The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Boyle, Sarah T ^a   Faulkner, Jessica W ^a   McColl, Shaun R ^a   Kochetkova, Marina ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Breast Cancer; CCR6; Chemokine Receptor; Immune System; Macrophages; Mammary Gland; Transgenic Mouse Model

Indexed keywords

BETA1 INTEGRIN; CD206 ANTIGEN; CD24 ANTIGEN; CD45 ANTIGEN; CHEMOKINE RECEPTOR CCR6; INTERLEUKIN 4 RECEPTOR; KI 67 ANTIGEN; LYMPHOCYTE ANTIGEN; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; UNCLASSIFIED DRUG; CCR6 PROTEIN, MOUSE; VIRUS T ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL; CANCER EPITHELIAL CELL; CANCER GROWTH; CANCER INCIDENCE; CANCER MODEL; CANCER STEM CELL; CELL MIGRATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENDRITIC CELL; DISEASE ASSOCIATION; GENE DELETION; GENOTYPE; HISTOPATHOLOGY; IN VIVO STUDY; KNOCKOUT MOUSE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; ONCOLOGICAL PARAMETERS; ONSET AGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSGENIC MOUSE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR INITIATION; TUMOR MICROENVIRONMENT; ANIMAL; C57BL MOUSE; CARCINOGENESIS; DISEASE MODEL; EPITHELIUM CELL; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; MACROPHAGE; METABOLISM; MOUSE MAMMARY TUMOR VIRUS; PATHOLOGY;

MOUSE MAMMARY TUMOR VIRUS; MUS; MUS MUSCULUS;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CARCINOGENESIS; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FEMALE; GENE DELETION; MACROPHAGES; MAMMARY NEOPLASMS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; MAMMARY TUMOR VIRUS, MOUSE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOPLASTIC STEM CELLS; RECEPTORS, CCR6; TUMOR MICROENVIRONMENT;

EID: 84934911199     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0394-1     Document Type: Article

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