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Volumn 13, Issue 1, 2014, Pages

EGFR phosphorylates and inhibits lung tumor suppressor GPRC5A in lung cancer

Author keywords

EGFR; GPRC5A; Lung cancer; Post translation modification; Tyrosine kinase

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR FAMILY C GROUP 5 MEMBER A; PHENYLALANINE; PROTEIN TYROSINE KINASE; TYROSINE; UNCLASSIFIED DRUG; GPRC5A PROTEIN, HUMAN; PHOSPHOTYROSINE; PROTEIN BINDING;

EID: 84935000709     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-233     Document Type: Article
Times cited : (27)

References (29)
  • 1
    • 0032567334 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel retinoic acid-inducible gene that encodes a putative G protein-coupled receptor
    • Cheng Y, Lotan R: Molecular cloning and characterization of a novel retinoic acid-inducible gene that encodes a putative G protein-coupled receptor. J Biol Chem 1, 273:35008-35015. 10.1074/jbc.273.52.35008
    • (1998) J Biol Chem , vol.273 , pp. 35008-35015
    • Cheng, Y.1    Lotan, R.2
  • 3
    • 0030039909 scopus 로고    scopus 로고
    • Frequent loss of heterozygosity in region of the KIP1 locus in non-small cell lung cancer: evidence for a new tumor suppressor gene on the short arm of chromosome 12
    • Takeuchi S, Mori N, Koike M, Slater J, Park S, Miller CW, Miyoshi I, Koeffler HP: Frequent loss of heterozygosity in region of the KIP1 locus in non-small cell lung cancer: evidence for a new tumor suppressor gene on the short arm of chromosome 12. Cancer Res 1996, 56:738-740.
    • (1996) Cancer Res , vol.56 , pp. 738-740
    • Takeuchi, S.1    Mori, N.2    Koike, M.3    Slater, J.4    Park, S.5    Miller, C.W.6    Miyoshi, I.7    Koeffler, H.P.8
  • 5
    • 84870346520 scopus 로고    scopus 로고
    • G-protein coupled receptor family C, group 5, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer
    • Fujimoto J, Kadara H, Garcia MM, Kabbout M, Behrens C, Liu DD, Lee JJ, Solis LM, Kim ES, Kalhor N, Moran C, Sharafkhaneh A, Lotan R, Wistuba II: G-protein coupled receptor family C, group 1, member A (GPRC5A) expression is decreased in the adjacent field and normal bronchial epithelia of patients with chronic obstructive pulmonary disease and non-small-cell lung cancer. J Thorac Oncol 2012, 7:1747-1754. 10.1097/JTO.0b013e31826bb1ff
    • (2012) J Thorac Oncol , vol.7 , pp. 1747-1754
    • Fujimoto, J.1    Kadara, H.2    Garcia, M.M.3    Kabbout, M.4    Behrens, C.5    Liu, D.D.6    Lee, J.J.7    Solis, L.M.8    Kim, E.S.9    Kalhor, N.10    Moran, C.11    Sharafkhaneh, A.12    Lotan, R.13    Wistuba, R.14
  • 6
    • 77950855142 scopus 로고    scopus 로고
    • Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis
    • Deng J, Fujimoto J, Ye XF, Men TY, Van Pelt CS, Chen YL, Lin XF, Kadara H, Tao Q, Lotan D, Lotan R: Knockout of the tumor suppressor gene Gprc5a in mice leads to NF-kappaB activation in airway epithelium and promotes lung inflammation and tumorigenesis. Cancer Prev Res (Phila) 1, 3:424-437. 10.1158/1940-6207.CAPR-10-0032
    • (2010) Cancer Prev Res (Phila) , vol.3 , pp. 424-437
    • Deng, J.1    Fujimoto, J.2    Ye, X.F.3    Men, T.Y.4    Van Pelt, C.S.5    Chen, Y.L.6    Lin, X.F.7    Kadara, H.8    Tao, Q.9    Lotan, D.10    Lotan, R.11
  • 8
    • 33750324139 scopus 로고    scopus 로고
    • Novel reciprocal regulation of cAMP signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A gene expression
    • Hirano M, Zang L, Oka T, Ito Y, Shimada Y, Nishimura Y, Tanaka T: Novel reciprocal regulation of cAMP signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A gene expression. Biochem Biophys Res Commun 1, 351:185-191. 10.1016/j.bbrc.2006.10.016
