-
1
-
-
78449290844
-
The sigma-1 receptor chaperone as an inter-organelle signaling modulator
-
S0165-6147(10)00153-7/j.tips.2010.08.007
-
Su, T. P., Hayashi, T., Maurice, T., Buch, S. & Ruoho, A. E. The sigma-1 receptor chaperone as an inter-organelle signaling modulator. Trends Pharmacol Sci. 31, 557-566; doi:S0165-6147(10)00153-7/j.tips.2010.08.007 (2010).
-
(2010)
Trends Pharmacol Sci.
, vol.31
, pp. 557-566
-
-
Su, T.P.1
Hayashi, T.2
Maurice, T.3
Buch, S.4
Ruoho, A.E.5
-
2
-
-
35549006797
-
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival
-
S0092-8674(07)01099-9/j.cell.2007.08.036
-
Hayashi, T. & Su, T. P. Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival. Cell 131, 596-610; doi:S0092-8674(07)01099-9/j.cell.2007.08.036 (2007).
-
(2007)
Cell
, vol.131
, pp. 596-610
-
-
Hayashi, T.1
Su, T.P.2
-
3
-
-
84906227102
-
NMDA receptors are upregulated and trafficked to the plasma membrane after sigma-1 receptor activation in the rat hippocampus
-
Pabba, M. et al. NMDA receptors are upregulated and trafficked to the plasma membrane after sigma-1 receptor activation in the rat hippocampus. J Neurosci. 34, 11325-11338; doi:10.1523/JNEUROSCI.0458-14.2014 (2014).
-
(2014)
J Neurosci.
, vol.34
, pp. 11325-11338
-
-
Pabba, M.1
-
4
-
-
79960099287
-
Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site
-
Xu, J. et al. Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site. Nat. Commun. 2, 380; doi:10.1038/ncomms1386 (2011).
-
(2011)
Nat. Commun.
, vol.2
, pp. 380
-
-
Xu, J.1
-
5
-
-
78249273602
-
Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration-motor neuron disease
-
Luty, A. A. et al. Sigma nonopioid intracellular receptor 1 mutations cause frontotemporal lobar degeneration-motor neuron disease. Ann. Neurol. 68, 639-649; doi:10.1002/ana.22274 (2010).
-
(2010)
Ann. Neurol.
, vol.68
, pp. 639-649
-
-
Luty, A.A.1
-
6
-
-
84155163741
-
A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis
-
Al-Saif, A., Al-Mohanna, F. & Bohlega, S. A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis. Ann. Neurol. 70, 913-919; doi:10.1002/ana.22534 (2011).
-
(2011)
Ann. Neurol.
, vol.70
, pp. 913-919
-
-
Al-Saif, A.1
Al-Mohanna, F.2
Bohlega, S.3
-
7
-
-
84875768176
-
Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis
-
Prause, J. et al. Altered localization, abnormal modification and loss of function of Sigma receptor-1 in amyotrophic lateral sclerosis. Human molecular genetics 22, 1581-1600; doi:10.1093/hmg/ddt008 (2013).
-
(2013)
Human Molecular Genetics
, vol.22
, pp. 1581-1600
-
-
Prause, J.1
-
8
-
-
84861191824
-
Association between a variant of the sigma-1 receptor gene and Alzheimer's disease
-
Feher, A. et al. Association between a variant of the sigma-1 receptor gene and Alzheimer's disease. Neurosci. Lett. 517, 136-139; doi:10.1016/j.neulet.2012.04.046 (2012).
-
(2012)
Neurosci. Lett.
, vol.517
, pp. 136-139
-
-
Feher, A.1
-
9
-
-
80054088423
-
Genetic polymorphisms in sigma-1 receptor and apolipoprotein e interact to influence the severity of Alzheimer's disease
-
Huang, Y. et al. Genetic polymorphisms in sigma-1 receptor and apolipoprotein E interact to influence the severity of Alzheimer's disease. Curr. Alzheimer Res. 8, 765-770 (2011).
-
(2011)
Curr. Alzheimer Res.
, vol.8
, pp. 765-770
-
-
Huang, Y.1
-
10
-
-
42049089609
-
Low density of sigma1 receptors in early Alzheimer's disease
-
Mishina, M. et al. Low density of sigma1 receptors in early Alzheimer's disease. Ann. Nucl. Med. 22, 151-156; doi:10.1007/s12149-007-0094-z (2008).
-
(2008)
Ann. Nucl. Med.
, vol.22
, pp. 151-156
-
-
Mishina, M.1
-
11
-
-
22344445245
-
Function of sigma1 receptors in Parkinson's disease
-
Mishina, M. et al. Function of sigma1 receptors in Parkinson's disease. Acta Neurol. Scand. 112, 103-107; doi:10.1111/j.1600-0404.2005.00432.x (2005).
