation by Aspergillus fumigatus in cystic fibrosis patients. J Med Microbiol 2001; 50: 367-374.
34. Schønheyder H, Jensen T, Høiby N, Koch C. Serum antibodies to Aspergillus fumigatus catalase in patients with cystic fibrosis. Eur J Clin Microbiol Infect Dis 1988; 7: 40-44.
35. Neuvéglise C, Sarfati J, Debeaupuis JP, et al. Longitudinal study of Aspergillus fumigatus strains isolated from cystic fibrosis patients. Eur J Clin Microbiol Infect Dis 1997; 16: 747-750.
36. Vanhee LM, Symoens F, Bouchara JP, Nelis HJ, Coenye T. High-resolution genotyping of Aspergillus fumigatus isolates recovered from chronically colonised patients with cystic fibrosis. Eur J Clin Microbiol Infect Dis 2008; 27: 1005-1007.
37. Cimon B, Zouhair R, Symoens F, et al. Aspergillus terreus in a cystic fibrosis clinic: Environmental distribution and patient colonization pattern. J Hosp Infect 2003; 53: 81-82.
38. Symoens F, Bouchara JP, Heinemann S, Nolard N. Molecular typing of Aspergillus terreus isolates by random amplification of polymorphic DNA. J Hosp Infect 2000; 44: 273-280.
39. Guarro J, Kantarcioglu AS, Horré R, et al. Scedosporium apiospermum: Changing clinical spectrum of a therapy-refractory opportunist. Med Mycol 2006; 44: 295-327.
40. Chabasse D, Bouchara JP, Chazalette JP, et al. [Cystic fibrosis and fungal colonization by Scedosporium apiospermum. About three cases]. J Mycol Méd 1991; 1: 152-155. [In French.]
41. Cimon B, Carrere J, Vinatier JF, et al. Clinical significance of Scedosporium apiospermum in patients with cystic fibrosis. Eur J Clin Microbiol Infect Dis 2000; 19: 53-56.
42. Williamson EC, Speers D, Arthur IH, et al. Molecular epidemiology of Scedosporium apiospermum infection determined by PCR amplification of ribosomal intergenic spacer sequences in patients with chronic lung disease. J Clin Microbiol 2001; 39: 47-50.
43. Rainer J, Mayr A, Lass-Flörl C, Dierich MP. Abundance of P. boydii in CF-patients, detected with a semi-selective isolation method. Presented at the 2nd Meeting ECMM/ISHAM Working Group on Pseudallescheria/Scedosporium infections, Angers (France), 7-8 June 2007.
44. Rainer J, Kaltseis J, de Hoog SG, Summerbell RC. Efficacy of a selective isolation procedure for members of the Pseudallescheria boydii complex. Antonie Van Leeuwenhoek 2008; 93: 315-322.
45. de Hoog GS, Marvin-Sikkema FD, Lahpoor GA, et al. Ecology and physiology of the emerging opportunistic fungi Pseudallescheria boydii and Scedosporium prolificans. Mycoses 1994; 37 71-78.
46. Claußen M, Schmidt S. Biodegradation of phenol and p-cresol by the hyphomycete Scedosporium apiospermum. Res Microbiol 1998; 149: 399-406.
47. Claußen M, Schmidt S. Biodegradation of phenylbenzoate and some of its derivatives by Scedosporium apiospermum. Res Microbiol 199: 150: 413-420.
48. Beguin H, Nolard N. Mould diversity in homes. Air and surface analysis of 130 dwellings. Aerobiologica 1994; 10: 157-166.
49. Cimon B, Zouhair R, Licznar-Fajardo P, et al. Scedosporium apiospermum: Environmental study at home of patients with cystic fibrosis. Presented at the 2nd Meeting ECMM/ISHAM Working Group on Pseudallescheria/Scedosporium infections, Angers (France), 7-8 June 2007.
50. Summerbell RC, Krajden S, Kane J. Potted plants in hospitals as reservoirs of pathogenic fungi. Mycopathologia 1989; 106: 13-22.
51. Pinto MR, de Sá AC, Limongi CL, et al. Involvement of peptidorhamnomannan in the interaction of Pseudallescheria boydii and HEp2 cells. Microbes Infect 2004; 6: 1259-1267.
52. da Silva BA, dos Santos AL, Barreto-Bergter E, Pinto MR. Extracellular peptidase in the fungal pathogen Pseudallescheria boydii. Curr Microbiol 2006; 53: 18-22.