    • (2006) Biochem Biophys Res Commun , vol.351 , pp. 185-191
    • Hirano, M.1    Zang, L.2    Oka, T.3    Ito, Y.4    Shimada, Y.5    Nishimura, Y.6    Tanaka, T.7
  • 10
    • 41149154050 scopus 로고    scopus 로고
    • G protein-coupled receptor sorting to endosomes and lysosomes
    • Marchese A, Paing MM, Temple BR, Trejo J: G protein-coupled receptor sorting to endosomes and lysosomes. Annu Rev Pharmacol Toxicol 1, 48:601-629. 10.1146/annurev.pharmtox.48.113006.094646
    • (2008) Annu Rev Pharmacol Toxicol , vol.48 , pp. 601-629
    • Marchese, A.1    Paing, M.M.2    Temple, B.R.3    Trejo, J.4
  • 11
    • 63849209036 scopus 로고    scopus 로고
    • Targeting of G protein-coupled receptors to the plasma membrane in health and disease
    • Ulloa-Aguirre A, Conn PM: Targeting of G protein-coupled receptors to the plasma membrane in health and disease. Front Biosci (Landmark Ed) 2009, 14:973-994.
    • (2009) Front Biosci (Landmark Ed) , vol.14 , pp. 973-994
    • Ulloa-Aguirre, A.1    Conn, P.M.2
  • 12
    • 33947375174 scopus 로고    scopus 로고
    • Physiological roles of G protein-coupled receptor kinases and arrestins
    • Premont RT, Gainetdinov RR: Physiological roles of G protein-coupled receptor kinases and arrestins. Annu Rev Physiol 1, 69:511-534. 10.1146/annurev.physiol.69.022405.154731
    • (2007) Annu Rev Physiol , vol.69 , pp. 511-534
    • Premont, R.T.1    Gainetdinov, R.R.2
  • 13
    • 47849101639 scopus 로고    scopus 로고
    • Location, location, location.site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling
    • Tobin AB, Butcher AJ, Kong KC: Location, location, location.site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling. Trends Pharmacol Sci 1, 29:413-420. 10.1016/j.tips.2008.05.006
    • (2008) Trends Pharmacol Sci , vol.29 , pp. 413-420
    • Tobin, A.B.1    Butcher, A.J.2    Kong, K.C.3
  • 14
    • 0035966002 scopus 로고    scopus 로고
    • Role of tyrosine phosphorylation in ligand-independent sequestration of CXCR4 in human primary monocytes-macrophages
    • Wang J, Guan E, Roderiquez G, Calvert V, Alvarez R, Norcross MA: Role of tyrosine phosphorylation in ligand-independent sequestration of CXCR4 in human primary monocytes-macrophages. J Biol Chem 1, 276:49236-49243. 10.1074/jbc.M108523200
    • (2001) J Biol Chem , vol.276 , pp. 49236-49243
    • Wang, J.1    Guan, E.2    Roderiquez, G.3    Calvert, V.4    Alvarez, R.5    Norcross, M.A.6
  • 15
    • 0034763842 scopus 로고    scopus 로고
    • Highlights in lung cancer
    • Brambilla C, Spiro S: Highlights in lung cancer. Eur Respir J 1, 18:617-618. 10.1183/09031936.01.00238801
    • (2001) Eur Respir J , vol.18 , pp. 617-618
    • Brambilla, C.1    Spiro, S.2
  • 16
    • 0142119289 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis
    • Hirsch FR, Varella-Garcia M, Bunn PA Jr, Di Maria MV, Veve R, Bremmes RM, Baron AE, Zeng C, Franklin WA: Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol 1, 21:3798-3807. 10.1200/JCO.2003.11.069
    • (2003) J Clin Oncol , vol.21 , pp. 3798-3807
    • Hirsch, F.R.1    Varella-Garcia, M.2    Bunn, P.A.3    Di Maria, M.V.4    Veve, R.5    Bremmes, R.M.6    Baron, A.E.7    Zeng, C.8    Franklin, W.A.9
  • 18
    • 34250216633 scopus 로고    scopus 로고
    • Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis
    • Riese DJ 2nd, Gallo RM, Settleman J: Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis. Bioessays 1, 29:558-565. 10.1002/bies.20582
    • (2007) Bioessays , vol.29 , pp. 558-565
    • Riese, D.J.1    Gallo, R.M.2    Settleman, J.3
  • 19
    • 33847323129 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in lung cancer
