A novel mGlu4 selective agonist LSP4-2022 increases behavioral despair in mouse models of antidepressant action

Neuropharmacology

Volumn 97, Issue , 2015, Pages 338-345

  Podkowa, Karolina ^a   Rzeźniczek, Szymon ^a   Marciniak, Marcin ^a   Acher, Francine ^b   Pilc, Andrzej ^a,c   Pałucha Poniewiera, Agnieszka ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

^b CNRS   (France)

^c JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Depression; LSP4 2022; mGlu4 receptor; mGlu7 receptor

Indexed keywords

ANTIDEPRESSANT AGENT; IMIPRAMINE; LSP 4 2022; METABOTROPIC RECEPTOR 4; METABOTROPIC RECEPTOR 4 AGONIST; METABOTROPIC RECEPTOR AGONIST; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR STIMULATING AGENT; LSP4-2022; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 7; PHOSPHINIC ACID DERIVATIVE; PSYCHOTROPIC AGENT; TRICYCLIC ANTIDEPRESSANT AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG SELECTIVITY; FORCED SWIM TEST; HOPELESSNESS; KNOCKOUT MOUSE; LOCOMOTION; MALE; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; TAIL SUSPENSION TEST; AGONISTS; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; FRONTAL LOBE; GENETICS; HIPPOCAMPUS; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID AGONISTS; FRONTAL LOBE; HIPPOCAMPUS; IMIPRAMINE; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; PHOSPHINIC ACIDS; PSYCHOTROPIC DRUGS; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 84934782900     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2015.05.039     Document Type: Article

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