-
1
-
-
17744412173
-
Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial. US Oral Neuraminidase Study Group
-
Treanor, J.J., et al. Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial. US Oral Neuraminidase Study Group. JAMA: the journal of the American Medical Association 283, 1016-1024 (2000).
-
(2000)
JAMA: the journal of the American Medical Association
, vol.283
, pp. 1016-1024
-
-
Treanor, J.J.1
-
2
-
-
48649096437
-
Co-morbidities associated with influenza-attributed mortality
-
1994-2000, Canada
-
Schanzer, D.L., Langley, J.M. & Tam, T.W. Co-morbidities associated with influenza-attributed mortality, 1994-2000, Canada. Vaccine 26, 4697-4703 (2008).
-
(2008)
Vaccine
, vol.26
, pp. 4697-4703
-
-
Schanzer, D.L.1
Langley, J.M.2
Tam, T.W.3
-
3
-
-
77956273847
-
Estimates of Deaths Associated with Seasonal Influenza US
-
1976-2007; MMWR.
-
Control, C.f.D. Estimates of Deaths Associated with Seasonal Influenza US, 1976-2007; MMWR., Vol. 59 1057-1062 (2012).
-
(2012)
, vol.59
, pp. 1057-1062
-
-
-
4
-
-
84865307690
-
Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study
-
Dawood, F.S., et al. Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study. The Lancet infectious diseases 12, 687-695 (2012).
-
(2012)
The Lancet infectious diseases
, vol.12
, pp. 687-695
-
-
Dawood, F.S.1
-
5
-
-
38349068756
-
Update on avian influenza A (H5N1) virus infection in humans
-
A.V., et al
-
Writing Committee of the Second World Health Organization Consultation on Clinical Aspects of Human Infection with Avian Influenza, A.V., et al. Update on avian influenza A (H5N1) virus infection in humans. N Engl J Med 358, 261-273 (2008).
-
(2008)
N Engl J Med
, vol.358
, pp. 261-273
-
-
-
6
-
-
79851496686
-
Emerging influenza antiviral resistance threats
-
Hayden, F.G. & de Jong, M.D. Emerging influenza antiviral resistance threats. J Infect Dis 203, 6-10 (2011).
-
(2011)
J Infect Dis
, vol.203
, pp. 6-10
-
-
Hayden, F.G.1
de Jong, M.D.2
-
7
-
-
72049112028
-
Monoclonal antibody-based therapies for microbial diseases
-
Saylor, C., Dadachova, E. & Casadevall, A. Monoclonal antibody-based therapies for microbial diseases. Vaccine 27 Suppl 6, G38-46 (2009).
-
(2009)
Vaccine
, vol.27
, pp. G38-G46
-
-
Saylor, C.1
Dadachova, E.2
Casadevall, A.3
-
8
-
-
77952602676
-
Safety and pharmacokinetics of single intravenous dose of MGAWN1, a novel monoclonal antibody to West Nile virus
-
Beigel, J.H., et al. Safety and pharmacokinetics of single intravenous dose of MGAWN1, a novel monoclonal antibody to West Nile virus. Antimicrob Agents Chemother 54, 2431-2436 (2010).
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2431-2436
-
-
Beigel, J.H.1
-
9
-
-
84935146677
-
Human Monoclonal Antibody MBL-HCV1 Suppresses Return of HCV Following Liver Transplantation: A Randomized
-
Controlled Study, (Submitted).
-
Chung, R., Gordon, F., Curry, M. & Ambrosino, D. Human Monoclonal Antibody MBL-HCV1 Suppresses Return of HCV Following Liver Transplantation: A Randomized, Controlled Study. (Submitted).
-
-
-
Chung, R.1
Gordon, F.2
Curry, M.3
Ambrosino, D.4
-
10
-
-
84935076655
-
A Human Monoclonal to Rabies Virus Provides Protective Neutralizing Activity: Results of a Phase I Study
-
Boston
-
Leav, B., Kulkarni, P., Gogtay, N. & Ambrosino, D. A Human Monoclonal to Rabies Virus Provides Protective Neutralizing Activity: Results of a Phase I Study. in ICAAC (Boston, 2010).