53. Silva BA, Pinto MR, Soares RM, Barreto-Bergter E, Santos AL. Pseudallescheria boydii releases metallopeptidases capable of cleaving several proteinaceous compounds. Res Microbiol 2006; 157: 425-432.
54. de Hoog GS, Marvin-Sikkema FD, Lahpoor GA, et al. Ecology and physiology of the emerging opportunistic fungi Pseudallescheria boydii and Scedosporium prolificans. Mycoses 1994; 37 71-78.
55. Larcher G, Cimon B, Symoens F, et al. A 33 kDa serine proteinase from Scedosporium apiospermum. Biochem J 1996; 315: 119-126.
56. Lima OC, Larcher G, Vandeputte P, et al. Molecular cloning and biochemical characterization of a Cu, Zn-superoxide dismutase from Scedosporium apiospermum. Microbes Infect 2007; 9: 558-565.
57. Defontaine A, Zouhair R, Cimon B, et al. Genotyping study of Scedosporium apiospermum isolates from patients with cystic fibrosis. J Clin Microbiol 2002; 40: 2108-2114.
58. Hennequin C, Benailly N, Silly C, et al. In vitro susceptibilities to amphotericin B, itraconazole, and miconazole of filamentous fungi isolated from patients with cystic fibrosis. Antimicrob Agents Chemother 1997; 41: 2064-2066.
59. Gilgado F, Serena C, Cano J, Gené J, Guarro J. Antifungal susceptibilities of the species of the Pseudallescheria boydii complex. Antimicrob Agents Chemother 2006; 50: 4211-4213.
60. Symoens F, Knoop C, Schrooyen M, et al. Disseminated Scedosporium apiospermum infection in a cystic fibrosis patient after double-lung transplantation. J Heart Lung Transplant 2006; 25 603-607.
61. Zouhair R, Defontaine A, Ollivier C, et al. Typing of Scedosporium apiospermum by multilocus enzyme electrophoresis and random amplification of polymorphic DNA. J Med Microbiol 2001; 50: 925-932.
62. Guignard S, Hubert D, Dupont B, et al. Multifocal Scedosporium apiospermum spondylitis in a cystic fibrosis patient. J Cyst Fibros 2008; 7: 89-91.
63. Gilgado F, Cano J, Gené J, Guarro J. Molecular phylogeny of the Pseudallescheria boydii species complex: Proposal of two new species. J Clin Microbiol 2005; 43: 4930-4942.
64. Cano J, Gilgado F, Gené J, Guarro J. Phenotypic characterization and new species in Pseudallescheria. Presented at the 2nd Meeting ECMM/ISHAM Working Group on Pseudallescheria/Scedosporium infections, Angers (France), 7-8 June 2007.
65. Gilgado F, Cano J, Gené J, Sutton DA, Guarro J. Molecular and phenotypic data supporting distinct species statuses for Scedosporium apiospermum and Pseudallescheria boydii and the proposed new species Scedosporium dehoogii. J Clin Microbiol 2008; 46 766-771.
66. Maertens J, Lagrou K, Deweerdt H, et al. Disseminated infection by Scedosporium prolificans: An emerging fatality among haematology patients. Case report and review. Ann Hematol 2000; 79: 340-344.
67. García E, Rodríguez V, Gartner S, Gené J. [Isolation of Scedosporium prolificans in patients with cystic fibrosis]. Enferm Infecc Microbiol Clin 1998; 16: 488-489. [In Spanish.]
68. del Palacio A, Garau M, Amor E, et al. Case reports. Transient colonization with Scedosporium prolificans. Report of four cases in Madrid. Mycoses 2001; 44: 321-325.
69. Lopez L, Gaztelurrutia L, Cuenca-Estrella M, et al. [Infection and colonization by Scedosporium prolificans]. Enferm Infecc Microbiol Clin 2001; 19: 308-313. [In Spanish.]
70. Sole M, Cano J, Rodriguez-Tudela JL, et al. Molecular typing of clinical and environmental isolates of Scedosporium prolificans by inter-simple-sequence-repeat polymerase chain reaction. Med Mycol 2003; 41: 293-300.
71. Delhaes L, Harun A, Chen SC, et al. Molecular typing of Australian Scedosporium isolates showing genetic variability and numerous S. aurantiacum. Emerg Infect Dis 2008; 14: 282-290.