-
(2005)
Acta Neurol. Scand.
, vol.112
, pp. 103-107
-
-
Mishina, M.1
-
12
-
-
62849105979
-
Association between sigma-1 receptor gene polymorphism and prefrontal hemodynamic response induced by cognitive activation in schizophrenia
-
Takizawa, R. et al. Association between sigma-1 receptor gene polymorphism and prefrontal hemodynamic response induced by cognitive activation in schizophrenia. Prog. Neuropsychopharmacol Biol. Psychiatry 33, 491-498; doi:10.1016/j.pnpbp.2009.01.014 (2009).
-
(2009)
Prog. Neuropsychopharmacol Biol. Psychiatry
, vol.33
, pp. 491-498
-
-
Takizawa, R.1
-
13
-
-
84875783898
-
Lack of sigma-1 receptor exacerbates ALS progression in mice
-
Mavlyutov, T. A. et al. Lack of sigma-1 receptor exacerbates ALS progression in mice. Neuroscience 240, 129-134; doi:10.1016/j. neuroscience.2013.02.035 (2013).
-
(2013)
Neuroscience
, vol.240
, pp. 129-134
-
-
Mavlyutov, T.A.1
-
14
-
-
84886816838
-
Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation
-
Peviani, M. et al. Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation. Neurobiol. Dis. 62, 218-232; doi:10.1016/j.nbd.2013.10.010 (2014).
-
(2014)
Neurobiol. Dis.
, vol.62
, pp. 218-232
-
-
Peviani, M.1
-
15
-
-
84877337663
-
Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models
-
Hedskog, L. et al. Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models. Proc. Natl. Acad. Sci. USA 110, 7916-7921; doi:10.1073/pnas.1300677110 (2013).
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 7916-7921
-
-
Hedskog, L.1
-
16
-
-
84903529679
-
Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism
-
Francardo, V. et al. Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism. Brain 137, 1998-2014; doi:10.1093/brain/awu107 (2014).
-
(2014)
Brain
, vol.137
, pp. 1998-2014
-
-
Francardo, V.1
-
17
-
-
84879392732
-
Sigma-1 receptor agonist PRE084 is protective against mutant huntingtin-induced cell degeneration: Involvement of calpastatin and the NF-kappaB pathway
-
Hyrskyluoto, A. et al. Sigma-1 receptor agonist PRE084 is protective against mutant huntingtin-induced cell degeneration: involvement of calpastatin and the NF-kappaB pathway. Cell Death Dis. 4, e646; doi:10.1038/cddis.2013.170 (2013).
-
(2013)
Cell Death Dis.
, vol.4
, pp. e646
-
-
Hyrskyluoto, A.1
-
18
-
-
84857134134
-
Sigma-1 receptor agonists as therapeutic drugs for cognitive impairment in neuropsychiatric diseases
-
Niitsu, T., Iyo, M. & Hashimoto, K. Sigma-1 receptor agonists as therapeutic drugs for cognitive impairment in neuropsychiatric diseases. Curr. Pharm. Des. 18, 875-883 (2012).
-
(2012)
Curr. Pharm. Des.
, vol.18
, pp. 875-883
-
-
Niitsu, T.1
Iyo, M.2
Hashimoto, K.3
-
19
-
-
84872567654
-
Dynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine
-
Kourrich, S. et al. Dynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine. Cell 152, 236-247; doi:10.1016/j.cell.2012.12.004 (2013).
-
(2013)
Cell
, vol.152
, pp. 236-247
-
-
Kourrich, S.1
-
20
-
-
60149107790
-
The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator
-
323/5916/934
-
Fontanilla, D. et al. The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator. Science 323, 934-937; doi:323/5916/934 (2009).
-
(2009)
Science
, vol.323
, pp. 934-937
-
-
Fontanilla, D.1
-
21
-
-
84894046027
-
Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensorynerve mitochondrial abnormalities and neuropathic pain in mice
-
Nieto, F. R. et al. Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensorynerve mitochondrial abnormalities and neuropathic pain in mice. Mol. Pain 10, 11; doi:10.1186/1744-8069-10-11 (2014).
-
(2014)
Mol. Pain
, vol.10
, pp. 11
-
-
Nieto, F.R.1
-
22
-
-
84869878432
-
The sigma-1 receptor: Roles in neuronal plasticity and disease
-
Kourrich, S., Su, T. P., Fujimoto, M. & Bonci, A. The sigma-1 receptor: roles in neuronal plasticity and disease. Trends Neurosci. 35, 762-771; doi:10.1016/j.tins.2012.09.007 (2012).
-
(2012)
Trends Neurosci.