-
(2010)
ICAAC
-
-
Leav, B.1
Kulkarni, P.2
Gogtay, N.3
Ambrosino, D.4
-
12
-
-
17344371596
-
Reduction of respiratory syncytial virus (RSV) in tracheal aspirates in intubated infants by use of humanized monoclonal antibody to RSV F protein
-
Malley, R., et al. Reduction of respiratory syncytial virus (RSV) in tracheal aspirates in intubated infants by use of humanized monoclonal antibody to RSV F protein. J Infect Dis 178, 1555-1561 (1998).
-
(1998)
J Infect Dis
, vol.178
, pp. 1555-1561
-
-
Malley, R.1
-
14
-
-
0026547259
-
Immunoglobulin prophylaxis for hepatitis A
-
Winokur, P.L. & Stapleton, J.T. Immunoglobulin prophylaxis for hepatitis A. Clin Infect Dis 14, 580-586 (1992).
-
(1992)
Clin Infect Dis
, vol.14
, pp. 580-586
-
-
Winokur, P.L.1
Stapleton, J.T.2
-
15
-
-
33750721332
-
Meta-analysis: convalescent blood products for Spanish influenza pneumonia, A future H5N1 treatment?
-
Luke, T.C., Kilbane, E.M., Jackson, J.L. & Hoffman, S.L. Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment? Annals of internal medicine 145, 599-609 (2006).
-
(2006)
Annals of internal medicine
, vol.145
, pp. 599-609
-
-
Luke, T.C.1
Kilbane, E.M.2
Jackson, J.L.3
Hoffman, S.L.4
-
16
-
-
79951821842
-
Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection
-
Hung, I.F., et al. Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection. Clin Infect Dis 52, 447-456 (2011).
-
(2011)
Clin Infect Dis
, vol.52
, pp. 447-456
-
-
Hung, I.F.1
-
17
-
-
84925284996
-
In-depth determination and analysis of the human paired heavy- and lightchain antibody repertoire
-
DeKosky, B.J., et al. In-depth determination and analysis of the human paired heavy- and lightchain antibody repertoire. Nature medicine 21, 86-91 (2015).
-
(2015)
Nature medicine
, vol.21
, pp. 86-91
-
-
DeKosky, B.J.1
-
19
-
-
84904263671
-
Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements
-
Jackson, K.J., et al. Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements. Cell host & microbe 16, 105-114 (2014).
-
(2014)
Cell host & microbe
, vol.16
, pp. 105-114
-
-
Jackson, K.J.1
-
20
-
-
84903476533
-
Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection
-
Mallajosyula, V.V., et al. Influenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protection. Proceedings of the National Academy of Sciences of the United States of America 111, E2514-2523 (2014).
-
(2014)
Proceedings of the National Academy of Sciences of the United States of America
, vol.111
, pp. E2514-2523
-
-
Mallajosyula, V.V.1
-
21
-
-
84921503793
-
Advances in universal influenza virus vaccine design and antibody mediated therapies based on conserved regions of the hemagglutinin
-
Krammer, F., Palese, P. & Steel, J. Advances in universal influenza virus vaccine design and antibody mediated therapies based on conserved regions of the hemagglutinin. Current topics in microbiology and immunology 386, 301-321 (2015).
-
(2015)
Current topics in microbiology and immunology
, vol.386
, pp. 301-321
-
-
Krammer, F.1
Palese, P.2
Steel, J.3
-
22
-
-
84922740556
-
Manipulating the Selection Forces during Affinity Maturation to Generate Cross- Reactive HIV Antibodies
-
Wang, S., et al. Manipulating the Selection Forces during Affinity Maturation to Generate Cross- Reactive HIV Antibodies. Cell 160, 785-797 (2015).
-
(2015)
Cell
, vol.160
, pp. 785-797
-
-
Wang, S.1
-
23
-
-
78649958318
-
Universal antibodies against the highly conserved influenza fusion peptide cross-neutralize several subtypes of influenza A virus
-
Hashem, A.M., et al. Universal antibodies against the highly conserved influenza fusion peptide cross-neutralize several subtypes of influenza A virus. Biochem Biophys Res Commun 403, 247- 251 (2010).