    • Sharma SV, Bell DW, Settleman J, Haber DA: Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer 1, 7:169-181. 10.1038/nrc2088
    • (2007) Nat Rev Cancer , vol.7 , pp. 169-181
    • Sharma, S.V.1    Bell, D.W.2    Settleman, J.3    Haber, D.A.4
  • 20
    • 0031673803 scopus 로고    scopus 로고
    • Posttranslational modifications of endothelin receptor type B
    • Okamoto Y, Ninomiya H, Masaki T: Posttranslational modifications of endothelin receptor type B. Trends Cardiovasc Med 1, 8:327-329. 10.1016/S1050-1738(98)00027-9
    • (1998) Trends Cardiovasc Med , vol.8 , pp. 327-329
    • Okamoto, Y.1    Ninomiya, H.2    Masaki, T.3
  • 21
    • 0038757730 scopus 로고    scopus 로고
    • Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function
    • Qanbar R, Bouvier M: Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function. Pharmacol Ther 1, 97:1-33. 10.1016/S0163-7258(02)00300-5
    • (2003) Pharmacol Ther , vol.97 , pp. 1-33
    • Qanbar, R.1    Bouvier, M.2
  • 24
    • 33644813850 scopus 로고    scopus 로고
    • Regulation of Wnt signaling by protein-protein interaction and post-translational modifications
    • Kikuchi A, Kishida S, Yamamoto H: Regulation of Wnt signaling by protein-protein interaction and post-translational modifications. Exp Mol Med 1, 38:1-10. 10.1038/emm.2006.1
    • (2006) Exp Mol Med , vol.38 , pp. 1-10
    • Kikuchi, A.1    Kishida, S.2    Yamamoto, H.3
  • 25
    • 5444269904 scopus 로고    scopus 로고
    • Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition
    • Zhou BP, Deng J, Xia W, Xu J, Li YM, Gunduz M, Hung MC: Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol 1, 6:931-940. 10.1038/ncb1173
    • (2004) Nat Cell Biol , vol.6 , pp. 931-940
    • Zhou, B.P.1    Deng, J.2    Xia, W.3    Xu, J.4    Li, Y.M.5    Gunduz, M.6    Hung, M.C.7
  • 26
    • 33746847070 scopus 로고    scopus 로고
    • A high-throughput migration assay reveals HER2-mediated cell migration arising from increased directional persistence
    • Kumar N, Zaman MH, Kim HD, Lauffenburger DA: A high-throughput migration assay reveals HER2-mediated cell migration arising from increased directional persistence. Biophys J 1, 91:L32-L34. 10.1529/biophysj.106.088898
    • (2006) Biophys J , vol.91 , pp. L32-L34
    • Kumar, N.1    Zaman, M.H.2    Kim, H.D.3    Lauffenburger, D.A.4
  • 27
    • 84887238187 scopus 로고    scopus 로고
    • Repression of G protein-coupled receptor family C group 5 member A is associated with pathologic differentiation grade of oral squamous cell carcinoma
    • Liu SL, Zhong SS, Ye DX, Chen WT, Zhang ZY, Deng J: Repression of G protein-coupled receptor family C group 5 member A is associated with pathologic differentiation grade of oral squamous cell carcinoma. J Oral Pathol Med 1, 42:761-768. 10.1111/jop.12077
    • (2013) J Oral Pathol Med , vol.42 , pp. 761-768
    • Liu, S.L.1    Zhong, S.S.2    Ye, D.X.3    Chen, W.T.4    Zhang, Z.Y.5    Deng, J.6
  • 28
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
    • Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM, Zhou BP: Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell 1, 15:416-428. 10.1016/j.ccr.2009.03.016
    • (2009) Cancer Cell , vol.15 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3    Qiu, S.4    Evers, B.M.5    Zhou, B.P.6
  • 29
    • 0034745353 scopus 로고    scopus 로고
    • Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
    • Zhou BP, Liao Y, Xia W, Spohn B, Lee MH, Hung MC: Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nat Cell Biol 1, 3:245-252. 10.1038/35060032
    • (2001) Nat Cell Biol , vol.3 , pp. 245-252
    • Zhou, B.P.1    Liao, Y.2    Xia, W.3    Spohn, B.4    Lee, M.H.5    Hung, M.C.6


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