, vol.35
, pp. 762-771
-
-
Kourrich, S.1
Su, T.P.2
Fujimoto, M.3
Bonci, A.4
-
23
-
-
77950858460
-
The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study
-
S0306-4522(10)00218-6
-
Mavlyutov, T. A., Epstein, M. L., Andersen, K. A., Ziskind-Conhaim, L. & Ruoho, A. E. The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study. Neuroscience 167, 247-255; doi:S0306-4522(10)00218-6 (2010).
-
(2010)
Neuroscience
, vol.167
, pp. 247-255
-
-
Mavlyutov, T.A.1
Epstein, M.L.2
Andersen, K.A.3
Ziskind-Conhaim, L.4
Ruoho, A.E.5
-
24
-
-
4444238110
-
Effects of neurosteroids on ischemia-reperfusion injury in the rat retina: Role of sigma1 recognition sites
-
Bucolo, C. & Drago, F. Effects of neurosteroids on ischemia-reperfusion injury in the rat retina: role of sigma1 recognition sites. Eur J. Pharmacol. 498, 111-114; doi:10.1016/j.ejphar.2004.06.067 (2004).
-
(2004)
Eur J. Pharmacol.
, vol.498
, pp. 111-114
-
-
Bucolo, C.1
Drago, F.2
-
25
-
-
53149105545
-
In vivo protection against retinal neurodegeneration by sigma receptor 1 ligand (+)-pentazocine
-
Smith, S. B. et al. In vivo protection against retinal neurodegeneration by sigma receptor 1 ligand (+)-pentazocine. Invest Ophthalmol Vis. Sci. 49, 4154-4161; doi:10.1167/iovs.08-1824 (2008).
-
(2008)
Invest Ophthalmol Vis. Sci.
, vol.49
, pp. 4154-4161
-
-
Smith, S.B.1
-
26
-
-
56149083457
-
Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction
-
Tchedre, K. T. et al. Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction. Invest Ophthalmol Vis. Sci. 49, 4993-5002; doi:10.1167/iovs.08-1867 (2008).
-
(2008)
Invest Ophthalmol Vis. Sci.
, vol.49
, pp. 4993-5002
-
-
Tchedre, K.T.1
-
27
-
-
79955642334
-
Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor
-
Mavlyutov, T. A., Nickells, R. W. & Guo, L. W. Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor. Mol. Vis. 17, 1034-1043 (2011).
-
(2011)
Mol. Vis.
, vol.17
, pp. 1034-1043
-
-
Mavlyutov, T.A.1
Nickells, R.W.2
Guo, L.W.3
-
28
-
-
84862833548
-
Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (sigmaR1)
-
Ha, Y. et al. Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (sigmaR1). Invest Ophthalmol. Vis. Sci. 52, 7749-7760; doi:10.1167/iovs.11-8169 (2011).
-
(2011)
Invest Ophthalmol. Vis. Sci.
, vol.52
, pp. 7749-7760
-
-
Ha, Y.1
-
29
-
-
67349177794
-
Increased expression of catalase and superoxide dismutase 2 reduces cone cell death in retinitis pigmentosa
-
Usui, S. et al. Increased expression of catalase and superoxide dismutase 2 reduces cone cell death in retinitis pigmentosa. Mol. Ther. 17, 778-786; doi:10.1038/mt.2009.47 (2009).
-
(2009)
Mol. Ther.
, vol.17
, pp. 778-786
-
-
Usui, S.1
-
30
-
-
77952548705
-
Expression of sigma receptor 1 mRNA and protein in rat retina
-
Liu, L. L., Wang, L., Zhong, Y. M. & Yang, X. L. Expression of sigma receptor 1 mRNA and protein in rat retina. Neuroscience 167, 1151-1159, doi:10.1016/j.neuroscience.2010.03.006 (2010).
-
(2010)
Neuroscience
, vol.167
, pp. 1151-1159
-
-
Liu, L.L.1
Wang, L.2
Zhong, Y.M.3
Yang, X.L.4
-
31
-
-
33751399402
-
Purification and characterization of the guinea pig sigma-1 receptor functionally expressed in Escherichia coli
-
Ramachandran, S., Lu, H., Prabhu, U. & Ruoho, A. E. Purification and characterization of the guinea pig sigma-1 receptor functionally expressed in Escherichia coli. Protein Expr. Purif 51, 283-292 (2007).
-
(2007)
Protein Expr. Purif
, vol.51
, pp. 283-292
-
-
Ramachandran, S.1
Lu, H.2
Prabhu, U.3
Ruoho, A.E.4
-
32
-
-
0035500397
-
Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina
-
Ola, M. S. et al. Expression pattern of sigma receptor 1 mRNA and protein in mammalian retina. Brain Res. Mol. Brain Res. 95, 86-95 (2001).
-
(2001)
Brain Res. Mol. Brain Res.