-
(2010)
Biochem Biophys Res Commun
, vol.403
, pp. 247-251
-
-
Hashem, A.M.1
-
24
-
-
80051635697
-
A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses
-
Ekiert, D.C., et al. A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses. Science (2011).
-
(2011)
Science
-
-
Ekiert, D.C.1
-
25
-
-
80053132436
-
Broad neutralization coverage of HIV by multiple highly potent antibodies
-
Walker, L.M., et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature 477, 466-470 (2011).
-
(2011)
Nature
, vol.477
, pp. 466-470
-
-
Walker, L.M.1
-
26
-
-
84866949036
-
Structural and genetic basis for development of broadly neutralizing influenza antibodies
-
Lingwood, D., et al. Structural and genetic basis for development of broadly neutralizing influenza antibodies. Nature 489, 566-570 (2012).
-
(2012)
Nature
, vol.489
, pp. 566-570
-
-
Lingwood, D.1
-
27
-
-
84922225958
-
Rapid development of broadly influenza neutralizing antibodies through redundant mutations
-
Pappas, L., et al. Rapid development of broadly influenza neutralizing antibodies through redundant mutations. Nature 516, 418-422 (2014).
-
(2014)
Nature
, vol.516
, pp. 418-422
-
-
Pappas, L.1
-
28
-
-
77955434077
-
Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses
-
Grandea, A.G., III, et al. Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses. Proc Natl Acad Sci U S A 107, 12658-12663 (2010).
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 12658-12663
-
-
Grandea, A.G.1
-
29
-
-
80051670323
-
A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins
-
Corti, D., et al. A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science 333, 850-856 (2011).
-
(2011)
Science
, vol.333
, pp. 850-856
-
-
Corti, D.1
-
30
-
-
80051635697
-
A highly conserved neutralizing epitope on group 2 influenza A viruses
-
Ekiert, D.C., et al. A highly conserved neutralizing epitope on group 2 influenza A viruses. Science 333, 843-850 (2011).
-
(2011)
Science
, vol.333
, pp. 843-850
-
-
Ekiert, D.C.1
-
31
-
-
64849114224
-
Antibody recognition of a highly conserved influenza virus epitope
-
Ekiert, D.C., et al. Antibody recognition of a highly conserved influenza virus epitope. Science 324, 246-251 (2009).
-
(2009)
Science
, vol.324
, pp. 246-251
-
-
Ekiert, D.C.1
-
32
-
-
84920432764
-
Influenza viral neuraminidase primes bacterial coinfection through TGF-betamediated expression of host cell receptors
-
Li, N., et al. Influenza viral neuraminidase primes bacterial coinfection through TGF-betamediated expression of host cell receptors. Proceedings of the National Academy of Sciences of the United States of America 112, 238-243 (2015).
-
(2015)
Proceedings of the National Academy of Sciences of the United States of America
, vol.112
, pp. 238-243
-
-
Li, N.1
-
33
-
-
58049198443
-
Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells
-
Throsby, M., et al. Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells. PLoS One 3, e3942 (2008).
-
(2008)
PLoS One
, vol.3
-
-
Throsby, M.1
-
34
-
-
62049083943
-
Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses
-
Sui, J., et al. Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol 16, 265-273 (2009).
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 265-273
-
-
Sui, J.1
-
35
-
-
84900431101
-
High-throughput profiling of influenza A virus hemagglutinin gene at singlenucleotide resolution
-
Wu, N.C., et al. High-throughput profiling of influenza A virus hemagglutinin gene at singlenucleotide resolution. Scientific reports 4, 4942 (2014).
-
(2014)
Scientific reports
, vol.4
, pp. 4942
-
-
Wu, N.C.1
-
36
-
-
84859736924
-
Networks link antigenic and receptor-binding sites of influenza hemagglutinin: mechanistic insight into fitter strain propagation
-
Soundararajan, V., et al. Networks link antigenic and receptor-binding sites of influenza hemagglutinin: mechanistic insight into fitter strain propagation. Scientific reports 1, 200 (2011).
