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Volumn 51, Issue 53, 2015, Pages 10624-10627

Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody-drug conjugate (ADC)

(10) Nunes, João P M a Morais, Maurício a Vassileva, Vessela b Robinson, Eifion a Rajkumar, Vineeth S b Smith, Mark E B a Pedley, R Barbara b Caddick, Stephen a Baker, James R a Chudasama, Vijay a

a UNIVERSITY COLLEGE LONDON (United Kingdom)

b UNIVERSITY COLLEGE LONDON (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY CONJUGATE; ANTIBODY DRUG CONJUGATE; DISULFIDE; MALEIMIDE DERIVATIVE; UNCLASSIFIED DRUG; VEDOTIN; FLUORESCENT DYE; MONOCLONAL ANTIBODY; OLIGOPEPTIDE; TRASTUZUMAB;

ARTICLE; CANCER CELL; DISULFIDE BOND; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG POTENCY; DRUG STABILITY; DRUG TARGETING; IN VITRO STUDY; IN VIVO STUDY; MCF 7 CELL LINE; CELL PROLIFERATION; CHEMISTRY; CLICK CHEMISTRY; DRUG EFFECTS; HUMAN;

ANTIBODIES, MONOCLONAL; CELL PROLIFERATION; CLICK CHEMISTRY; DISULFIDES; FLUORESCENT DYES; HUMANS; IMMUNOCONJUGATES; MCF-7 CELLS; OLIGOPEPTIDES; TRASTUZUMAB;

EID: 84934976018 PISSN: 13597345 EISSN: 1364548X Source Type: Journal
DOI: 10.1039/c5cc03557k Document Type: Article

Times cited : (101)

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