, vol.95
, pp. 86-95
-
-
Ola, M.S.1
-
33
-
-
35648956677
-
Ligand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 cells
-
1750-2187-2-8
-
Mavlyutov, T. A. & Ruoho, A. E. Ligand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 cells. J. Mol. Signal. 2, 8, doi:1750-2187-2-8 (2007).
-
(2007)
J. Mol. Signal.
, vol.2
, pp. 8
-
-
Mavlyutov, T.A.1
Ruoho, A.E.2
-
34
-
-
27644548928
-
Beyond counting photons: Trials and trends in vertebrate visual transduction
-
Burns, M. E. & Arshavsky, V. Y. Beyond counting photons: trials and trends in vertebrate visual transduction. Neuron 48, 387-401; doi:10.1016/j.neuron.2005.10.014 (2005).
-
(2005)
Neuron
, vol.48
, pp. 387-401
-
-
Burns, M.E.1
Arshavsky, V.Y.2
-
35
-
-
84893605356
-
Presynaptic [Ca(2+)] and GCAPs: Aspects on the structure and function of photoreceptor ribbon synapses
-
Schmitz, F. Presynaptic [Ca(2+)] and GCAPs: aspects on the structure and function of photoreceptor ribbon synapses. Front Mol. Neurosci. 7, 3; doi:10.3389/fnmol.2014.00003 (2014).
-
(2014)
Front Mol. Neurosci.
, vol.7
, pp. 3
-
-
Schmitz, F.1
-
36
-
-
84871001231
-
Sigma-1 receptor stimulation attenuates calcium influx through activated L-type voltage gated calcium channels in purified retinal ganglion cells
-
Mueller, B. H., 2nd et al. Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells. Exp Eye Res 107, 21-31; doi:10.1016/j.exer.2012.11.002 (2013).
-
(2013)
Exp Eye Res
, vol.107
, pp. 21-31
-
-
Mueller, B.H.1
-
37
-
-
47249147955
-
Sigma-1 receptors protect RGC-5 cells from apoptosis by regulating intracellular calcium, Bax levels, and caspase-3 activation
-
Tchedre, K. T. & Yorio, T. sigma-1 receptors protect RGC-5 cells from apoptosis by regulating intracellular calcium, Bax levels, and caspase-3 activation. Invest Ophthalmol Vis. Sci. 49, 2577-2588; doi:10.1167/iovs.07-1101 (2008).
-
(2008)
Invest Ophthalmol Vis. Sci.
, vol.49
, pp. 2577-2588
-
-
Tchedre, K.T.1
Yorio, T.2
-
38
-
-
79952004386
-
Activation of the zeta receptor 1 suppresses NMDA responses in rat retinal ganglion cells
-
Zhang, X. J., Liu, L. L., Jiang, S. X., Zhong, Y. M. & Yang, X. L. Activation of the zeta receptor 1 suppresses NMDA responses in rat retinal ganglion cells. Neuroscience 177, 12-22; doi:10.1016/j.neuroscience.2010.12.064 (2011).
-
(2011)
Neuroscience
, vol.177
, pp. 12-22
-
-
Zhang, X.J.1
Liu, L.L.2
Jiang, S.X.3
Zhong, Y.M.4
Yang, X.L.5
-
39
-
-
34248198347
-
Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells
-
Jiang, G. et al. Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells. Invest Ophthalmol Vis. Sci. 47, 5576-5582; doi:10.1167/iovs.06-0608 (2006).
-
(2006)
Invest Ophthalmol Vis. Sci.
, vol.47
, pp. 5576-5582
-
-
Jiang, G.1
-
40
-
-
0033565860
-
Colocalization of sterol isomerase and sigma(1) receptor at endoplasmic reticulum and nuclear envelope level
-
Dussossoy, D. et al. Colocalization of sterol isomerase and sigma(1) receptor at endoplasmic reticulum and nuclear envelope level. Eur. J. Biochem. 263, 377-386 (1999).
-
(1999)
Eur. J. Biochem.
, vol.263
, pp. 377-386
-
-
Dussossoy, D.1
-
41
-
-
84898057760
-
Accumulation of the sigma-1 receptor is common to neuronal nuclear inclusions in various neurodegenerative diseases
-
Miki, Y. et al. Accumulation of the sigma-1 receptor is common to neuronal nuclear inclusions in various neurodegenerative diseases. Neuropathology 34, 148-158; doi:10.1111/neup.12080 (2014).
-
(2014)
Neuropathology
, vol.34
, pp. 148-158
-
-
Miki, Y.1
-
42
-
-
0036707864
-
Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization
-
tra030905
-
Mavlyutov, T. A., Cai, Y. & Ferreira, P. A. Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization. Traffic 3, 630-640; doi:tra030905 (2002).
-
(2002)
Traffic
, vol.3
, pp. 630-640
-
-
Mavlyutov, T.A.1
Cai, Y.2
Ferreira, P.A.3
|