-
(2011)
Scientific reports
, vol.1
, pp. 200
-
-
Soundararajan, V.1
-
37
-
-
84880427552
-
An in vivo human-plasmablast enrichment technique allows rapid identification of therapeutic influenza A antibodies
-
Nakamura, G., et al. An in vivo human-plasmablast enrichment technique allows rapid identification of therapeutic influenza A antibodies. Cell host & microbe 14, 93-103 (2013).
-
(2013)
Cell host & microbe
, vol.14
, pp. 93-103
-
-
Nakamura, G.1
-
38
-
-
84924777947
-
Broadly-Neutralizing Anti-Influenza Virus Antibodies: Enhancement of Neutralizing Potency in Polyclonal Mixtures and IgA Backbones
-
He, W., et al. Broadly-Neutralizing Anti-Influenza Virus Antibodies: Enhancement of Neutralizing Potency in Polyclonal Mixtures and IgA Backbones. Journal of virology (2015).
-
(2015)
Journal of virology
-
-
He, W.1
-
39
-
-
84893797938
-
Broadly neutralizing hemagglutinin stalkspecific antibodies require FcgammaR interactions for protection against influenza virus in vivo
-
DiLillo, D.J., Tan, G.S., Palese, P. & Ravetch, J.V. Broadly neutralizing hemagglutinin stalkspecific antibodies require FcgammaR interactions for protection against influenza virus in vivo. Nature medicine 20, 143-151 (2014).
-
(2014)
Nature medicine
, vol.20
, pp. 143-151
-
-
DiLillo, D.J.1
Tan, G.S.2
Palese, P.3
Ravetch, J.V.4
-
40
-
-
84901024170
-
Broadly neutralizing influenza hemagglutinin stem-specific antibody CR8020 targets residues that are prone to escape due to host selection pressure
-
Tharakaraman, K., Subramanian, V., Cain, D., Sasisekharan, V. & Sasisekharan, R. Broadly neutralizing influenza hemagglutinin stem-specific antibody CR8020 targets residues that are prone to escape due to host selection pressure. Cell host & microbe 15, 644-651 (2014).
-
(2014)
Cell host & microbe
, vol.15
, pp. 644-651
-
-
Tharakaraman, K.1
Subramanian, V.2
Cain, D.3
Sasisekharan, V.4
Sasisekharan, R.5
-
41
-
-
84926348347
-
Alternative molecular formats and therapeutic applications for bispecific antibodies
-
Spiess, C., Zhai, Q. & Carter, P.J. Alternative molecular formats and therapeutic applications for bispecific antibodies. Molecular immunology (2015).
-
(2015)
Molecular immunology
-
-
Spiess, C.1
Zhai, Q.2
Carter, P.J.3
-
42
-
-
84910673427
-
A multifunctional bispecific antibody protects against Pseudomonas aeruginosa
-
262ra155
-
DiGiandomenico, A., et al. A multifunctional bispecific antibody protects against Pseudomonas aeruginosa. Science translational medicine 6, 262ra155 (2014).
-
(2014)
Science translational medicine
, vol.6
-
-
DiGiandomenico, A.1
-
43
-
-
84889803644
-
A bispecific antibody against two different epitopes on hepatitis B surface antigen has potent hepatitis B virus neutralizing activity
-
Tan, W., et al. A bispecific antibody against two different epitopes on hepatitis B surface antigen has potent hepatitis B virus neutralizing activity. mAbs 5, 946-955 (2013).
-
(2013)
mAbs
, vol.5
, pp. 946-955
-
-
Tan, W.1
-
44
-
-
84922224963
-
Intra-Spike Crosslinking Overcomes Antibody Evasion by HIV-1
-
Galimidi, R.P., et al. Intra-Spike Crosslinking Overcomes Antibody Evasion by HIV-1. Cell 160, 433-446 (2015).
-
(2015)
Cell
, vol.160
, pp. 433-446
-
-
Galimidi, R.P.1
|