Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism

Oncogene

Volumn 34, Issue 25, 2015, Pages 3296-3304

  Teh, J T ^a   Zhu, W L ^a,b   Ilkayeva, O R ^c   Li, Y ^a   Gooding, J ^c   Casey, P J ^a   Summers, S A ^a   Newgard, C B ^c   Wang, M ^a,b  

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; PROTEIN S ISOPRENYLCYSTEINE O METHYLTRANSFERASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; CYSMETHYNIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INDOLE DERIVATIVE; MULTIENZYME COMPLEX; PROTEIN METHYLTRANSFERASE; PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGY; BIOSYNTHESIS; CANCER CELL; CANCER GROWTH; CELL GROWTH; CELL METABOLISM; CELL PROLIFERATION; CITRIC ACID CYCLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; IN VITRO STUDY; METABOLIC REGULATION; MITOCHONDRIAL RESPIRATION; MOUSE; MULTIPLE CANCER; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIMETRY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; CARCINOGENESIS; CELL RESPIRATION; CELL SURVIVAL; DRUG EFFECTS; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYMOLOGY; HUMAN; METABOLISM; MITOCHONDRION; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; CARCINOGENESIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL RESPIRATION; CELL SURVIVAL; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; INDOLES; MITOCHONDRIA; PROTEIN METHYLTRANSFERASES;

EID: 84934905677     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.260     Document Type: Article

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