Cadmium toxicity induces ER stress and apoptosis via impairing energy homoeostasis in cardiomyocytes

Bioscience Reports

Volumn 35, Issue 3, 2015, Pages 1-8

  Chen, Chun Yan ^a   Zhang, Shao Li ^b   Liu, Zhi Yong ^c   Tian, Yong ^a   Sun, Qian ^a  

^a People's Hospital of Zhengzhou   (China)

^b XINXIANG MEDICAL UNIVERSITY   (China)

^c People's Hospital of Dezhou   (China)

Author keywords

AKT mammalian target of rapamycin (mTOR); Cadmium toxicity; Cardiomyocytes; Endoplasmic reticulum (ER) stress; Energy metabolism

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; ADENOSINE TRIPHOSPHATE; CADMIUM; CASPASE 3; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PROTEIN KINASE B; S6 KINASE; GLUCOSE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CADMIUM POISONING; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE TECHNIQUE; CYTOTOXICITY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENERGY HOMEOSTASIS; ENERGY METABOLISM; ENERGY YIELD; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GLUCOSE METABOLISM; HEART MUSCLE CELL; HOMEOSTASIS; INTRACELLULAR SIGNALING; MITOCHONDRIAL RESPIRATION; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN EXPRESSION; RAT; UNFOLDED PROTEIN RESPONSE; ANIMAL; CARDIAC MUSCLE CELL; CELL CULTURE; DRUG EFFECTS; GENETICS; METABOLISM; MITOCHONDRION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

MAMMALIA;

ANIMALS; APOPTOSIS; CADMIUM; CELLS, CULTURED; ENDOPLASMIC RETICULUM STRESS; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GLUCOSE; HOMEOSTASIS; MITOCHONDRIA; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-AKT; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84934942691     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20140170     Document Type: Article

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