72. Vagefi MR, Kim ET, Alvarado RG, et al. Bilateral endogenous Scedosporium prolificans endophthalmitis after lung transplantation Am J Ophthalmol 2005; 139: 370-373.
73. Haase G, Skopnik H, Kusenbach G. Exophiala dermatitidis infection in cystic fibrosis. Lancet 1990; 336: 188-189.
74. Haase G, Skopnik H, Groten T, Kusenbach G, Posselt HG. Long-term fungal cultures from sputum of patients with cystic fibrosis. Mycoses 1991; 34: 373-376.
75. Horré R, Schaal KP, Siekmeier R, et al. Isolation of fungi, especially Exophiala dermatitidis, in patients suffering from cystic fibrosis. A prospective study. Respiration 2004; 71: 360-366.
76. Kusenbach G, Skopnik H, Haase G, Friedrichs F, Dohmen H. Exophiala dermatitidis pneumonia in cystic fibrosis. Eur J Pediatr 1992; 151: 344-346.
77. Blaschke-Hellmessen R, Lauterbach I, Paul KD, Tintelnot K, Weissbach G. [Detection of Exophiala dermatitidis (Kano) De Hoog 1977 in septicemia of a child with acute lymphatic leukemia and in patients with cystic fibrosis]. Mycoses 1994; 37 (Suppl. 1): 89-96. [In German.]
78. Gigi J, Lebecque P, Reychler G, Symoens F. Exophiala dermatitidis: airway colonisation of the upper respiratory tract in Belgian cystic fibrosis patients. Presented at the Annual Congress of the Belgium Society of Mycology, Brussels (Belgium), 12 April 2008.
79. Koch C, Cuppens H, Rainisio M, et al. European Epidemiologic Registry of Cystic Fibrosis (ERCF): Comparison of major disease manifestations between patients with different classes of mutations. Pediatr Pulmonol 2001; 31: 1-12.
80. Matos T, De Hoog GS, De Boer AG, De Crom I, Haase G. High prevalence of the neurotropic Exophiala dermatitidis and related oligotrophic black yeasts in sauna facilities. Mycoses 2002; 45: 373-377.
81. Kerr J. Inhibition of fungal growth by Pseudomonas aeruginosa and Pseudomonas cepacia isolated from patients with cystic fibrosis. J Infect 1994; 28: 305-310.
82. Kerr JR, Taylor GW, Rutman A, et al. Pseudomonas aeruginosa pyocyanin and 1-hydroxyphenazine inhibit fungal growth. J Clin Pathol 1999; 52: 385-387.
83. Cimon B, Carrère J, Chazalette JP, et al. Chronic airway colonization by Penicillium emersonii in a patient with cystic fibrosis. Med Mycol 1999; 37: 291-293.
84. Gonzalez-Escalada A, Del Palacio A, Calvo MT, Gene J, Guarro J. Two cases of scalp wound colonization and respiratory tract by mycelial fungi. Rev Iberoam Micol 2000; 17: 149-151.
85. Shukla PK, Khan ZA, Lal B, Agrawal PK, Srivastava OP. Clinical and experimental keratitis caused by the Collectotrichum state of Glomerella cingulata and Acrophialophora fusispora. Sabouraudia 1983; 21: 137-147.
86. Sutton DA, Sigler L, Kalassian KG, et al. Pulmonary Acrophialophora fusispora: Case history, literature review and mycology. Program and abstracts of 13th Congress of the International Society for Human and Animal Mycology, Salsomaggiore Terme, Parma (Italy), 8-13 June 1997: Abstract 363.
87. Al-Mohsen IZ, Sutton DA, Sigler L, et al. Acrophialophora fusispora brain abscess in a child with acute lymphoblastic leukemia: Review of cases and taxonomy. J Clin Microbiol 2000; 38: 4569-4576.
88. Cimon B, Challier S, Beguin H, et al. Airway colonization by Acrophialophora fusispora in patients with cystic fibrosis. J Clin Microbiol 2005; 43: 1484-1487.
89. Welsh RD, Ely RW. Scopulariopsis chartarum systemic mycosis in a dog. J Clin Microbiol 1999; 37: 2102-2103.
90. Guarro J, Gene J. Acrophialophora fusispora misidentified as Scedosporium prolificans. J Clin Microbiol 2002; 40: 3544; author reply 3545.
91. Sigler L, Sutton DA. Acrophialophora fusispora misidentified as Scedosporium prolificans. J Clin Microbiol 2002; 40: 3544-3545; author reply 3545.