Identification of phlorizin binding domains in sodium-glucose cotransporter family: SGLT1 as a unique model system

Biochimie

Volumn 115, Issue , 2015, Pages 187-193

  Raja, Mobeen ^a,b   Kinne, Rolf K H ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

C terminal loop 13; Modeling; Phlorizin binding domain; SGLT inhibition; SGLT2 inhibitors; Sodium glucose cotransporter SGLT1

Indexed keywords

FRUCTOSE; GLUCOSIDE; MANNOSE; PHLORETIN; PHLORIZIN; SODIUM GLUCOSE COTRANSPORTER; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 2; SODIUM GLUCOSE COTRANSPORTER 3; SODIUM GLUCOSE COTRANSPORTER 4; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; PROTEIN BINDING;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; GENETIC CONSERVATION; HYPOTHESIS; MOLECULAR MODEL; PREDICTION; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; SEQUENCE ANALYSIS; ANTAGONISTS AND INHIBITORS; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; VIBRIO PARAHAEMOLYTICUS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; PHLORHIZIN; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SODIUM-GLUCOSE TRANSPORTER 1; VIBRIO PARAHAEMOLYTICUS;

EID: 84934944745     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2015.06.003     Document Type: Article

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